Serum 25-hydroxyvitamin D levels in restless legs syndrome patients

Balaban, Hatice; Yıldız, Özlem; Çil, Gülsüm; Şentürk, İlteriş Ahmet; Erselcan, Taner; Bolayır, Ertuğrul; Topaktaş, Suat

doi:10.1016/j.sleep.2012.04.009

Cited by 58 publications

(61 citation statements)

References 41 publications

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“…The mean serum 25-hydroxyvitamin D levels were 7.31±4.63 ng/ml in female patients with RLS and 12.31±5.27 ng/mL in female control subjects (P=0.001). A significant inverse correlation between the vitamin D levels and disease severity of RLS was found in females (P=0.01, r=−0.47) [11]. Our study confirms the findings of Balaban et al although the sample size in our study was not large enough to show any gender difference.…”

Section: Discussionsupporting

confidence: 88%

“…Our results shed light on the possibility that the prevalence of RLS in the Saudi population may be greater than that recognized in clinical practice. Unfortunately, the local data regarding the prevalence of RLS among Saudi [11]. In their study, serum 25-hydroxyvitamin D levels in 36 female patients with RLS were measured and compared with those of 38 female healthy control subjects.…”

Section: Discussionmentioning

confidence: 99%

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The effect of vitamin D supplements on the severity of restless legs syndrome

et al. 2014

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

The effect of vitamin D supplements on the severity of restless legs syndrome

et al. 2014

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“…In a study conducted on 79 patients with iron deficiency, 58% of patients had 25 (OH) vitamin D levels of < 30 ng/ml whereas 39% had levels of < 20 ng/ml [29]. In a study conducted by Balaban et al, ferritin levels between the groups with and without RLS were also found different, and ferritin levels were found lower in the women patients with RLS [25]. In a study conducted by Zbroch et al, dialysis (75 hemodialyses and 26 peritoneal dialyzes) patients were included in the study and dopamine levels of patients were low [30].…”

Section: Resultsmentioning

confidence: 93%

“…Vitamin D metabolism disorders are commonly seen in chronic kidney diseases (CKD). Vitamin D synthesis is related to the failure of turning 25 [5]. In conducted studies, CKD is indicated as the secondary reason of RLS.…”

Section: Introductionmentioning

confidence: 99%

The relationship between restless leg syndrome and 25-hydroxy D vitamin in hemodialysis patients

Hüzmelí¹

2018

Ann Clin Anal Med

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Patients were asked about the diagnosis criteria of the International RLS study group and their laboratory examinations along with 25 (OH) D vitamin levels were assessed. Results: Seventy-five patients, 40 of whom were female, were included in the study. The average age of patients was 57.8 (19-84). Average 25 (OH) vitamin D levels of 75 patients in total were found to be 12.6 ±6.27 (3-30). Five patients had 25 (OH) D vitamin insufficiency and 70 had 25 (OH) D vitamin deficiency. Thirty-three patients were diagnosed with RLS and their average vitamin D levels were 10.76 ±4.56; the D levels of 42 patients not diagnosed with RLS were found to be 14.18±7.02. A significant relationship was determined between the patients diagnosed with RLS and their vitamin D levels (p=0.018).Discussion: A significant relationship was determined between RLS and 25 (OH) vitamin D level among hemodialysis patients. The fact that frequency of RLS was higher among hemodialysis patients compared to the general population may be related to low levels of 25 (OH) D vitamin.

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“…Restless leg syndrome (RLS), another SDB, was found to be more frequent and more severe in in adults with vitamin D deficiency [140][141][142] and it has a negative effect on sleep parameters [8]. Vitamin D supplementation was found to improve the severity of RLS [143].…”

Section: Vitamin Dmentioning

confidence: 99%

Nocturnal Enuresis in Children and Adolescent with Sickle cell Anemia

Ahmed¹

2017

Med Surg Urol

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Children with sickle cell anemia (SCA) have a tendency to have nocturnal enuresis (NE) more than normal children with males being more affected than females. Mechanisms of NE that operate in normal children probably do so in children with SCA. Postulated causes of nocturnal enuresis in individuals with SCA include hyposthenuria causing nocturnal polyuria, reduced bladder capacity or nocturnal bladder overactivity, sleep disordered breathing and an increased arousal thresholds. The variation in the reported prevalence rate of NE in SCA is probably due to differences in definition criteria and methodology. This review will discuss the prevalence rate and postulated causes of NE in children with SCA.

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Serum 25-hydroxyvitamin D levels in restless legs syndrome patients

Cited by 58 publications

References 41 publications

The effect of vitamin D supplements on the severity of restless legs syndrome

The effect of vitamin D supplements on the severity of restless legs syndrome

The relationship between restless leg syndrome and 25-hydroxy D vitamin in hemodialysis patients

Nocturnal Enuresis in Children and Adolescent with Sickle cell Anemia

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