Seroprevalence of hepatitis B Surface antigen among apparently healthy primary school pupils in Batagarawa Local Government area of Katsina State, Nigeria

Habibu, B; Belonwu, RO; Ibrahim, Mbarawa Marat Kofia

doi:10.4314/njp.v44i3.2

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…Considering gender, this study showed that more males subjects 34(11.2%) were seropositive for HBV infection; this findings is similar to the report of Ashir et al [10] ; Habib et al [20]; Sabir et al [21]. Nwoediuko (24) in his report also recorded a significantly higher (79.2%) rate of infection among male subjects compared to females (20.8%).…”

Section: Discussionsupporting

confidence: 88%

Study on Hepatitis B Virus Infection and Risk Factors among Children in a Community, North Central Nigeria

Ndako

Ojo

Fajobi

et al. 2021

JAMB

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Background: Hepatitis B Virus (HBV) is a worldwide health issue and a source of major concern around the globe. Infections caused by hepatitis B virus pose a major challenge to public health. This study evaluates the prevalence and transmission rate of Hepatitis B Virus infection among children of primary school age at our study location. Method: Three hundred and three (303) volunteer subjects were screened.Structured questionnaire were administered to consenting participants to determine demographic and other risk factors for HBV infection.Samples obtained were analysed using a Laboratory-based immunoassay-HBsAg rapid diagnostic test (RDTs) in lateral flow assays formats. Sera samples obtained were stored at -20oc prior use. Results: Overall result showed that 46 (15.2%) were sero-positive for HBV infection. Considering age factor, Children aged 10 – 12 years showed a higher prevalence of 16(5.3%) [P-value 0.736; (P >0.05)]. Based on gender of subjects screened, a prevalence of 34(11.2%) was recorded among the males subjects compared to females with 12(4.0%) positivity, [(P < 0.05)]. Risk factors on family history recorded 13(4.3%) positivity, considering place of circumcision as risk factors among male subjects; result showed that subjects circumcised using traditional methods recorded 17 (11.7%) positivity. [P-value 0.856 (P>0.05)].Respondents with history of cuts recorded a prevalence of 29(9.6%) positivity; [P-Value 0.362 (P>0.05)] considering enzyme assay of positive subjects, 13 (4.3%) subjects recorded an elevated Alanine transaminases. Conclusion: The transmission rate of HBV infection among the family members was found to be high in this study. This upsurge calls for an urgent vaccination of the population by relevant healthcare providers.

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Section: Discussionsupporting

confidence: 88%

Study on Hepatitis B Virus Infection and Risk Factors among Children in a Community, North Central Nigeria

Ndako

Ojo

Fajobi

et al. 2021

JAMB

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Hepatitis B virus infection in Nigeria: a systematic review and meta-analysis of data published between 2010 and 2019

et al. 2021

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Background Hepatitis B virus (HBV) is an infectious disease of global significance, causing a significant health burden in Africa due to complications associated with infection, such as cirrhosis and liver cancer. In Nigeria, which is considered a high prevalence country, estimates of HBV cases are inconsistent, and therefore additional clarity is required to manage HBV-associated public health challenges. Methods A systematic review of the literature (via PubMed, Advanced Google Scholar, African Index Medicus) was conducted to retrieve primary studies published between 1 January 2010 and 31 December 2019, with a random-effects model based on proportions used to estimate the population-based prevalence of HBV in the Nigerian population. Results The final analyses included 47 studies with 21,702 participants that revealed a pooled prevalence of 9.5%. A prevalence estimate above 8% in a population is classified as high. Sub-group analyses revealed the highest HBV prevalence in rural settings (10.7%). The North West region had the highest prevalence (12.1%) among Nigeria’s six geopolitical zones/regions. The estimate of total variation between studies indicated substantial heterogeneity. These variations could be explained by setting and geographical region. The statistical test for Egger’s regression showed no evidence of publication bias (p = 0.879). Conclusions We present an up-to-date review on the prevalence of HBV in Nigeria, which will provide critical data to optimise and assess the impact of current prevention and control strategies, including disease surveillance and diagnoses, vaccination policies and management for those infected.

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Prevalence of hepatitis B viral infection at paediatric gastroenterology clinic of ABUTH, Zaria

Hafsat

Sakinatu

Aliyu

et al. 2018

Niger J Basic Clin Sci

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Seroprevalence of hepatitis B Surface antigen among apparently healthy primary school pupils in Batagarawa Local Government area of Katsina State, Nigeria

Cited by 3 publications

References 8 publications

Study on Hepatitis B Virus Infection and Risk Factors among Children in a Community, North Central Nigeria

Study on Hepatitis B Virus Infection and Risk Factors among Children in a Community, North Central Nigeria

Hepatitis B virus infection in Nigeria: a systematic review and meta-analysis of data published between 2010 and 2019

Prevalence of hepatitis B viral infection at paediatric gastroenterology clinic of ABUTH, Zaria

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