A Decade of Lipid Profiles: A Gender Focus

Abstract

Introduction and Objectives:The lipid profile is an important predictor of the risk of coronary heart disease (CHD). Higher rates of total cholesterol (TC) and cholesterol of low-density lipoprotein (LDL-C) increase the chances of developing this disease. However, it is known that women due to hormonal factors would have fewer cardiovascular events. The main objective of this article is to assess the association among different parameters of the lipid profile between the different sexes in the population of a city in Brazil. Methods: This is a descriptive, longitudinal and retrospective study based on secondary data collected in the period from 2003 to 2013 in a medical laboratory in Aracaju, Brazil. The lipid profile was determined using the following markers: total cholesterol (TC); high-density lipoprotein cholesterol (HDL-C); low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG). Statistical analysis was performed using measures of central tendency and variance. The inferential analysis was performed by student's t test and the p-value was 0.05. Results: The sample consists of 63,396 people, 24,425 male and 38,971 female, with mean age of 42.02±17.38 years. The mean value of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride was respectively, 193.39±43.62 mg/dl, 48.80±11.24 mg/dl, 118.35±36.75 mg/dl and 131.28±82.21 mg/dl. Between the genres, it was observed statistical significant differences between all parameters of lipid profile (p<0.0001). Conclusion: We concluded that women have higher rates of total cholesterol and low-density lipoprotein cholesterol; while men have lower rates of high-density lipoprotein cholesterol and higher of triglyceride, which predisposes males to the development of metabolic syndrome.

Association between Hypertriglyceridemia and Disease Severity in Visceral Leishmaniasis

“…10 Another study in adults (42.02 6 17.38y) show a mean 6 SD of total cholesterol 193.39 6 43.62 mg/dL, HDL 48.80 6 11.24 mg/dL, LDL 118.35 6 36.75 mg/dL, and triglycerides 131.28 6 82.21 mg/dl. 11 These data clearly show that the lipid profile of the patients from the present study is not a trend from the normal population from the same state of Brazil, independently of the age. Importantly, the present findings confirm that these patients classified as severe present a higher frequency of disease complications such as mucosal bleeding, associated infections, lower platelet and neutrophil counts, and edema.…”

Age-Related Changes in Lipid and Glucose Levels Associated with Drug Use and Mortality: An Observational Study

“…In a population-based cross-sectional study involving only healthy and drug-free subjects, age-related trends in serum glucose and lipid profiles were analyzed [38]. Leao et al [43] conducted a longitudinal and retrospective study and investigated the association between lipid-related parameters and gender. Natali el al.…”