Seroprevalencia de la enfermedad de Chagas y factores de riesgo asociados en una población de Morroa, Sucre

Hoyos, Richard; Pacheco-Lugo, Lisandro; Agudelo, Luz Adriana; Zafra, German; Blanco, Pedro; Triana, Omar

doi:10.7705/biomedica.v27i1.256

Cited by 13 publications

(8 citation statements)

References 16 publications

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“…This could be due to increased parasite replication rates at higher temperatures (Wood, 1954; Asin and Catalá, 1995). However, the insects in this study were reared under climate conditions similar to those found in R. prolixus -endemic areas of Colombia (Hoyos et al 2007; Gutierrez et al 2013), thus, if temperature were an underlying factor in T. cruzi virulence, it would suggest that T. cruzi may also be virulent to free-living Colombian R. prolixus .…”

Section: Discussionmentioning

confidence: 93%

Trypanosoma cruzi–Trypanosoma rangelico-infection ameliorates negative effects of single trypanosome infections in experimentally infectedRhodnius prolixus

et al. 2016

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Trypanosoma cruzi, causative agent of Chagas disease, co-infects its triatomine vector with its sister species Trypanosoma rangeli, which shares 60% of its antigens with T. cruzi. Additionally, T. rangeli has been observed to be pathogenic in some of its vector species. Although T. cruzi-T. rangeli co-infections are common, their effect on the vector has rarely been investigated. Therefore, we measured the fitness (survival and reproduction) of triatomine species Rhodnius prolixus infected with just T. cruzi, just T. rangeli, or both T. cruzi and T. rangeli. We found that survival (as estimated by survival probability and hazard ratios) was significantly different between treatments, with the T. cruzi treatment group having lower survival than the co-infected treatment. Reproduction and total fitness estimates in the T. cruzi and T. rangeli treatments were significantly lower than in the co-infected and control groups. The T. cruzi and T. rangeli treatment group fitness estimates were not significantly different from each other. Additionally, co-infected insects appeared to tolerate higher doses of parasites than insects with single-species infections. Our results suggest that T. cruzi-T. rangeli co-infection could ameliorate negative effects of single infections of either parasite on R. prolixus and potentially help it to tolerate higher parasite doses.

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Section: Discussionmentioning

confidence: 93%

Trypanosoma cruzi–Trypanosoma rangelico-infection ameliorates negative effects of single trypanosome infections in experimentally infectedRhodnius prolixus

et al. 2016

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“…The epidemiological role of this species in Colombia, Venezuela and Brazil is still unclear due to its low infection rate [19, 36, 37]. In this regard, this study provides the following evidence that highlights the epidemiological importance of this vector: (i) household-invading behavior in 12.8% of houses in the Mompos rural area and 6.8% in Talaigua Nuevo, (ii) higher seroprevalence and transmission in children under 15 years of age in areas with household-invading behavior (the Mompos rural area and Talaigua Nuevo), (iii) peridomiciliary infestation greater than 10% and (iv) a positive correlation between the presence of this species in houses with human seropositivity.…”

Section: Discussionmentioning

confidence: 99%

“…The epidemiological role for this species is not yet clear because it is usually reported without natural T. cruzi infection and there are no reports of active human transmission in areas where T. maculata is the only triatomine recorded [12, 19]. However, in Talaigua Nuevo (Bolivar Department, Colombia), T. maculata has been reported to harbor natural T. cruzi infection in an active transmission focus area [20].…”

Section: Introductionmentioning

confidence: 99%

Trypanosoma cruzi transmission in a Colombian Caribbean region suggests that secondary vectors play an important epidemiological role

et al. 2014

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BackgroundColombia, as part of The Andean Countries Initiative has given priority to triatomine control programs to eliminate primary (domiciliated) vector species such as Rhodnius prolixus and Triatoma dimidiata. However, recent events of Trypanosoma cruzi transmission in localities where R. prolixus and T. dimidiata are not present suggest that other species are involved in the T. cruzi transmission cycle.MethodsWe studied T. cruzi transmission on Margarita Island, located on the Magdalena River in the Colombian Caribbean region, where a high number of non-domiciliated triatomines infected with T. cruzi inside human dwellings have been observed. A cross-sectional survey including serological studies in humans and parasitological and molecular methods in vectors and reservoirs was conducted. We investigated risk factors for human infection and house infestation, and evaluated the association between abundance of wild triatomines in palm trees (Attalea butyracea) across municipalities, seasons and anthropogenic land use.ResultsThe T. cruzi seroprevalence rate in humans was 1.7% (13/743) and autochthonous active T. cruzi transmission was detected. The infection risk was associated with the capture of triatomines in human dwellings. Five wild mammal species were infected with T. cruzi, where Didelphis marsupialis was the main reservoir host with an 86.3% (19/22) infection rate. TcIb was the only genotype present among vectors. Triatomine abundance was significantly higher in Ecosystem 2, as well as in the dry season. Despite the absence of triatomine domiciliation in this area, T. cruzi active transmission was registered with a human seroprevalence rate similar to that reported in areas with domesticated R. prolixus.ConclusionsThis study illustrates the importance of secondary and household invading triatomines in Chagas disease epidemiology in the Caribbean lowlands of Colombia.

