Seroprevalence of hepatitis viruses in children in rural Viet Nam

Katelaris, Peter; Robertson, Graham; Bradbury, Ross; Tippett, George; Hoa, Duong Quynh; Ngu, Meng C.

doi:10.1016/0035-9203(95)90077-2

Cited by 17 publications

(15 citation statements)

References 3 publications

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“…Universal infant HBV vaccination was only introduced in Thai Binh Province in 2000, and there are no specific HBV vaccination programs for adolescents or high-risk individuals. The positive trend in HBV prevalence with increasing age found in both our study and other Vietnamese studies 14,28 suggests ongoing HBV horizontal transmission. Previous Vietnamese urban-based studies have found associations between HBsAg and history of surgery, using reused syringes, dental procedures, acupuncture, sharing razors and having manicure at beauty shops.…”

Section: Discussionsupporting

confidence: 80%

Highly endemic hepatitis B infection in rural Vietnam

Nguyen

McLaws

Dore

2007

J of Gastro and Hepatol

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Section: Discussionsupporting

confidence: 80%

Highly endemic hepatitis B infection in rural Vietnam

Nguyen

McLaws

Dore

2007

J of Gastro and Hepatol

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“…1 Our population-based, age-stratified serosurvey of HBV markers in Vietnam 2 indicated a very high seroprevalence of HBV infection commencing early in life. It confirmed the findings of other published [3][4][5] and unpublished surveys, and highlighted the need for a program of immunization beginning at birth. However, delivery of vaccines to newborns in Vietnam is not easy because the rate of home birth is high (average ‫ס‬ 21.3%, and up to 56.1% in the northern highlands 6 ) and access of health workers in rural areas can be very difficult.…”

Section: Introductionsupporting

confidence: 88%

Immunogenicity of a Locally Produced Hepatitis B Vaccine With the Birth Dose Stored Outside the Cold Chain in Rural Vietnam

Hipgrave

Tran²,

Huong³

et al. 2006

Am J Trop Med Hyg

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The heat stability of hepatitis B vaccine (HepB vaccine) should enable its storage outside the cold chain (OCC), increasing access to the birth dose in areas lacking refrigeration. We compared the immunogenicity of a locally produced vaccine among infants who received three doses stored within the cold chain (n = 358) or for whom the first dose was stored OCC for up to one month (n = 748). Serum was collected from these infants at age 9-18 months. The vaccine was protective in 80.3% of all infants. There were no differences in the prevalence of a protective level of antibody or antibody titer among groups of infants according to storage strategy. Differences in antibody titer between certain groups of infants could be explained by different vaccination schedules. Where birth dose coverage will be improved, HepB vaccine can be taken OCC for up to one month without affecting its immunogenicity.

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“…Australian community‐based HBV seroprevalence studies among immigrants from APR countries are not available; however, studies conducted in several other countries including United Kingdom, Canada, and United States show HBsAg prevalence among Asian immigrants/refugees to be very similar to HBsAg prevalence in countries of origin 65–77 . For example, HBsAg prevalence among Vietnamese immigrants/refugees in these countries was 10.0–16.6%, 65–70 reflecting HBsAg prevalence in population‐based studies in Vietnam (10.0–19.5%) 17,18,31,78–86 …”

Section: Discussionmentioning

confidence: 99%