Serum myoglobin in acute cerebrovascular diseases.

Abstract

Concentration of myoglobin in serum was measured from 114 patients with acute cerebrovascular diseases and compared with serum creatine phosphokinase (CPK) and aldolase activities. The results obtained were as follows : (1) Elevated activity of myoglobin was observed in various types of stroke as well as CPK and aldolase. (2) The myoglobin level was significantly higher in patients with thalamic hemorrhage than in those with cortical infarction, while no difference was observed in other types of stroke. (3) The level of myoglobin was correlated well with the CPK level, but not with aldolase. (4) Correlation between myoglobin and level of consciousness was not observed. (5) No difference in myoglobin concentration in patients was observed between the died within four weeks and the survived. These results indicated that measurement of serum myoglobin in acute cerebrovascular diseases would not be useful for determining the type, severity and prognosis of the diseases.

ECG Changes in 8-Year-Old Boy with Pulmonary Edema after Head Injury

“…In addition to echocardiography and other invasive methods revealing centrally mediated myocardial dysfunction, there are few biochemical parameters (markers of myocardial damage) proving this. Today, the rise in serums myoglobin and creatinin phosphokinase -myocardial fraction isoenzyme (CPK-MB) is well confirmed in CNS disorders [6,7]. Stopfkuchen found high serum CPK-MB values in children with isolated head injury [8].…”

Prognostic significance of admission levels of cardiac indicators in patients with acute ischaemic stroke: Prospective observational study

“…10 In contrast to the viewpoint that elevated creatine kinase-MB levels represent biological markers for stroke-related myocardial injury, 8 creatine kinase-MB elevations in stroke patients may be noncardiac in origin. 11 Studies 12,13 have found elevated myoglobin levels in patients with all types of acute stroke, however, data regarding the value of the myoglobin level as a prognostic indicator of cardiac complications and the short-term outcomes of acute ischaemic stroke remain limited.…”

“…11 Studies 12,13 have found elevated myoglobin levels in patients with all types of acute stroke, however, data regarding the value of the myoglobin level as a prognostic indicator of cardiac complications and the short-term outcomes of acute ischaemic stroke remain limited.…”