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“…Por otro lado, respecto a los factores asociados a la enfermedad de Chagas, se observó que un 92,4 % de la población reconoce al vector, 52,2 % lo ha visto en su domicilio o alrededores y 27,2 % de los encuestados han sido picados por el insecto, estas cifras se encuentran por encima de lo encontrado en el estudio realizado por Ciria et al en un municipio de México, donde los datos reportaron que un 33,33 % de la población ha visto al triatomino en casa y un 8,82 % afirmó haber sido picado 26 , al igual que en el estudio desarrollado por Carreño et al en Casanare Colombia, en el que un 33,3 % de la población conoce o ha oído hablar del vector y 60,6 % lo ha visto en el intra y peridomicilio 27 . En el ciclo epidemiológico de la enfermedad de Chagas, los animales reservorios de T.cruzi son un importante factor, dentro de ellos, los animales domésticos como los perros están expuestos a los triatominos por su circulación entre el domicilio y el peridomicilio, esto favorece al vector porque lo usa como su fuente de alimento y le permite acercarse y pasar a colonizar la vivienda 16 .…”

Section: Discussionunclassified

Conocimientos, actitudes y prácticas sobre la enfermedad de Chagas en una zona endémica de Boyacá, Colombia

López

Monroy-Díaz

Rodríguez³

et al. 2022

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Introducción: el uso de instrumentos para la obtención de información sobre los conocimientos, actitudes y prácticas de diversas enfermedades son ampliamente utilizados, permiten obtener información clara y detallada de cada uno de los aspectos a indagar. Objetivo: Determinar conocimientos, actitudes y prácticas de la enfermedad de Chagas en una zona endémica de Boyacá, Colombia. Métodos: Estudio transversal prospectivo que consistió en aplicar un instrumento validado que abordaba datos sociodemográficos, factores epidemiológicos, conocimientos, actitudes y prácticas de la enfermedad de Chagas en un integrante mayor de edad de 341 familias de Miraflores, Boyacá. Se emplearon escalas: óptimo, bueno, regular y malo; para el análisis bivariado se determinó el nivel de conocimientos, actitudes y prácticas con escala favorable y desfavorable. Se determinaron diferencias significativas de factores de riesgo, conocimientos, actitudes y prácticas de la enfermedad entre el grupo de hombres y mujeres encuestados. Resultados. El 68,6% de la población nació en Miraflores, con un 48% de escolaridad primaria y pertenecientes a la zona rural en su mayoría (57,2%); en las mujeres predomina la ocupación de ama de casa, en los hombres es más frecuente la agricultura. Se identificaron conocimientos (48,1%) y actitudes (82,1%) óptimas sobre la enfermedad de Chagas que minimizan el riesgo de contraer la infección por T. cruzi; paradójicamente, se encontraron malas prácticas (61,9%) en el hogar que no previenen la enfermedad. Se observó significancia respecto al nivel de escolaridad bajo, sexo femenino, ser menor de 49 años, vivir en zona urbana y actividades del hogar, todo lo anterior permite un conocimiento favorable acerca de la enfermedad de Chagas, aunque sin evidencia estadística. Conclusión: Se hace necesario incorporar programas que garanticen el aprendizaje y la implementación de actitudes y prácticas favorables contra la enfermedad en habitantes de zonas endémicas.

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Seroprevalencia de la enfermedad de Chagas y factores de riesgo asociados en una población de Morroa, Sucre

Cited by 13 publications

References 16 publications

Trypanosoma cruzi–Trypanosoma rangelico-infection ameliorates negative effects of single trypanosome infections in experimentally infectedRhodnius prolixus

Trypanosoma cruzi–Trypanosoma rangelico-infection ameliorates negative effects of single trypanosome infections in experimentally infectedRhodnius prolixus

Trypanosoma cruzi transmission in a Colombian Caribbean region suggests that secondary vectors play an important epidemiological role

Conocimientos, actitudes y prácticas sobre la enfermedad de Chagas en una zona endémica de Boyacá, Colombia

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