Serum total and high density lipoprotein (HDL) cholesterol concentrations in rural and urban boys from 16 countries

Knuiman, J.T.; Hermus, R.J.J.; Hautvast, J.G.A.J.

doi:10.1016/0021-9150(80)90245-2

Cited by 130 publications

(44 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…35 In Nigeria, Ghana and Cote d'Ivoire, the levels in all the age groups range from 116 to 166 mg/dl. 36,37 A slightly higher level was found in Zimbabwe among 238 urban black men in an occupationally stratified sample, with higher levels being observed in the upper socioeconomic groups. 38 Trends in CAD in sub-Saharan Africans O Akinboboye et al in women.…”

Section: Trends In Cad Inmentioning

confidence: 83%

Trends in coronary artery disease and associated risk factors in sub-Saharan Africans

Akinboboye

Idris²,

Akinkugbe

2003

J Hum Hypertens

View full text Add to dashboard Cite

It has been suggested that the prevalence of coronary artery disease (CAD) is steadily increasing in subSaharan Africa. To address this issue, we conducted a Medline search of English language articles on cardiovascular diseasesFand specifically CAD in AfricaF from 1966 to 1997. The prevalence of CAD and related complications is relatively low in most regions in Africa compared to that obtained in the economically developed countries, although the situation is rapidly changing due to trends in urbanization, changes in lifestyle, acquisition of technology and the increasing numbers of tertiary care institutions. There are variations in reported prevalence rates within the different regions, but there is an upward trend in all the regions of the sub-Saharan Africa. This trend is believed to be related to the increasing frequencies of CAD risk factors in the subcontinent.

show abstract

Section: Trends In Cad Inmentioning

confidence: 83%

Trends in coronary artery disease and associated risk factors in sub-Saharan Africans

Akinboboye

Idris²,

Akinkugbe

2003

J Hum Hypertens

View full text Add to dashboard Cite

show abstract

“…Recent studies show that cholesterol levels of children in a given geographic region would be directly related to the prevalence of coronary artery disease during adulthood in the same region. 12,[16][17][18] Because of this, since Page 12 2006, the Brazilian Society of Cardiology (SBC) started recommending cut-off for total cholesterol in children and adolescents in 150 mg/dl and routine supervision from 170 mg cholesterol/dl of blood for prevention cardiovascular diseases. 13 Studies also show that HDL-C have a protective role in the development of atherogenesis 19,20 ; and the increase of its levels would be directly associated with reduced cardiovascular risk.…”

Section: Discussionmentioning

confidence: 99%

A Decade of Lipid Profiles: A Gender Focus

Leão¹,

Carvalho²,

Galvão³

et al. 2016

Heart Res Open J

View full text Add to dashboard Cite

Introduction and Objectives:The lipid profile is an important predictor of the risk of coronary heart disease (CHD). Higher rates of total cholesterol (TC) and cholesterol of low-density lipoprotein (LDL-C) increase the chances of developing this disease. However, it is known that women due to hormonal factors would have fewer cardiovascular events. The main objective of this article is to assess the association among different parameters of the lipid profile between the different sexes in the population of a city in Brazil. Methods: This is a descriptive, longitudinal and retrospective study based on secondary data collected in the period from 2003 to 2013 in a medical laboratory in Aracaju, Brazil. The lipid profile was determined using the following markers: total cholesterol (TC); high-density lipoprotein cholesterol (HDL-C); low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG). Statistical analysis was performed using measures of central tendency and variance. The inferential analysis was performed by student's t test and the p-value was 0.05. Results: The sample consists of 63,396 people, 24,425 male and 38,971 female, with mean age of 42.02±17.38 years. The mean value of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride was respectively, 193.39±43.62 mg/dl, 48.80±11.24 mg/dl, 118.35±36.75 mg/dl and 131.28±82.21 mg/dl. Between the genres, it was observed statistical significant differences between all parameters of lipid profile (p<0.0001). Conclusion: We concluded that women have higher rates of total cholesterol and low-density lipoprotein cholesterol; while men have lower rates of high-density lipoprotein cholesterol and higher of triglyceride, which predisposes males to the development of metabolic syndrome.

show abstract

“…The definition of hypercholesterolemia in children may vary among different populations 30 and cannot 27 Since concern has been expressed about the effectiveness and safety of lipid-lowering treatments in children 12 and since the benefit derived from reduction of moderately raised serum cholesterol levels has not been clearly established even in adulthood, the highest value, that is, 6.4 mmol/L, was chosen as a cutoff point for the control group of children.…”

Section: Discussionmentioning

confidence: 99%

Increased intima-media thickness of the common carotid artery in hypercholesterolemic children.

