Abstract:Brucellosis is one of the most notorious and widespread zoonosis caused by Brucella abortus. It is of serious economic implications to the cattle industry and thus enormous financial losses to most countries. This study focused on it serological prevalence at the Nkwen main abattoir of Bamenda (Northwest region, Cameroon) from June to September 2013. Blood samples were collected from 198 cattle and the sera were screened using the competitive enzyme linked immuno sorbent assay (C-ELISA). Results showed a serop… Show more
“…The better management in the cross herds, intensive feeding that minimize contacts between animals and may be responsible for this difference. This finding is consistent with some previous studies in Ethiopia ( Alehegn et al., 2017 ; Asfaw et al., 2016 ; Jergefa et al., 2009 ) and elsewhere ( Kong, Nsongka, Itoe, Hako, and Leinyuy, 2016 ; Kushwaha et al., 2016 ; Matope et al., 2010 ) stated that seropositive of Brucella antibody was statistically significantly associated with breed in cattle. However, Kebede et al.…”
Bovine brucellosis is a serious zoonotic infectious disease with widespread occurrence in developing countries like Ethiopia. A cross-sectional study was conducted from November 2017 to November 2018 to investigate the prevalence and associated risk factors of brucellosis in breeding female cattle under the traditional production system of the Jimma zone in Ethiopia. Blood samples were collected from a total of 423 breeding female cattle to test the presence of
Brucella
antibody. The presence of antibody against
Brucella
spp. was serially tested first by the Rose Bengal Plate test, then positive sera were confirmed using the complement fixation test. Potential risk factors for
Brucella
seropositivity were analyzed using multivariable logistic regression analysis. An overall 11.6% (95%CI: 6.25
–
16.94) and 4.3% (95%CI: 2.15–5.89) seroprevalence of brucellosis was recorded at herd and animal level, respectively in study areas. We identified age (OR=9.6, 95% CI: 2.08–44.07), breed (OR=4.5, 95%CI: 1.54–12.99), herd size (OR=10.4, 95%CI: 1.27–85.04) and species composition (OR=4.4, 95%CI: 1.31–14.89) as risk factors for
Brucella
infection. Herd level analysis of risk factor shows that herds kept with sheep and/goats was at higher risk (OR=3.7, 95% CI: 1.25–11.17) of acquired
Brucella
infection. This result showed that brucellosis was a widely spread disease in the study areas. Thus, important to carry out appropriate control methods and creating awareness on public zoonotic transmissions of brucellosis are recommended. Moreover, further investigation should be carried out to isolate and characterized brucellosis as a cause of reproduction problems in the study areas.
“…The better management in the cross herds, intensive feeding that minimize contacts between animals and may be responsible for this difference. This finding is consistent with some previous studies in Ethiopia ( Alehegn et al., 2017 ; Asfaw et al., 2016 ; Jergefa et al., 2009 ) and elsewhere ( Kong, Nsongka, Itoe, Hako, and Leinyuy, 2016 ; Kushwaha et al., 2016 ; Matope et al., 2010 ) stated that seropositive of Brucella antibody was statistically significantly associated with breed in cattle. However, Kebede et al.…”
Bovine brucellosis is a serious zoonotic infectious disease with widespread occurrence in developing countries like Ethiopia. A cross-sectional study was conducted from November 2017 to November 2018 to investigate the prevalence and associated risk factors of brucellosis in breeding female cattle under the traditional production system of the Jimma zone in Ethiopia. Blood samples were collected from a total of 423 breeding female cattle to test the presence of
Brucella
antibody. The presence of antibody against
Brucella
spp. was serially tested first by the Rose Bengal Plate test, then positive sera were confirmed using the complement fixation test. Potential risk factors for
Brucella
seropositivity were analyzed using multivariable logistic regression analysis. An overall 11.6% (95%CI: 6.25
–
16.94) and 4.3% (95%CI: 2.15–5.89) seroprevalence of brucellosis was recorded at herd and animal level, respectively in study areas. We identified age (OR=9.6, 95% CI: 2.08–44.07), breed (OR=4.5, 95%CI: 1.54–12.99), herd size (OR=10.4, 95%CI: 1.27–85.04) and species composition (OR=4.4, 95%CI: 1.31–14.89) as risk factors for
Brucella
infection. Herd level analysis of risk factor shows that herds kept with sheep and/goats was at higher risk (OR=3.7, 95% CI: 1.25–11.17) of acquired
Brucella
infection. This result showed that brucellosis was a widely spread disease in the study areas. Thus, important to carry out appropriate control methods and creating awareness on public zoonotic transmissions of brucellosis are recommended. Moreover, further investigation should be carried out to isolate and characterized brucellosis as a cause of reproduction problems in the study areas.
“…Represented in Table 1 , five of the studies used the Rose Bengal Test (RBT) in combination with the indirect enzyme-linked immunosorbent assay (iELISA) [ 18 , 24 – 27 ], and one used RBT in combination with the complement fixation test (CFT) for confirmation [ 17 ]. In contrast, two studies simply employed the RBT [ 16 , 23 ], and the remaining four relied solely on the competitive ELISA (C-ELISA) [ 19 – 22 ]. Each of these tests embodies a distinctive method of identification and should be interpreted carefully as the positive vs. negative values between various tests differ.…”
Brucellosis is a zoonotic disease known to be endemic to parts of western and sub-Saharan Africa. However, the epidemiology for humans and animals remains largely unknown in many of these countries with Cameroon being a typical example. Despite common knowledge that brucellosis affects livestock, the actual number of infected animals remains unknown. Through a scoping review, the current known status of the disease is described. The aim is to ascertain relevant and publicly accessible research and knowledge of human and animal brucellosis in the country, and to provide an overview of the factors associated with its known persistence. Seroprevalence has been estimated and published in 12 separate instances (1 human; 9 cattle; 1 human and cattle; and 1 that includes cattle, pigs, and small ruminants), between 1982 and 2020, in 9 of the country's 10 geopolitical regions. In 1983, Brucella abortus and B. melitensis were isolated in cattle, but no further bacterial isolation has been published since. The seroprevalence from 196 total humans has ranged between 5.6% and 28.1%, and between 3.0% and 30.8% for 14,044 total cattle. As there is no ongoing surveillance program, it is not currently possible to identify the specific Brucella spp. that are endemic to the country and its regions. There are sufficient agricultural systems of cattle, pigs, goats, and sheep to sustain the presence of multiple Brucella spp. Surveillance information is the cornerstone of epidemiologic decision making, and is needed to direct policy makers, public health authorities, and veterinary services to appropriate actions. A combination of serological and molecular based diagnostics for surveillance is necessary to identify, quantify, and direct the appropriate public health interventions. Cameroon has an opportunity to build public and animal health infrastructure, leading the way for central Africa in the management and future eradication of brucellosis.
“…Previous estimates of Brucella spp. seroprevalence in pastoral cattle in Cameroon (estimated individual animal prevalence in the NWR (4.4%) (Kong et al, 2016), Adamawa (3.1%-11.5%) (Awah-Ndukum, Scolamacchia et al, 2010) and North Regions (6.1%) (Awah-Ndukum, )…”
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.