Serous Otitis Media in Children

Abstract

We observed a high rate of culture positivity for A. otitidis in patients with clinical OME without suppuration. Further studies are needed to confirm whether the association of A. otitidis with OME represents causality. Antibiotic therapy aimed at A. otitidis is complicated by reported resistance, thus emphasizing the importance of our understanding of the pathogenetic role played by this organism

Concurrent Assay for Four Bacterial Species IncludingAlloiococcus Otitidisin Middle Ear, Nasopharynx and Tonsils of Children with Otitis Media with Effusion: A Preliminary Report

“…However, previous in vitro and in vivo studies demonstrated that this bacterium had an immunostimulatory capacity, and this indicated that it was not included in the normal flora of the middle ear cavity (15-21). This suggestion was also supported by de Miguel Martinez et al (12). In their study, A. otitidis was investigated in children with OME and acute otitis media, where the control group had a cochlear implant and did not have otitis for the previous 6 months.…”

“…Thus, it can result in developmental impairment of linguistic, behavioral, motor and social skills (1, 11, 12). …”

“…In their study, A. otitidis was investigated in children with OME and acute otitis media, where the control group had a cochlear implant and did not have otitis for the previous 6 months. The bacterial analysis was performed by means of microbiological culture-specific techniques and the cultures presented negative results in all cases of the control group (12). In our study, A. otitidis was detected alone in 7 out of 12 (58%) cases and it was identified together with one of the other three pathogens in 5 out of 12 (41.7%) cases.…”

“…de Miguel Martinez and Macias (12) reported that A. otitidis was sensitive to ampicillin and cefotaxime, but it was resistant to macrolides and cotrimoxazol. Harimaya et al (5) reported that A. otitidis was frequently detected in patients who received a beta-lactam antibiotics or erythromycin.…”

Reviewing the Pathogenic Potential of the Otitis-Associated Bacteria Alloiococcus otitidis and Turicella otitidis

“…When first discovered, A. otitidis was reported not to be found in the EAC (Faden and Dryja, 1989), but both A. otitidis and T. otitidis have since been proposed as members of the normal EAC flora. Both organisms have been observed in the EACs of healthy adults and children (Stroman et al, 2001;Frank et al, 2003;Tano et al, 2008;De Baere et al, 2010), indicating that they are capable of growth in the EAC without causing disease. Given this finding, it becomes important to establish whether the detection of A. otitidis and T. otitidis in MEF is a result of contamination during sampling, or if they inhabit both sites.…”