Seroprevalence of Hepatitis B Surface Antigen among patients attending Aminu Kano

Nwokedi, Emmanuel; Odimayo, M. S.; Emokpae, AM; Yahaya, Isah Adagiri; Sadiq, Mehjabeen; Okwori, EE

doi:10.4314/njm.v19i4.61968

Cited by 12 publications

(11 citation statements)

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“…Here the difference is close to be significant (p=0.12), so this calls for particular attention from health care providers when treating this patient population. We see that HBV/HIV co-infection affects females and males at the same rate, which is in accordance with a study of 6395 patients in Northern Nigeria where Nwokedi et al saw a similar infection rate between the two genders in the overall population 21 . This similar gender distribution is seen in all four categories, and demonstrates a relatively consistent studied population.…”

Section: Discussionsupporting

confidence: 79%

Seroprevalence of hepatitis B and C infection among the HIV-positive population in Abuja, Nigeria

Tremeau‐Bravard¹,

Ogbukagu²,

Ticao³

et al. 2013

Af Hlth Sci

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Background: In Nigeria, it is estimated that 3.6% of the population were living with Human immunodeficiency virus in 2009, and the country had the world's second highest number of HIV/AIDS related deaths after South Africa. Viral hepatitis is also a major public health concern as hepatitis B virus (HBV) afflicts an estimated 350 million people, and hepatitis C virus (HCV) affects 150 million people worldwide. Objectives: We conducted a retrospective study of HBV and HCV seroprevalence among Nigerian population coming to our clinic in Abuja and receiving HIV/AIDS treatment. Methods: In this cohort study, we collected medical data from 443 HIV-positive patients between September 2010 and May 2011. Standard enzyme immunoassays were used to determine the serological prevalence of hepatitis B (HBsAg) and C (anti-HCV antibody) among HIV-positive individuals. Results: Among the HIV/AIDS positive individuals, we found that 35 patients were infected with hepatitis B virus (7.9%), 10 with hepatitis C virus (2.3%) and 3 with both hepatitis B and C viruses (0.7%). The overall hepatitis-HIV prevalence is 10.8%. The majority of the population infected was under 39 years of age (55%) and the same proportion of males and females was observed in all the studied categories (HIV, HIV + hepatitis B and/or C). Remarkably, an overall lower CD4 count was seen in the co-infected population (205 cells/μl versus 243 cells/μl), with the lowest seen for the triply infected individuals (97 cells/μl). Conclusions: Our findings underscore the importance of screening for hepatitis B and hepatitis C viruses in the HIVinfected population in developing countries, and particularly in sub-Saharan Africa, where the epidemics are still growing.

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Section: Discussionsupporting

confidence: 79%

Seroprevalence of hepatitis B and C infection among the HIV-positive population in Abuja, Nigeria

Tremeau‐Bravard¹,

Ogbukagu²,

Ticao³

et al. 2013

Af Hlth Sci

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“…This study presents prevalence of HBsAg at 6.5% which differs from the results obtained from other studies within the same state and from other geopolitical zones of Nigeria. Prevalence rates obtained in the last one decade showed a fluctuating trend, 14.6% in 2004, and 10.1% in 2005 and in 2006 it was 10.7% (Nwokedi, 2010). Recent report on the prevalence of Hepatitis B infection on adolescent in Kano puts the rate at 12.5% (Yunusa, 2014).…”

Section: Discussionmentioning

confidence: 99%

Malaria and Hepatitis B co-infection in patients with febrile illnesses attending general outpatient unit of the Murtala Muhammed Specialist Hospital, Kano, Northwest Nigeria

Dabo¹,

Sharif²,

Muhammed³

et al. 2015

Bayero J. Pure App. Sci.

