Serum concentrations of Cu, Zn, Fe, Mo and Co in newborn lambs following systemic administration of Vitamin E and selenium to the pregnant ewes

Kojouri, Gholam Ali; Shirazi, Azam Arsanjani

doi:10.1016/j.smallrumres.2006.02.002

Cited by 22 publications

(11 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the previous study, the levels of various trace elements were compared in newborn lambs following systemic administration of Se and vit E to pregnant ewes [10]. In contrast to our results, increasing levels of iron, and copper were seen during 4 weeks after birth but zinc level was only significantly higher at week 4 in test lambs than controls.…”

Section: Discussioncontrasting

confidence: 97%

See 1 more Smart Citation

Parenteral Selenium and Vitamin E Supplementation to Lambs: Hematology, Serum Biochemistry, Performance, and Relationship with Other Trace Elements

Mohri

Ehsani

Norouzian

et al. 2010

Biol Trace Elem Res

View full text Add to dashboard Cite

Most regions in Iran are generally selenium (Se) deficient and all mineral premixes which used in farm animals contain Se in the form of sodium selenite. The objective of this study was to evaluate the effects of injected Se and vitamin E (vit E) on hematology, serum proteins, and performance of lambs during the period which the animals are at risk of Se and/or vit E deficiency. The study also aims to determine the relationship between selenium injection and the levels of other trace elements in blood serum of lambs. A total of 16 lambs of Baloochi breed (age, 70 ± 7 days and weight, 15.2 ± 1.4) were enrolled in the study. The animals were divided into two groups. In the test group, vit E and Se injected at a dose of 0.2 ml/kg BW (Vetoquinol, Selepherol®, Lure Cedex, France, α-tocopherol acetate 3.82 g/100 ml plus sodium selenite 0.023 g/100 ml) at the enrollment. Control lambs were received equal amounts of normal saline as placebo. Blood was sampled from the jugular vein at the beginning of the study (enrollment, before injection of vit E and selenium and saline) and at days 7, 14, 21, and 28 of experiment. The amounts of total serum protein, albumin, glucose, iron, copper, zinc, creatine kinase (CK), and aspartate aminotransferase (AST) and Se were measured. The concentration of globulin was calculated as the difference between total serum protein and albumin. For evaluation of growth and health, body weight of all the lambs was measured at day 0 of the experiment and the sampling times and days of treatment for each lamb were recorded. Treatment with Se and vit E decreased the activities of CK and AST compared to the controls (p < 0.05). Age (sampling time) had significant effects on the values of Se, iron, zinc, AST, hemoglobin, total protein, glucose, weight, height, and length (p < 0.05). Significant interactions between sampling time and group were seen for CK, AST, iron, glucose, weight, and length. No significant differences were seen for total weight gain (control, 3.48 ± 0.75 kg; test, 3.85 ± 0.9 kg), and average daily gain (control, 0.12 ± 0.03 kg; test, 0.14 ± 0.03 kg) between trial groups.

show abstract

Section: Discussioncontrasting

confidence: 97%

“…The importance and roles of Se, selenoproteins, and vit E in muscle function and other veterinary important viewpoints were presented [5][6][7][8][9]. However, beneficial effects of nutritional or parenteral administration of vit E and Se have not been universal among studies [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Parenteral Selenium and Vitamin E Supplementation to Lambs: Hematology, Serum Biochemistry, Performance, and Relationship with Other Trace Elements

Mohri

Ehsani

Norouzian

et al. 2010

Biol Trace Elem Res

View full text Add to dashboard Cite

show abstract

“…Using both 35 and 70 ppm Zn as zinc sulphate and35 ppm Zn as Zn propionate in crossbreed bulls diet had a significant effect on semen volume, sperm properties and serum testosterone concentration compared with control (Kumar et al 2006). Some reports indicated the inhibition of zinc absorption from diet low in zinc, when selenium was high in selenoferous regions or a high Se supplement administration (Underwood 1999;Kojouri and Shirazi 2007;Moeini et al 2010;Moeini et al 2011). A positive correlation between serum Se concentration with Cu levels and a negative correlation between Se and Zn in treated animal has been reported (Kojouri and Shirazi 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Some reports indicated the inhibition of zinc absorption from diet low in zinc, when selenium was high in selenoferous regions or a high Se supplement administration (Underwood 1999;Kojouri and Shirazi 2007;Moeini et al 2010;Moeini et al 2011). A positive correlation between serum Se concentration with Cu levels and a negative correlation between Se and Zn in treated animal has been reported (Kojouri and Shirazi 2007). Also Kachuee et al (2013) concluded that the Zn status should be monitored when a high dose of Se is offered to animal.…”

