Serum CA-125 in Preoperative Patients at High Risk for Endometriosis

Cheng, Ya-Min; Wang, Shan‐Tair; Chou, Cheng‐Yang

doi:10.1097/00006250-200203000-00003

Cited by 34 publications

(47 citation statements)

References 15 publications

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“…In this study, mean serum CA125 levels were greater in cases of adenomyosis or endometriosis, consistent with the findings from most previous studies [12][13][14][15][16][17]. However, previously published studies noted that CA125 was significantly higher in groups with endometriosis, whereas in our study, elevated CA125 levels were more significantly associated with adenomyosis than with endometriosis.…”

Section: Commentsupporting

confidence: 91%

“…However, previously published studies noted that CA125 was significantly higher in groups with endometriosis, whereas in our study, elevated CA125 levels were more significantly associated with adenomyosis than with endometriosis. The diagnosis of endometriosis in previous studies was based on results from laparoscopic observation and was not pathologically confirmed [15][16][17]. Conversely, diagnoses in our study were determined pathologically using total hysterectomy specimens.…”

Section: Commentmentioning

confidence: 83%

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Usefulness of CA125 in the differential diagnosis of uterine adenomyosis and myoma

Kil

Chung

Pak

et al. 2015

European Journal of Obstetrics & Gynecology and Reproductiv

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Section: Commentsupporting

confidence: 91%

Section: Commentmentioning

confidence: 83%

Usefulness of CA125 in the differential diagnosis of uterine adenomyosis and myoma

Kil

Chung

Pak

et al. 2015

European Journal of Obstetrics & Gynecology and Reproductiv

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“…Thus, the use of murine models to study disease processes in which the omentum plays a major role, such as postoperative adhesion formation (Ellis 1962;Ryan et al 1971), cancer metastasis (Okamura et al 2000;Sakurai et al 2001;Kodera et al 2002), sclerosing peritonitis (Clement et al 1994;Stenram 1997;Zareie et al 2003), and endometriosis (Grouls and Berndt 1995;Cheng et al 2002), may be justified. However, our results also raise important questions, such as the embryological origin/development of the fenestrations in the translucent region of the omentum and whether these structures play a role in its success as a graft material or its involvement in peritoneal pathology.…”

Section: Discussionmentioning

confidence: 99%

A comparative study of the structure of human and murine greater omentum

et al. 2005

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In humans, the greater omentum is a fatty peritoneal fold that extends from the greater curvature of the stomach to cover most abdominal organs. It performs many functions, which include acting as a reservoir of resident peritoneal inflammatory cells, a storage site for lipid, and a regulator of fluid exchange in and out of the peritoneal cavity. Most importantly, the omentum readily adheres to areas of inflammation and peritoneal damage, often leading to adhesion formation. Despite its clinical importance, the omentum remains an understudied organ, and discrepancies exist as to its exact morphology. This study uses a combination of phase contrast microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM) to elucidate the structure of the greater omentum of both human and mouse and determine whether it possesses a typical surface mesothelial cell lining similar to other serosa. Results indicated that both human and murine omenta were of similar structure and composed of two distinct types of tissue, one adipose-rich and the other translucent and membranous. The adipose-rich regions were well-vascularised and covered by a continuous mesothelial cell layer except at the sites of milky spots. In contrast, translucent areas were poorly vascularised and contained numerous fenestrations of varying size. The possible function and developmental origin of these gaps is unclear; however, their role in promoting omental adhesion formation and in the successful use of omental graft material is discussed.

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“…In the present study, the reference value used for endometriosis was Յ18 IU/mL (9). This value was chosen to increase the sensitivity for the diagnosis of mild (stage II) endometriosis as defined by the American Society for Reproductive Medicine (ASRM).…”

mentioning

confidence: 99%