Serum oxidative stress, visfatin and apelin in healthy women and those with premenstrual syndrome

Incebiyik, Adnan; Camuzcuoğlu, Aysun; Hilali, Neşe Gül; Ulaş, Turgay; Vural, Mehmet; Camuzcuoğlu, Hakan; Aksoy, Nurten

doi:10.3109/01443615.2014.948399

Cited by 13 publications

(20 citation statements)

References 34 publications

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“…Increased serum adiponectin was assumed to be compensatory for early vascular endothelial damage and may have anti-inflammatory and antioxidative properties [ 6 , 17 ]. On the contrary, visfatin can serve as a marker of insulin resistance with proinflammatory and prooxidant condition [ 8 , 19 , 47 , 48 ]. This is particularly important due to the fact that smoking even in small amounts may cause endothelial dysfunction and transient uteroplacental vasoconstriction [ 6 , 49 ].…”

Section: Discussionmentioning

confidence: 99%

“…In accordance with the findings of other authors, in our study visfatin correlated positively with ox-LDL, TOC, and OSI and negatively with TAC, which can suggest its prooxidative capacity [ 55 , 56 ]. The lower level of visfatin coexisting with higher levels of TOC, OSI, and lipid hydroperoxide in women with premenstrual syndrome was observed [ 47 ]. The current study reported that in both the smoking and nonsmoking groups ox-LDL was a main predictor of adiponectin and visfatin concentrations in cord blood.…”

Section: Discussionmentioning

confidence: 99%

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Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and NonexposedIn Uteroto Tobacco Smoke

Chełchowska¹,

Ambroszkiewicz²,

Gajewska³

et al. 2016

Oxidative Medicine and Cellular Longevity

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Aims. Maternal smoking is considered as a source of oxidative stress, which has been implicated to disrupted adipokines expression in adipose tissue. We examined the relationship between selected adipokines and markers of oxidative stress/antioxidant defence in the umbilical cord of neonates exposed and nonexposed in utero to tobacco smoke. Methods. Subjects including 85 healthy neonates (born to 41 smokers and 44 nonsmokers) were tested for adiponectin, visfatin, oxidized low density lipoprotein (ox-LDL), total oxidant capacity (TOC), and total antioxidant capacity (TAC). Results. Cord serum visfatin, ox-LDL, and TOC were significantly higher (p < 0.001) but adiponectin and TAC were lower (p < 0.001 and p < 0.05, resp.) in smoking group than in tobacco abstinents. In whole group of children (adjusted for smoking status, gender, and birth weight) adiponectin showed negative and visfatin positive correlations with ox-LDL. In the model estimated separately for smokers ox-LDL explained 36% of adiponectin and 35.5% of visfatin variance, while in the model of nonsmokers it explained 36.8% and 69.4%, respectively. Conclusion. Maternal smoking enhances oxidative status and depletes antioxidant potential in newborns. Lower level of adiponectin and higher visfatin concentration seem to be related with a less beneficial oxidative stress profile and higher level of lipid peroxidation in neonates exposed and nonexposed in utero to tobacco smoke.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and NonexposedIn Uteroto Tobacco Smoke

Chełchowska¹,

Ambroszkiewicz²,

Gajewska³

et al. 2016

Oxidative Medicine and Cellular Longevity

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“…Higher antioxidant activity of 30 µl tea in comparison to lower amounts in preventing LDL-C oxidation is logical as the higher tea amount would have higher quantities of phenolic compounds and an increased antioxidant activity; this is in agreement with previously reported findings [ 43 , 46 ]. So it could be postulated that therapeutic effect of S. persicae on endometriosis [ 47 ], removing blood stasis [ 22 ], and menstrual irregularity [ 21 ] could be partly through its antioxidant properties, as an association between oxidative stress and these disorders has been previously reported [ 4 , 6 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…Oxidative stress, an imbalance between formation and elimination of reactive oxygen species (ROS), is one of the major causes of many diseases including cancer [ 1 ], diabetes mellitus [ 2 ], atherosclerosis [ 3 ], and more importantly gynecological diseases especially endometriosis [ 4 ], polycystic ovarian syndrome (PCOS) [ 5 ], and menstruation disturbances [ 6 , 7 ]. Such negative effects of excessive ROS are due to oxidative damage of various cellular components including lipids, proteins, and nucleic acids [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria

Fattahi

Raffel

et al. 2017

Eur J Med Res

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BackgroundLittle information is available concerning antioxidant effects of plant teas (water boiled) which are used more commonly in traditional Chinese medicine than other extracts. Thus, we addressed this issue by evaluating the ability of teas from four different plants with therapeutic potential on gynecological diseases.MethodsThe aqueous extracts of Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria rhizome were prepared and then their effects on copper-induced low-density lipoprotein cholesterol (LDL-C) oxidation were evaluated by spectrophotometric method. Density gradient ultracentrifugation method was recruited to isolate LDL-C from healthy individuals.ResultsOur results showed that adding 10, 20, and 30 µl S. persicae could increase the lag phase duration of LDL-C oxidation compared with control reaction 12, 21, and 33%, respectively. The most effective delay (87%) was observed when 30 µl H. diffusa was added to the reaction. In cases of L. cardiaca and C. zedoaria, we found no significant influence on the lag phase duration (p > 0.05). Moreover, our findings about starting point of the decomposition phase were almost in parallel with the lag phase results, as 30 µl of S. persicae or H. diffusa teas could significantly increase the initiation time of decomposition (p < 0.05).ConclusionsIn conclusion our results showed that both S. persicae and H. diffusa teas and not L. cardiaca and C. zedoaria could have medicinal therapeutic effects partly through direct oxidation prevention.

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“…A recent study described increased lipid hydroperoxide, which is commonly used to assess oxidative levels, and decreased TAC in subjects with PMS in their luteal phases [5]. Another group reported that subjects with PMS had total oxidant status (TOS) levels non-significantly higher that and TAC levels similar with those of controls [32]. In another study, elevated levels of nitric oxide (NO), a well-known antioxidant, were reported in PMS patients at the beginning of the menstrual cycle.…”

Section: Introductionmentioning

confidence: 97%

Total oxidant–antioxidant and paraoxonase-1 levels in premenstrual dysphoric disorder: a follow-up study

Özcan

Oral

Güleç

et al. 2017

Psychiatry and Clinical Psychopharmacology

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Objective: Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS) that was categorized as a mood disorder in the most recent version of the Diagnostic and Statistical Manual for Mental Disorders. In addition to a history of PMS, a PMDD diagnosis requires prospective symptom assessment for 2 consecutive menstrual periods. Although the effects of some oxidants-antioxidants were previously studied in PMS, their possible effects in PMDD remain unknown. Paraoxonase-1 (PON-1) is a new high-density lipoproteinassociated enzyme with many antioxidative effects. We hypothesized that assessing serum total oxidant-antioxidant and PON-1 levels could clarify the role of oxidant-antioxidant system in PMDD. Methods: All participants (n = 50) were assessed by an experienced psychiatrist for PMDD by using the Diagnostic and Statistical Manual for Mental Disorders-IV (DSM-IV), Premenstrual Assessment Form and Daily Record of Severity of Problems (DRSP)-Short Form or possible psychiatric disorders including depression, anxiety, and sleep disorders. Serum estrogen, progesterone, total oxidant-antioxidant, and paraoxonase-1 (PON-1) levels were measured in the serum of 20 participants with PMDD and 30 asymptomatic controls during the follicular and luteal phases of two consecutive menstrual cycles. Sleep quality, depression, and anxiety symptoms were assessed with the Pittsburg Sleep Quality Index (PSQI), Hamilton Depression Rating Scale (HDRS), and Hamilton Anxiety Rating Scale (HARS), respectively. Results: There were no significant intergroup differences in estrogen, progesterone, oxidantantioxidant, or PON-1 levels or PSQI scores. However, the mean HDRS and HARS scores were statistically significantly higher for patients with PMDD than for controls. Levels of estrogen, progesterone, and total oxidant-antioxidant were not correlated with HDRS, HARS, or PSQI scores. Conclusions: Considering the lack of differences in hormonal and biochemical levels between the two groups, it may be more efficient and discriminative to longitudinally assess biochemical and cellular stress-related parameters in subjects with PMDD. ARTICLE HISTORY

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Serum oxidative stress, visfatin and apelin in healthy women and those with premenstrual syndrome

Cited by 13 publications

References 34 publications

Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and NonexposedIn Uteroto Tobacco Smoke

Cord Blood Adiponectin and Visfatin Concentrations in relation to Oxidative Stress Markers in Neonates Exposed and NonexposedIn Uteroto Tobacco Smoke

Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria

Total oxidant–antioxidant and paraoxonase-1 levels in premenstrual dysphoric disorder: a follow-up study

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