Pauciullo

Iannuzzi

Sartorio

et al. 1994

Arterioscler Thromb

133

View full text Add to dashboard Cite

Common carotid intima-media thickness was measured by B-mode ultrasound imaging in 46 children (mean age, 7.4 years) with serum cholesterol 26.4 mmol/L (mean, 8.25 mmol/L) and in 48 children (mean age, 6.4 years) with serum cholesterol <6.4 mmol/L (mean, 4.60 mmol/L). Maximum thickness was significantly higher in hypercholesterolemic children than in control children (0.50 versus 0.47 mm, P=.007). Subgroup analysis showed that only in children >6.2 years old (the median of all the children's ages) was maximum thickness significantly higher in hypercholesterolemic children than in control children (0.51 versus 0.48 mm, P=.O14). The odds ratio (OR) of common carotid intima-media thickening T he relationship between hypercholesterolemia and coronary artery diseases (CAD) has been proved in adult CAD patients. 1 " 3 The significance of this relationship is more controversial in healthy subjects, particularly if their serum cholesterol is <6.4 mmol/L, 4 -6 Children form a special subgroup of healthy individuals.Population-based or "high-risk"-based screenings for serum cholesterol are usually recommended, 710 although others oppose this view on the basis of potential harm and of nonproven efficacy in the prevention of adult CAD. 1112Autopsy studies on arterial specimens of human subjects have shown that fatty streaks (nonraised lesions) can be found in the aortas even of 3-year-olds 13 and appear in the coronary arteries during the second decade of life.14 More advanced coronary atherosclerosis was seen in a majority of young adults in whom autopsies were performed during the Korean and Vietnam wars. -16 Aortic fatty streaks detected in subjects who had died between full-term birth and age 29 years appeared to be strongly related to antemortem levels of both total and low-density lipoprotein (LDL) cholesterol. 17 Raised lesions, like fibrous plaques, are related to clinical CAD, 18 but the progression of fatty streaks to fibrous plaques is uncertain. Arterial fibrous plaques have been found in autopsy specimens from children, Received October 5, 1993; revision accepted March 25, 1994. From the Institute of Internal Medicine and Metabolic Diseases and the Department of Pediatrics (R.S., A. Di C), Federico II University, Naples, Italy.Correspondence to Dr Paolo Pauciullo, Institute of Internal Medicine and Metabolic Diseases, Federico II University, Via Sergio Pansini, 5, 80131 Naples, Italy.© 1994 American Heart Association, Inc.(maximum thickness of the far wall higher than the 95th percentile of the control group, 0.51 mm) between patients and control subjects was statistically significant both in univariate analysis (OR, 6.39; 95% confidence interval, 1.19 to 32.3; f>=.025) and after age (OR, 5.96; 95% confidence interval, 1.09 to 32.4; P=.O39) and sex (OR, 7.54; 95% confidence interval, 1.38 to 41.2; P=.02O) were controlled for. Children >6 years old with serum cholesterol ^6.4 mmol/L show increased thickness of the common carotid intima-media.

show abstract

Serum total and high density lipoprotein (HDL) cholesterol concentrations in rural and urban boys from 16 countries

Cited by 130 publications

References 20 publications

Trends in coronary artery disease and associated risk factors in sub-Saharan Africans

Trends in coronary artery disease and associated risk factors in sub-Saharan Africans

A Decade of Lipid Profiles: A Gender Focus

Increased intima-media thickness of the common carotid artery in hypercholesterolemic children.

Contact Info

Product

Resources

About