Seroprevalence of TORCH in women with spontaneous abortion and stillbirth, in Asmara, Eritrea

Abstract

INTRODUCTION Toxoplasma gondii, others, rubella, cytomegalovirus and herpes simplex (all together denoted as TORCH) are the major causes of bad obstetric history (BOH) and may cause birth defects. Therefore, antenatal screening for antibodies to TORCH infectious agents is an important tool for diagnosis. Thus, the study was conducted to determine the seroprevalence of TORCH among mothers with a loss of pregnancy (abortion) or stillbirth. METHODS A laboratory-based cross-sectional study on the frequency and associated risk factors for the prevalence of TORCH was conducted from 28 February to 31 March 2018. The study included 44 women aged 18-45 years who were admitted at Orotta Maternity National Referral and Teaching Hospital, Asmara, Eritrea, due to loss of pregnancy (abortion) or stillbirth. The study participants were selected by systematic random sampling. From each woman, 3 mL of venous blood was collected in a container with aseptic technique. Immunoglobulin G antibodies against Toxoplasma gondii, rubella, cytomegalovirus and herpes simplex were detected by IgG Combo Rapid Test Cassette (Serum). RESULTS Of the 44 mothers with mean age of 29.3 years (SD=5.6), who were tested by IgG Combo Rapid Test Cassette