Cytomegalovirus reactivation in a SARS-CoV-2 infected woman experiencing fetal demise in the first trimester with fetal trisomy 21: A case report

Pande, Shailesh; Gandhewar, Manisha; Gaikwad, P.D.; Shende, Prajakta; Munne, Kiran; Bhor, Vikrant M.; Das, Dhanjit Kumar; Bashani, Dolly; Bhase, Manasi; Rathore, Amisha; Shah, Karan; Gawde, Harshavardhan; Padwal, Varsha; Bhagat, Sharad; Menon, Shyla; Palav, Harsha; Sachdeva, Geetanjali; Patel, Vainav

doi:10.1016/j.ijmmb.2022.12.002

Cited by 1 publication

(2 citation statements)

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“…Coinfections with SARS-CoV-2 and other pathogens, such as viruses, bacteria, and fungi, have been reported; however, most of these viruses are respiratory [12][13][14][15][16]. Few cases of CMV coinfection with SARS-CoV-2 in mild COVID-19 (i.e., without pneumonia or respiratory failure) have been reported in immunocompromised patients, such as those with acquired immunodefciency syndrome, hematologic malignancy, kidney transplant recipient, or a pregnant woman [17][18][19][20]. CMV coinfection with SARS-CoV-2 in mild COVID-19 cases in patients without serious medical conditions is very rare, and its incidence and clinical signifcance remain unclear.…”

Section: Discussionmentioning

confidence: 99%

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID- 19), which continues to threaten global health [1]. Safe and efective vaccines and treatment options are now available [2]; however, COVID-19 still causes hospitalization or death, especially in the elderly and in people with pre-existing conditions.…”

Section: Introductionmentioning

confidence: 99%

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Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19

Ura,

Goubaru,

Motoya

et al. 2023

Case Reports in Infectious Diseases

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Persistent fever due to coronavirus disease 2019 (COVID-19) is a considerable issue for patients and physicians that requires a broad differential diagnosis and evaluation of complications. Coinfections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and various respiratory viruses have also been reported. In severe cases of COVID-19, cytomegalovirus (CMV) reactivation or CMV coinfection with SARS-CoV-2 has been reported in association with critical illnesses and immunosuppressive therapy; however, in mild COVID-19 cases, CMV coinfection with SARS-CoV-2 has been reported only in severely immunocompromised patients, and its incidence and clinical importance remain unclear. Herein, we report a rare case of coinfection with SARS-CoV-2 and CMV in a patient with mild COVID-19 and untreated diabetes mellitus, which led to persistent fever for approximately 4 weeks. CMV coinfection should be considered in patients with COVID-19 who exhibit persistent fever.

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