2018
DOI: 10.2174/1874303x01811010100
|View full text |Cite
|
Sign up to set email alerts
|

Serum Neutrophil Gelatinase-associated Lipocalin Measured at Admission to Predict Mortality in Sepsis-associated Acute Kidney Injury of Vietnamese Critically Ill Patients

Abstract: Purpose: To evaluate incidence of sepsis-associated acute kidney injury (SA-AKI) in the AKI Intensive Care Unit (ICU) patients and predictive value of Neutrophil Gelatinase-Associated Lipocalin (NGAL) measured at the admission in mortality of SA-AKI and non SA-AKI. Patients and Methods: A study of 101 consecutive adult patients admitted to the Intensive Care Unit (ICU) diagnosed as AKI in which there were 60 patients … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0

Year Published

2019
2019
2020
2020

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 2 publications
(3 citation statements)
references
References 30 publications
0
3
0
Order By: Relevance
“…Infections, sepsis, shock, need for mechanical ventilation, and surgery are well recognized as high-risk factors for the development of AKI [ 28 ]. Sepsis has been reported to account for approximately 50% of patients with AKI in ICU, and it has been hypothesized that the modulation of proinflammatory cytokines in septic AKI might be beneficial [ 8 , 15 ]. Sepsis mediated hypoperfusion leading to tubular necrosis traditionally has been cited as the primary pathophysiology for SA-AKI; however, mounting evidence has challenged this paradigm [ 29 , 30 ].…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…Infections, sepsis, shock, need for mechanical ventilation, and surgery are well recognized as high-risk factors for the development of AKI [ 28 ]. Sepsis has been reported to account for approximately 50% of patients with AKI in ICU, and it has been hypothesized that the modulation of proinflammatory cytokines in septic AKI might be beneficial [ 8 , 15 ]. Sepsis mediated hypoperfusion leading to tubular necrosis traditionally has been cited as the primary pathophysiology for SA-AKI; however, mounting evidence has challenged this paradigm [ 29 , 30 ].…”
Section: Discussionmentioning
confidence: 99%
“…The complications of AKI include increased susceptibility to infections, extrarenal organ damage, the development of CKD, and an increased rate of hospital readmission. NGAL, both in serum and urine, fulfills many of the characteristics important for a useful AKI biomarker and used in early diagnosis, which predicted mortality in not only all-cause AKI but also SA-AKI [ 11 – 15 ]. The results of this study can be simply understood that NGAL indirectly evaluates kidney damage, as NGAL increases mean severe kidney damage.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation