Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) among Pregnant Women Accessing Antenatal Care in a Tertiary Healthcare Facility in Central Nigeria

Oti, Victor B.; Usman, Bello; Pennap, G. R. I.; Eno-Ibanga, C

doi:10.9734/ajrimps/2017/37030

Cited by 5 publications

(12 citation statements)

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“…On the basis of age distribution, the outcome of this study shows that the prevalence of HSV-2 infection was non-significantly (P>0.05) higher among participants 16-20 years old than other age groups examined. This study differs from other previous studies that reported high prevalence rate of HSV-2 IgG and IgM antibodies mostly among under 5 years children [28] and in the elderly [29].…”

Section: Resultscontrasting

confidence: 99%

Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria

Enitan

Ihongbe

Ochei

et al. 2020

I-SRR

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Background: Herpes simplex virus type 2 (HSV-2) causes genital herpes, a chronic viral infection that is sexually transmitted and often results in genital ulcer disease (GUD) worldwide. Aim: The aim of this study was to determine the prevalence of herpes simplex virus type 2 (HSV-2) IgG and IgM antibodies and the associated risk factors among undergraduate female students of Babcock University. Methods: After ethical approval was obtained, serum samples of 150 consenting female participants (16-35 years) were collected randomly and screened using NADALR HSV-2 IgG/IgM Rapid Antibody Test Cassette (Bulgarian Company for Biotechnology, Sofia, Bulgaria). The demographic and clinical information of the participants were also collected using a structured questionnaire. The results were statistically analyzed using the SPSS version 18.0. Results: The outcome of the study shows that out of the 150 participants screened, 5 (3.3%) were positive for HSV-2 IgG antibody, 4 (2.7%) were positive for HSV-2 IgM; while 2 (1.3%) were positive for both HSV-2 IgG and IgM antibodies. There were no significant differences (P>0.05) in the seropositivity for HSV-2 IgG and IgM antibodies among the study participants on the basis of age distribution. With regards to clinical indication for genital herpes in relation to seropositivity of HSV-2 IgG and IgM antibodies among the study participants, none of the 7 (4.6%) who indicated vaginal itching was seropositive for either HSV-2 IgG or HSV-2 IgM or both. On the other hand, genital lesions were recorded in 0.7% HSV-2 IgG seropositive, 1.3% HSV-2 IgM seropositive and 0.7% HSV-2 both IgG and IgM seropositive. Genital ulcer was recorded among two participants who were either seropositive for HSV-2 IgG (0.7%) or HSV-2 IgM (0.7%). Only one (0.7%) participant indicated inguinal lymphadenopathy, however, the person was HSV-2 IgG/IgM seronegative. Identifiable risk factor significantly (P<0.05) associated with HSV-2 infection include: history of sexually transmitted infections, HIV positive status, and change of sex partners recently. Conclusion: The outcome of this study shows that HSV-2 infection exists among undergraduate female students of Babcock University, Nigeria and therefore appropriate public health measures must be taken to halt the cycle of infection within the University community. Early detection of genital herpes and prompt treatment will help prevent subsequent complications such as genital ulcer disease among young female adults.

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Section: Resultscontrasting

confidence: 99%

Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria

Enitan

Ihongbe

Ochei

et al. 2020

I-SRR

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“…Infection can occur at any age if exposed to the virus. This is also supported by Oti and colleagues [12]. However, age range of 20-24 recorded the highest prevalence (75 %, Table 1) in the present study.…”

Section: Discussionsupporting

confidence: 91%

“…The seroprevalence of the IgG is relatively high when they are compared with similar studies carried out in other States in Nigeria. There has been a report of 35.5 % seroprevalence in a tertiary health facility in central Nigeria [12]. Also record of 46.3 % seroprevalence among pregnant women in Benin, Nigeria [20] has been documented.…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of HSV infection is said to increase with age, with the highest around 40 years [11]. Furthermore, it has been reported that age, educational status, parity, stage of pregnancy and history of blood transfusion were not significantly associated with the viral prevalence [12]. This infection appears to be related to the number of sexual partners, and with respect togender, infection is said to be more frequent in women than in men [13].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of herpes simplex virus type 2 antibodies among pregnant women attending Federal Teaching Hospital, Ido-Ekiti, Nigeria

Oluwapelumi¹,

Peace²,

Akele³

et al. 2020

World J. Adv. Res. Rev.

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Herpes simplex virus type 2 (genital herpes) is mostly asymptomatic except if the immune system is compromised. However, infections could lead to preterm delivery, low infant birth weight, still birth, hydrops, cystic brain degeneration, and fetal growth retardation. Record of the prevalence of the viral infection is scanty among pregnant women in Ekiti State, Nigeria. This study was conducted to determine the prevalence of herpes simplex virus type 2 antibodies among pregnant women attending Federal Teaching Hospital Ido-Ekiti. Structured questionnaires were administered to obtain information such as age, incidence of miscarriages, marital status and number of pregnancies among the women who were examined. Ninety (90) pregnant women were examined for the presence of herpes simplex virus type 2 (HSV-2) IgG and IgM antibodies using enzyme linked immunosorbent assay (ELISA) technique. Prevalence of HSV-2 IgG and IgM antibodies among pregnant women was 64.4 % and 2.2 % respectively. A significant (p<0.05) number of the pregnant women recorded presence of IgG antibody to the virus. There was no statistical significant (p>0.05) difference between the prevalence of HSV-2 IgG antibody across age ranges, number of miscarriages, marital status and number of pregnancies. There may be need for antenatal screening of pregnant women for this virus in Ekiti State and perhaps generally in pregnancy to rule out the presence of genital herpes. With the risk of infection to fetus in mind, health policy makers may campaign against genital herpes to avert transmission of the virus to fetus before birth or after child birth.

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“…Education has been acknowledged to be of advantage in various facets of life. It helps in making informed decision and also sourcing for useful information regarding health status on possible ways of avoiding infectious agents [23]. This report is consistent with reports of Okoh and Omuemu, and Hussain et al which asserted that educational status has a statistically significant association with on HIV and HBV positivity [4,16].…”

Section: /4supporting

confidence: 87%

Parallel and Overlapping Infection of Human Immunodeficiency Virus and Hepatitis B Virus Among Tuberculosis Patients Attending A Tuberculosis/Leprosy Referral Centre in Central Nigeria: A Cross-Sectional Study

Gri¹,

Oti²,

Ca³

2018

J Transl Gastroenterol Clin Hepatol

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Tuberculosis (TB) is a global health problem. Coinfection with Human Immunodeficiency Virus (HIV) and Hepatitis B virus (HBV) among TB patients has paved way for the resurgence of Mycobacterium tuberculosis infection as well as increased risk of hepatotoxicity during tuberculosis therapy. There is paucity of published data on HIV/HBV infection in TB patients in Nigeria. This was a baseline study carried out to determine coinfection of HIV and HBV in Tuberculosis confirmed patients attending a TB/Leprosy referral healthcare Centre in Central Nigeria. Blood samples were collected from 400 confirmed TB patients and their sociodemograph information were obtained using a structured questionnaire. Samples were analyzed for anti-HIV and HbsAg using Enzyme Linked Immunosorbent Assay (J. Mitra and Co. Pvt. Ltd, India and Shantha Biotechnics Ltd, India respectively). Data were analyzed using SSP version 2.80. P value ≤ 0.05 was considered statistically significant. Of the 400 patients, 68(17.0%) tested positive for HIV and 48(12.0%) for HBV while 6 (1.5%) had HIV/HBV coinfection. Gender, history of STI, history of HBV vaccine and educational status were associated risk factors for the viral infection. Age, history of blood transfusion and scarification mark did not show any statistically significant association to the viral infections. The prevalence rates of HIV and HBV recorded in this population is a cause for alarm. There is therefore a need to introduce the monitoring of TB patients for therapyrelated hepatotoxicity and performance of these viral infections.

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Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) among Pregnant Women Accessing Antenatal Care in a Tertiary Healthcare Facility in Central Nigeria

Cited by 5 publications

References 0 publications

Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria

Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria

Prevalence of herpes simplex virus type 2 antibodies among pregnant women attending Federal Teaching Hospital, Ido-Ekiti, Nigeria

Parallel and Overlapping Infection of Human Immunodeficiency Virus and Hepatitis B Virus Among Tuberculosis Patients Attending A Tuberculosis/Leprosy Referral Centre in Central Nigeria: A Cross-Sectional Study

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