Section: Introductionmentioning

confidence: 99%

Influences of dietary selenium, zinc and their combination on semen characteristics and testosterone concentration in mature rams during breeding season

Ghorbani

Moeini

Souri

et al. 2017

Journal of Applied Animal Research

View full text Add to dashboard Cite

2018) Influences of dietary selenium, zinc and their combination on semen characteristics and testosterone concentration in mature rams during breeding seasonABSTRACT This study was conducted to determine the effect of dietary supplementation of organic zinc (Availa®Zn100) and selenium (Availa®Se1000) on semen characteristics, testes measures and serum testosterone concentration. Twenty Sanjabi rams (50.01 ± 5.6 kg) were randomly divided into four equal groups, given the basal diet as control (C) or supplemented with 0.3 mg/kg Se (SE) or 40 mg/kg Zn (ZN) or 40 mg/kg Zn plus 0.3 mg/kg Se (ZS) for 120 days experiment (from July to November). The semen samples and blood samples were collected every 3 weeks and scrotal circumference was measured every 15 days. The results indicated that scrotal circumference and testosterone concentrations did not differ due to treatment (P > .05). In contrast, semen characteristics were affected by ZS supplementation. The sperm density and total sperm number increased (P < .05) in ZS group. In addition, the progressive sperm motility was higher in ZS (P < .05) than those of SE and C groups. It is concluded that ZS treatment can improve semen characteristics, which may result in overall improvement in reproductive performance of treated Sanjabi rams during the breeding season. ARTICLE HISTORY

show abstract

“…Cristaldi et al [13] reported that supplementation of Se to sheep increased copper absorption, whereas Kojouri and Shirazi [14] observed disturbed Cu/Zn and Zn/Fe ratios under the influence of Se, leading to zinc deficiency in young animals. On the other hand, Se deficiency leads to increased iron absorption, thus disturbing the distribution of other bioelements [15].…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Selenium and Selected Heavy Metals Concentration in Serum of Cattle from a Non-Polluted Area

Tomza–Marciniak

Pilarczyk

Bąkowska

et al. 2011

Biol Trace Elem Res

View full text Add to dashboard Cite

The present study was undertaken to evaluate the concentration of selenium and selected heavy metals and their possible relationship in serum of 25 healthy lactating cows (Montbéliarde) reared in a non-polluted area, in the western part of Poland. Cadmium, lead, copper, and zinc concentrations were determined by inductively coupled plasma-atomic emission spectrometry and Se concentration was determined fluorimetrically. The content of Se, Zn, and Cu was 0.083 ± 0.026, 0.629 ± 0.413, and 0.152 ± 0.042 μg/mL, respectively. The presence of the Cd and Pb was found in all serum samples. The mean concentration of these metals was 0.0009 ± 0.0008 and 0.018 ± 0.016 μg/mL, respectively. Analysis of correlations between Se and toxic metals showed a negative and significant (P < 0.05) relationship between selenium concentration and lead and cadmium concentration in the serum of the animals studied, with correlation coefficients of r = -0.595 and r = -0.618, respectively. For copper and zinc, this relationship was also negative but not significant (r = -0.255 and r = -0.203). Our study demonstrated that the level of toxic metals decreased as serum selenium concentration increased. It seems necessary to conduct further research on the interactions between these elements in blood, serum, and target organs concomitantly with the determination of their intake.

show abstract

Serum concentrations of Cu, Zn, Fe, Mo and Co in newborn lambs following systemic administration of Vitamin E and selenium to the pregnant ewes

Cited by 22 publications

References 2 publications

Parenteral Selenium and Vitamin E Supplementation to Lambs: Hematology, Serum Biochemistry, Performance, and Relationship with Other Trace Elements

Parenteral Selenium and Vitamin E Supplementation to Lambs: Hematology, Serum Biochemistry, Performance, and Relationship with Other Trace Elements

Influences of dietary selenium, zinc and their combination on semen characteristics and testosterone concentration in mature rams during breeding season

Relationship Between Selenium and Selected Heavy Metals Concentration in Serum of Cattle from a Non-Polluted Area

Contact Info

Product

Resources

About