Seroprevalence of Cytomegalovirus among Voluntary Blood Donors

Chaudhari, CN; Bindra,

doi:10.1016/s0377-1237(09)80016-6

Cited by 14 publications

(10 citation statements)

References 12 publications

(24 reference statements)

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“…The low CMV IgM positivity reported in our study is matching the low rates reported in the studies conducted in Jordan [11], Syria [12], Iran [5], and India [10]. Chaudhari and Bindra [10] conducted a prospective study in which 431 voluntary blood donors were screened for CMV IgG and IgM and found that 379 (87.9 %) subjects were seropositive for CMV IgG while seven (1.6%) were CMV IgM positive.…”

Section: Discussionsupporting

confidence: 87%

“…Chaudhari and Bindra [10] conducted a prospective study in which 431 voluntary blood donors were screened for CMV IgG and IgM and found that 379 (87.9 %) subjects were seropositive for CMV IgG while seven (1.6%) were CMV IgM positive. Recently, Bagheri et al [5] collected 240 serum samples from Iranian pregnant women and measured the CMV IgG and IgM markers using ELIZA method and found that the CMV seropositivity rate was 72.1%.…”

Section: Discussionmentioning

confidence: 99%

“…Based on the fact that CMV can be transmitted via transfusion of blood or blood components [10], CMV-seronegative recipients are at a risk of primary infection with this virus after receiving blood or blood products from CMV-seropositive donors [13,14]. On the other hand, CMV-seropositive recipients are also at risk of reinfection by a new strain of this virus when they receive blood products from CMV-seropositive donors [14].…”

Section: Discussionmentioning

confidence: 99%

“…Consequently, CMV establishes a latent lifetime infection that may be reactivated by changed immune status [9,10].…”

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of cytomegalovirus among healthy students at Diyala University, Diyala, Iraq

Khudir¹,

Molan²

2014

IOSRJPBS

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Consequently, CMV establishes a latent lifetime infection that may be reactivated by changed immune status [9,10].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Seroprevalence of cytomegalovirus among healthy students at Diyala University, Diyala, Iraq

Khudir¹,

Molan²

2014

IOSRJPBS

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“…[38] In India, the seroprevalence of HCMV is reported to be very high among normal population and renal transplant patients. [39–41] In our earlier report, we reported the rate of positivity of HCMV to be very high among the transplant patients. [27] Therefore a pp65 antigenemia count of 10 reported based on the Western literature[42–46] may not reflect the true situation of replication of HCMV in PBLs in Indian patients.…”

Section: Discussionmentioning

confidence: 98%

Determination of human cytomegalovirus pp65 antigenemia among renal transplant patients

Moses¹,

Malathi²,

Singha³

et al. 2012

Indian J Nephrol

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Human cytomegalovirus (HCMV) is an important cause of morbidity and mortality in immunosuppressed transplant recipients. Isolation of HCMV from peripheral blood leukocytes (PBLs) is considered a reliable marker of disseminated HCMV infection. HCMV pp65 antigenemia is widely used for monitoring CMV infection and guiding preemptive therapy. The aim of this study was to compare pp65 antigenemia with culture technique for detection of HCMV in PBLs among kidney transplant patients and also to determine the threshold value of significant pp65 antigenemiat. Fifty-one peripheral blood samples from post-renal transplant patients collected during August 2009 to March 2011 were processed for pp65 antigenemia assay. These were also tested for isolation of the virus by inoculation into human corneal fibroblast cells. The results of pp65 antigenemia and culture were compared to determine the clinical significance of pp65 antigenemia. HCMV was isolated in 21 cases. On comparing the pp65 antigenemia results with that of the viral isolation, a mean of 23 cells was determined to yield a positive isolation of HCMV. The values of pp65 antigenemia and isolation results were correlated (paired t-test, P = 0.0029). A pp65 count of 23 and above was considered significant in our clinical settings since we found that these clinical specimens yield positive culture result.

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Multi-institutional, retrospective review of blood transfusion practices and outcomes in a large cohort of thalassemia patients in South India

Agarwal

Sedai

Ankita

et al. 2017

Pediatric Hematology Oncology Journal

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Seroprevalence of Cytomegalovirus among Voluntary Blood Donors

Cited by 14 publications

References 12 publications

Seroprevalence of cytomegalovirus among healthy students at Diyala University, Diyala, Iraq

Seroprevalence of cytomegalovirus among healthy students at Diyala University, Diyala, Iraq

Determination of human cytomegalovirus pp65 antigenemia among renal transplant patients

Multi-institutional, retrospective review of blood transfusion practices and outcomes in a large cohort of thalassemia patients in South India

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