Seroprevalence of low rubella IgG antibody levels among antenatal women in England tested by NHS Blood and Transplant: 2004–2009. Is rubella susceptibility increasing?

Byrne, Lisa; Brant, L. J.; Reynolds, Claire; Ramsay, Mary

doi:10.1016/j.vaccine.2011.11.045

Cited by 43 publications

(44 citation statements)

References 29 publications

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“…Recent studies in other European countries reported similar data: the prevalence observed in Norway was 94.4% [23] and in England between 94.9% [24] and 97.4% [25]. In the United States, the prevalence was 91.5% [26], while in Canada the prevalence was 93.2% in Canadian-born mothers but was lower in immigrants from Northern Africa, the Middle East, China and the South Pacific [27].…”

Section: Discussionsupporting

confidence: 59%

“…Increased travel to and from countries with circulating rubella, combined with social interaction with populations presenting lower levels of rubella-specific antibodies, may give rise to local outbreaks when protection falls below 90% [25,35]. In the present study, immigrant pregnant women presented greater susceptibility to rubella (7.6%) compared to those born in Spain (4.6%).…”

Section: Discussionmentioning

confidence: 50%

“…Higher susceptibility may also reflect a decline in the antibody levels from childhood vaccinations, as this cohort would have been eligible for two doses of rubella-containing vaccine, although data from surveillance of rubella and CRS suggest that waning immunity with increased susceptibility to rubella does not occur [10,25,32,33]. In 2012, Spanish national coverage of the first dose of MMR vaccine in infants was > 95%, but only 90% for the second dose [34].…”

Section: Discussionmentioning

confidence: 99%

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Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain

Vilajeliu

García‐Basteiro

Valencia

et al. 2015

Vaccine

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.4-1.8) were more likely to be susceptible. The second dose of MMR vaccine was received by 57.2% (718/1256) of rubella-susceptible women, with the highest proportion being immigrant women compared with women born in Spain. After vaccination, all women showed rubella immunity. Conclusions:The higher rubella susceptibility found in the three youngest age groups and in immigrant women highlights the relevance of antenatal screening, in order to ensure identification and postpartum immunization. The postpartum immunization strategy is an opportunity to protect women of childbearing age and consequently prevent occurrence of CRS, and to increase vaccination coverage against rubella and other vaccine-preventable diseases.

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Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 99%

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Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain

Vilajeliu

García‐Basteiro

Valencia

et al. 2015

Vaccine

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“…For the IBD patients at our institution, we measured specific antibody levels for MMR, and varicella using EIA, which has a high sensitivity and high versatility. In the present study, seronegativity rates for measles, mumps, rubella, and varicella were 32.5, 37.1, 32.0, and 5.1%, respectively, similar to the rates reported by Naganuma et al [5,6]. In addition, in a study on healthcare workers in major hospitals in Japan, in which seronegativity was defined as IgG < 4 IU/mL by the EIA method, the reported seronegativity rates were 7.4% for measles, 16.1% for mumps, 8.4% for rubella, and 0.8% for varicella [4,[7][8][9][10][11], and when we computed the seronegativity rates of our IBD patients using the same cutoff value, the rate was 3.0% for measles, 37.1% for mumps, 14.1% for rubella, and 5.1% for varicella, indicating higher seronegativity rates for healthcare workers in the general population were for IBD patients, with the exception of measles.…”

Section: Immunization Coverage In Japansupporting

confidence: 91%

Prevention of Infectious Diseases due to Immunosuppression and Vaccinations in Asian Patients with Inflammatory Bowel Disease

Sagami

Hibi

2018

Inflamm Intest Dis

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Background: Inflammatory bowel disease (IBD) patients with immunocompromise have a high risk of developing complications related to viral infections. Western countries were the first to formulate vaccine guideline. Asian countries developed their national and international vaccine guidelines a little later in order to reduce the risk of mortality from viral infections. However, no studies to date have examined the differences in vaccinations that prevail among Asian countries. Summary: This review summarizes the vaccination status and schedules in various Asian countries for immunocompromised IBD patients. Vaccination rates, regardless of the specific vaccine, were high in Japan, South Korea, and China and low in India and the Philippines. Vaccine schedules differed by country, and outbreaks of measles and rubella were seen due to low vaccination rates in Southeast Asia and South Asia. Live vaccines cannot be administered during immunosuppressive treatment. Infection with measles, mumps, and varicella during immunosuppressive therapy carries a high risk of mortality, and thus confirmation of immunization status is recommended as soon as IBD is diagnosed and, when possible, live vaccines should be administered before the initiation of immunosuppressive treatment. In patients seronegative for hepatitis B, administration of the hepatitis B vaccine is also recommended. Key Messages: Physicians, while considering severity of outbreaks, should understand the differences in vaccination status that exist among the various Asian countries and regions.

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“…In the United Kingdom, rubella vaccination started in 1970 and in one study, the frequency of women with anti-rubella IgG < 10 IU/mL increased by 60% over the 6-year study period [22]. In a survey in 1997 from 45 developing countries, the proportion of women who remained susceptible to rubella was < 10% in 13 countries (including the Islamic Republic of Iran, Oman, Kuwait, China, Chile, Saudi Arabia and Gambia) and 10%-24% in 20 countries and ≥ 25% in 12 countries (including Thailand, India, Malaysia, Singapore and Panama) [3].…”

Section: Discussionmentioning

confidence: 99%

What do we need to eradicate rubella in the Islamic Republic of Iran?

Almassinokiani

Noorbakhsh²,

Rezaei³

et al. 2013

East Mediterr Health J

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To evaluate the need for congenital rubella syndrome prevention in our national health programme we aimed to determine the rate of anti-rubella positivity in umbilical cord blood samples 8 years after measlesrubella mass vaccination in the Islamic Republic of Iran. In a cross-sectional study we tested umbilical cord blood samples for anti-rubella IgG and IgM by ELISA in 154 deliveries at a university hospital in Tehran. Overall 72.7% of umbilical cord blood samples were positive for anti-rubella IgG and 27.3% were negative. All of the samples were negative for anti-rubella IgM. In the samples with a history of mothers' rubella vaccination, only 87.5% were positive for anti-rubella IgG. The results suggest the need for another mass vaccination for rubella in women of child-bearing age and continuation of routine vaccination of infants, plus consideration of obligatory anti-rubella IgG testing before pregnancy in women who were not vaccinated and vaccination of women before marriage. RÉSUMÉ Pour évaluer la nécessité d'intégrer la prévention du syndrome de rubéole congénitale dans notre programme de santé national, nous avons tenté de déterminer le taux de positivité aux anticorps antirubéoleux dans des échantillons de sang de cordon ombilical huit ans après la campagne de vaccination de masse contre la rougeole et la rubéole en

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Seroprevalence of low rubella IgG antibody levels among antenatal women in England tested by NHS Blood and Transplant: 2004–2009. Is rubella susceptibility increasing?

Cited by 43 publications

References 29 publications

Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain

Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain

Prevention of Infectious Diseases due to Immunosuppression and Vaccinations in Asian Patients with Inflammatory Bowel Disease

What do we need to eradicate rubella in the Islamic Republic of Iran?

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