Seroprevalence of Five Zoonotic Pathogens in Wild Ruminants in Xinjiang, Northwest China

Wu, Jian-Yong; Li, Jianjun; Wang, Dengfeng; Wei, Yu-Rong; Meng, Xiaoxiao; Tuerxun, Gunuer; Bolati, Hongduzi; Liu, Kangkang; Muhan, M; Shahan, Ayiqiaolifan; Dilixiati, Dilireba; XueYun, Yang

doi:10.1089/vbz.2020.2630

Cited by 3 publications

(3 citation statements)

References 40 publications

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“…A study which conducted serum detection for 258 wild ruminants in Xinjiang found that the Brucella spp. serum positive rate was 2.3% (95 con dence interval 0.5-4.2%) [41] , which to some extent supports the results of this study. The results of this study provide insights and basic data for the prevention and control of brucellosis in Xinjiang, and even in China.…”

Section: Discussionsupporting

confidence: 90%

Analysis of the Brucella melitensis epidemic in Xinjiang: Genotyping, polymorphism, antibiotic resistance and tracing

Yang

Liang

Li³

et al. 2023

Preprint

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Brucella spp. are facultative intracellular pathogens that cause the zoonosis- brucellosis worldwide. There has been a trend of the re-emergence of brucellosis worldwide in recent years. Xinjiang is located in northwestern China and in the hinterland of the Eurasian continent. The epidemic situation of brucellosis is serious in Xinjiang. To analyze the epidemic situation of Brucella spp. in Xinjiang among humans and animals, this study used 16S rRNA amplification to identify 144 isolates of Brucella and their biovars. MLVA, drug resistance testing, and wgSNP detection were also performed. At the same time, analysis based on the published data of Brucella isolates worldwide was conducted. The results showed that the dominant species was B. melitensis biovar 3 and the correlation among isolates was high, whether in humans or animals. Since 2010, the polymorphism of isolates in Xinjiang has been increasing each year. No reported amikacin/kanamycin-resistant strains were found, but 6 rifampicin-intermediate isolates were found without rpoB gene variation. The NJ tree of the wgSNP results indicated that there were three main complexes of the B. melitensis epidemic in Xinjiang. In conclusion, the dominant Brucella species has greatest genetic variation in Xinjiang than other location in China, and the rifampicin-resistant trend has been existed in Xinjiang. This study analyzes the prevalence, genotyping, diversity, drug resistance, and tracing of B. melitensis in Xinjiang. The results provide basic data for the prevention and control of brucellosis in Xinjiang and China.

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Section: Discussionsupporting

confidence: 90%

Analysis of the Brucella melitensis epidemic in Xinjiang: Genotyping, polymorphism, antibiotic resistance and tracing

Yang

Liang

Li³

et al. 2023

Preprint

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“…In another study carried out in Africa, an increased number of infections in farmed animals was demonstrated in areas where contact with the local wild fauna and people occurs, due to the lack of physical barriers [ 183 ]. The same situation seems also to be present in northeastern China in the Xinjiang region, where goitered gazelles ( Gazella subgutturosa ) were found positive for C. abortus , and thus are considered a carrier in this region [ 184 ].…”

Section: Environmental Contaminationmentioning

confidence: 99%

Recent advances and public health implications for environmental exposure to Chlamydia abortus: from enzootic to zoonotic disease

Turin

Surini

Wheelhouse

et al. 2022

Vet Res

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Environmental transmission of Chlamydia abortus as a result of enzootic disease or disease outbreaks and the threats posed by this pathogen has been previously reported, however a state-of-the-science review of these reports and the identification of future research priorities in this area is still lacking. This study provides an overview of the current knowledge of host–pathogen–environment interactions, addressing public health risks and identifying critical questions and research gaps. We performed a systematic PubMed and Web of Science search for publications related to Chlamydia abortus in the past four decades, and we reviewed and combined the evidence critically discussing and commenting the results. A total of 182 studies, 5 chapters of specific books and the “OIE terrestrial manual” were included in this review. There were substantial variations between the studies in topic addressed and experimental design. Overall, the literature largely supports the crucial role played by environmental exposure on the acquisition of zoonotic disease caused by Chlamydia abortus. We also identify the paucity of information related to interspecies transmission and pathogen adaptation in relation to environmental dissemination and zoonotic risk. This analysis further highlights the need for additional research given that environmental transmission represents a serious risk not only to susceptible patients (pregnant women and immunocompromised individuals), but also for other species including wildlife.

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“…Considering that all investigated bacteria as well as T. gondii are zoonotic agents, these investigations are also useful from a One Health perspective. In fact, previous studies showed that wild ruminants can provide a bridge for the transmission of pathogens from wildlife into domestic livestock and humans [ 58 ]. Wild ruminants can contaminate the environments shared by persons for recreational or work activities as well as can directly be sources of infections for hunters during the carcasses’ manipulation.…”

Section: Discussionmentioning

confidence: 99%

Retrospective Molecular Survey on Bacterial and Protozoan Abortive Agents in Roe Deer (Capreolus capreolus) from Central Italy

Ebani

Trebino

Guardone

et al. 2022

Animals

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Bacterial and protozoan agents can determine abortion and other reproductive disorders in domestic ruminants, but data regarding their occurrence in wild ruminants are scanty worldwide, including in Italy. The aim of this retrospective study was to verify the occurrence of the main bacterial and protozoan abortive agents in 72 spleen samples previously collected from roe deer (Capreolus capreolus) living in mountain areas of Central Italy. All samples were collected and submitted to DNA extraction for other investigations. Molecular analyses were carried out on the DNA samples to detect Brucella spp., Chlamydia abortus, Coxiella burnetii, Salmonella enterica, Listeria monocytogenes, Neospora caninum, and Toxoplasma gondii. Three (4.16%) roe deer resulted PCR positive for C. burnetii and one (1.38%) for T. gondii. These findings suggest that roe deer living in the investigated areas do not act as important reservoirs of the searched agents. However, the tested animals lived in a closed area without contact with domestic animals that are usually involved in the epidemiology of the investigated pathogens. Monitoring of wild ruminants is pivotal to verify changes in the epidemiological scenario from a One Health perspective, too.

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Seroprevalence of Five Zoonotic Pathogens in Wild Ruminants in Xinjiang, Northwest China

Cited by 3 publications

References 40 publications

Analysis of the Brucella melitensis epidemic in Xinjiang: Genotyping, polymorphism, antibiotic resistance and tracing

Analysis of the Brucella melitensis epidemic in Xinjiang: Genotyping, polymorphism, antibiotic resistance and tracing

Recent advances and public health implications for environmental exposure to Chlamydia abortus: from enzootic to zoonotic disease

Retrospective Molecular Survey on Bacterial and Protozoan Abortive Agents in Roe Deer (Capreolus capreolus) from Central Italy

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