Serous Detachment of the Macula Associated With Presumed Choroidal Nevi

Choroidal (Subretinal) Neovascularization Secondary to Choroidal Nevus and Successful Treatment with Argon Laser Photocoagulation

“…Therefore, neovascularization or even an exudative disciform detachment overly ing a nevus, should not be regarded as the sine qua non of malignant change in a nevus [2,8,12], White/ left eye with 2 months hyperfluorosxenon photo-resolution of the female one and one half history' meta-cence in area coagulation the serous disc diameter morphopsia nasal to the retinal size elevated pig-with dctumor corresdetachment mented lesion of creased visual ponding to depigthe choroid loacuitylefteye mentation of the cated on the su-(20/50); dense RPE over a longperrotemporal scotoma standing retinal edge of the left superior to detachment; macula; small fixation with hypo fluorescence drusen and irrerelative of orange piggular orange pig-scotoma ment and staining ment over the sur-centrally of the subretinal face of the tumor; space secondary a serous retinal detachment ex tending nasally from the lesion to the macula to serous fluid An additional complication in the natu ral history of choroidal nevi arises when alterations occur in the retinal pigment epi thelium with resultant fluid leakage and sen sory elevation [2,3,5,6], A picture similar to central serous chorioretinopathy may be observed with nevus-induced foveal retinal pigment epithelial (RPE) leak and fluid ac cumulation. In contrast, however, to central serous chorioretinopathy which usually shows a single retinal pigment epithelial leak, choroidal nevi often cause multiple or diffuse leaks of the pigment epithelium [5], It is proposed that nevi are responsible for cho roidal insufficiency, a stimulus for drusen formation and associated sites of RPE leak age [3], Naumann et al [2] have observed a narrowing or localized obliteration of the choriocapillaris on fluorescein angiograms in one third of choroidal nevi.…”

“…Inadvertent burns to the fovea, retinal striae with macular fibrogliosis, and subretinal hemorrhage may re sult. Rebound or stimulation of neovascular proliferation may result following laser ther apy for neovascularization with choroidal nevi [5].…”

“…These include choroidal neovascularization [1], secondary changes in the overlying choriocapillaris [1][2][3], breaks in Bruch's membrane [4], drusen [1][2][3][4], retinal pigment epithelial de tachment [1,3,5], intraretinal deposits of white granular nonfluorescent material [3], serous detachment of the sensory retina. [1,[3][4][5][6][7], and visual field defects [2,4,6,8], ¡nation at that time revealed a visual acuity ol'20/400 in the right eye and 20/30 in the left eye.…”

Subretinal Choroidal Neovascularization Associated with Choroidal Nevus

“…C h o roidal nevi can be responsible for loss of visual acuity by inducing serous retinal detachment and degeneration of photoreceptors, combined with modifications of pigment epithelium cells, or by inducing a c h o roidal neovascularization (1,5,10,(18)(19)(20). P roliferation of a choroidal neovascularization on the surface of a nevus is a rare event, and only about 50 well-documented cases, describing the various clinical features of this complication, have been published (1, 3-11, 13, 18, 21).…”

Aktuelle Diagnostik bei choroidalen Nävi

“…der neurosensorischen Retina in dem betroffenen Bereich auf. Subretinale Flüssigkeit wird in 2-10,3 % beschrieben [5,18]. Fluoreszenzangiografisch sieht man die typischen Veränderungen, wie eine lokalisierte oder diffuse Leckage, in dem betroffenen Areal, bedingt durch die chronisch-degenerativen RPE-Veränderungen [18,19].…”