2012
DOI: 10.1590/s0102-09352012000600001
| View full text |Cite
|
Sign up to set email alerts
|

Abstract: This study aimed to determine the power of the serum aspartate aminotransferase (AST) and gammaglutamyltransferasase (GGT) activities and of the albumin and cholesterol dosages for detecting hepatic histopathological injuries. A total of 220 healthy male Nelore cattle that had been extensively bred were evaluated. Blood and liver samples were collected on the day of slaughter for biochemical and histopathological tests. The results showed that the sensitivity to AST, GGT, albumin, and cholesterol tests were re… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

2
7
0

Year Published

2019
2019
2023
2023

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 12 publications
(9 citation statements)
references
References 10 publications
2
7
0
Order By: Relevance
“…The enzymatic changes observed in the blood serum of both groups, particularly of the GGT and GLDH enzymes, confirm liver impairment in animals with foreign body syndrome with or without cardiac involvement. This study confirms the measurement of serum GGT activity in cattle because it has greater specificity in detecting chronic liver injuries (Moreira et al, 2012). The magnitude of GLDH activity observed in animals in both groups confirms liver damage, since this enzyme is considered hepatospecific, being an important indicator of liver necrosis in ruminants (Hoffman & Solter, 2008).…”
Section: Blood Biochemistrysupporting
confidence: 76%
“…The enzymatic changes observed in the blood serum of both groups, particularly of the GGT and GLDH enzymes, confirm liver impairment in animals with foreign body syndrome with or without cardiac involvement. This study confirms the measurement of serum GGT activity in cattle because it has greater specificity in detecting chronic liver injuries (Moreira et al, 2012). The magnitude of GLDH activity observed in animals in both groups confirms liver damage, since this enzyme is considered hepatospecific, being an important indicator of liver necrosis in ruminants (Hoffman & Solter, 2008).…”
Section: Blood Biochemistrysupporting
confidence: 76%
“…Biochemical blood indicators, like the activity of some liver enzymes such as aspartate aminotransferase (AST, EC 2.6.1.2) and gamma-glutamyl transferase (GGT, EC 2.3.2.2) in blood serum, are used for the evaluation of metabolic balance [ 7 ]. The hepatic enzymes such as AST and GGT are the two main, sensitive enzymes that primarily reflect hepatocellular necrosis, and cholestasis, respectively, so are proposed to be two of the common parameters for the detection and diagnosis of liver failure [ 8 , 9 ]. The biochemical tests evaluated showed larger specificity than sensitivity regarding the detection of hepatic injuries in healthy dairy cattle.…”
Section: Introductionmentioning
confidence: 99%
“…Regarding the hepatic status, clinical biochemistry may correspond to a change, but it does not reveal the causes, types, or the distribution of the injury. Thus, histopathological analysis is essential to obtain consistent information about the hepatic histopathology (Moreira et al, 2012). In this context, results of AST and ALT corroborate the mild changes observed in the group treated with dry leaf extract (DL).…”
Section: Biochemical Analyses Of Alt and Astmentioning
confidence: 63%