Serum Levels of Interleukin (IL)-10, IL-17, Transforming Growth Factor (TGF)-β1, and Interferon-γ Cytokines and Expression Levels of IL-10 and TGF-β1 Genes in Renal Allograft Recipients After Donor Bone Marrow Cell Infusion

Effect of Rapamycin and Interleukin-2 on Regulatory CD4+CD25+Foxp3+ T Cells in Mice After Allogenic Corneal Transplantation

“…38,39 Moreover, they had close relationship with the allograft's function. 40 Combining previous findings, we deduced that the expanded Tregs induced by RAPA, IL-2, or the combination of both exerted their protective effect on the allograft at least partially through the increased secretion of IL-10 and TGF-␤1, just as the current study showed.…”

Immunological biomarkers of tolerance in human kidney transplantation: An updated literature review

“…We also demonstrated that infused patients possessed a higher ratio of IL‐10/IFN‐γ‐producing cells than noninfused patients using enzyme‐linked immunosorbent assay spot analysis (Ranjbar et al, ). However, this study and our other studies showed that DBMCs infusion decreased acute rejection episodes and increased patients’ survival (Mohammadnia et al, ; Solgi et al, ).…”

Five-year clinical effects of donor bone marrow cells infusions in kidney allograft recipients

“…At the same time, serum levels of inflammatory cytokines were also slightly lower in DBMC-infused patients. 24 With respect to peripheral microchimerism, a significantly higher frequency of patients testing positive for and with higher mean concentrations of microchimerism were observed in the DBMC-infused patients compared with controls during first year post operatively. Moreover, Stable graft function was correlated with both presence and concentrations of microchimerism, despite the small numbers of patients evaluated in the trial.…”

“…This became also statistically significant second year and quantification of peripheral microchimerism during first year after transplant have been described. 4,[23][24][25][26] Here we presented extended follow-up on this trial.…”