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Malaria and Hepatitis B Virus (HBV) infections are co-endemic throughout much of the tropical and sub-Saharan Africa and both present major threat to public health. A study on the prevalence of HBV and Malaria co-infection was carried out on 200 patients presenting with fever at the General Outpatient Department (GOPD) of the Murtala Muhammed Specialist Hospital (MMSH), Kano using Gold Standard microscopy and rapid diagnostic test (RDT). The effect of mono and co-infection on hematological parameters was also investigated. Fifty one (25.5%) out of the 200 patients studied were Malaria positive. Females had higher prevalence rate(18%) of Malaria infection than males with 7.5%. Age group 15-24 had the highest Malaria prevalence (11%) followed by age group 25-34 with 6.5%. Higher mean parasite density (1,200/µl) was recorded among subjects with monoinfection of Malaria than mean parasite density (518/µl) obtained among the co-infected. Mean parasite density was higher in female than male subjects. Thirteen (6.5%) subjects were HBV positive. Males had higher rate of infection with 4.5% prevalence than females with 2.0%. Nine individuals representing 4.5% of the total population had co-infection with higher prevalence (3%) among the males. Age groups 25-34 were observed to have high co-infection rate of 1.5% and the least prevalence was observed among the age group 15-24 with 0.5% prevalence for both males and females. Hematological evaluation carried out on all the categories of subjects shows significant difference in mean values of PCV (P=0.041), Hb (P=0.018) between the co-infection group and those with malaria infection and control groups. However, no significant difference (P>0.05) was observed in the values of WBC, PLT and Red cell indices among the co-infected and other test group. It was concluded that co-infection with the two ailments had no profound effect on hematologic parameters.

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“…A yearly trend of HBsAg seropositivity in North-western Nigeria of 14.6% in 2004, 10.1% in 2005, 10.7% in 2006 and 11.4% in 2010 have been reported in blood donors [19]. A seroprevalence of 2.4% in the North-eastern, 2.19%, 51.9% and 4.3% in the South-western and South-southern Nigeria have been reported [20-23].…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of hepatitis B surface antigenemia and its effects on hematological parameters in pregnant women in Osogbo, Nigeria

Kolawole

Wahab

Adekanle

et al. 2012

Virol J

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BackgroundThe transmission of the hepatitis B virus (HBV) is parenteral, sexual and perinatal. Prevention of vertical transmission of HBV is extremely important because HBV infection in early life usually results in a chronic carrier State.MethodsA descriptive seroepidemiological study of hepatitis B virus and its effects on hematological parameters was investigated in pregnant women attending antenatal clinic of LAUTECH Teaching Hospital, Osogbo, Nigeria. 200 venous samples were subjected to full blood count and its sera were subjected to enzyme–linked immunosorbent assay for the detection of surface antigen of hepatitis B virus.ResultsPrevalence rate of 16.5% was obtained for hepatitis B surface antigen in pregnant women. The highest HBsAg prevalence rate recorded was 23.3% for pregnant women between aged 30–34 years while the lowest recorded was zero percent for those aged greater than 40 years. RBC, WBC, neutrophil, hemoglobin lymphocyte and platelet counts have no significant effects on HBsAg positivity of pregnant women (p = 0.801). There was no significant difference in HBsAg positivity in relation to maternal age, gravidity, gestational age, family type, level of education and occupation (p = 0.073). Among the potential risk factors, there was significant difference in HBsAg positivity in the pregnant women in relation to their history of HBV vaccination (p = 0.039).ConclusionsWe advocate universal free screening of pregnant women as the endemicity of HBV infections is thus being propagated.

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Seroprevalence of Hepatitis B Surface Antigen among patients attending Aminu Kano

Cited by 12 publications

References 0 publications

Seroprevalence of hepatitis B and C infection among the HIV-positive population in Abuja, Nigeria

Seroprevalence of hepatitis B and C infection among the HIV-positive population in Abuja, Nigeria

Malaria and Hepatitis B co-infection in patients with febrile illnesses attending general outpatient unit of the Murtala Muhammed Specialist Hospital, Kano, Northwest Nigeria

Seroprevalence of hepatitis B surface antigenemia and its effects on hematological parameters in pregnant women in Osogbo, Nigeria

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