Aktuelle Diagnostik bei choroidalen Nävi

Lüke, Julia; Grisanti, Salvatore; Tura, Aysegül

doi:10.1055/s-0043-102592

Cited by 3 publications

(1 citation statement)

References 80 publications

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“…Histologically, a nevus is composed of benign cells (i.e., atypical melanocytes). A choroidal nevus is not a congenital condition and most often is acquired ( 23 ). Some studies indicate that a high estrogen level and high body mass index are important risk factors for choroidal nevi ( 24 ).…”

Section: Identification and Monitoring Of Choroid Nevusmentioning

confidence: 99%

Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas

Wang

Zhang

et al. 2021

Front. Oncol.

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Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset of such tumors is insidious, such that affected patients often have no pain or obvious discomfort during early stages. Notably, enucleation is required for patients with a severe choroidal melanoma, which can seriously impact their quality of life. Moreover, choroidal melanomas metastasize early, often to the liver; this eventually causes affected patients to die of liver failure. Therefore, early diagnosis of choroidal melanomas is extremely important. Unfortunately, an early choroidal melanoma is easily confused with a choroidal nevus, which is the most common benign tumor of the eye and does not often require surgical treatment. This review discusses recent advances in the use of multimodal and molecular imaging to identify choroidal melanomas and choroidal nevi, detect early metastasis, and diagnose patients with choroidal melanomas.

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Section: Identification and Monitoring Of Choroid Nevusmentioning

confidence: 99%

Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas

Wang

Zhang

et al. 2021

Front. Oncol.

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Potenziale und Limitationen der Detektion von zirkulierenden Melanomzellen

Lüke

Grisanti

Tura

2017

Klin Monatsbl Augenheilkd

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The detection and characterisation of circulating melanoma cells (CMC) is a non-invasive procedure with a low complication rate and can potentially distinguish choroidal nevi from uveal melanomas and help to initiate early adequate therapy. It has the perspective to select and monitor treatment. This technique may lead to new insights into the metastasis process itself and help to detect specific targets for future therapies. This article introduces the different techniques for CMC detection; their potentials and limitations are discussed.

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Potenziale und Limitationen der Detektion von zirkulierenden Melanomzellen

2018

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ZusammenfassungDie Bestimmung und Charakterisierung zirkulierender Melanomzellen ist ein nicht invasives und komplikationsarmes Verfahren mit dem Potenzial, einen choroidalen Nävus von einem choroidalen Melanom abzugrenzen und frühzeitig einer Therapie zuführen zu können. Zukünftig bietet es die Chance, das therapeutische Ansprechen zu überwachen und bei der Therapieauswahl zu helfen. Es besteht die Hoffnung, weitere Erkenntnisse hinsichtlich des Metastasierungsprozesses zu gewinnen und damit Ansatzpunkte für die Entwicklung zielgerichteter Therapien. In diesem Artikel werden die verschiedenen Techniken der Bestimmung zirkulierender Tumorzellen vorgestellt und ihr Potenzial bzw. Limitationen diskutiert.

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Aktuelle Diagnostik bei choroidalen Nävi

Cited by 3 publications

References 80 publications

Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas

Application of Multimodal and Molecular Imaging Techniques in the Detection of Choroidal Melanomas

Potenziale und Limitationen der Detektion von zirkulierenden Melanomzellen

Potenziale und Limitationen der Detektion von zirkulierenden Melanomzellen

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