Serological surveillance of H5 and H9 avian influenza A viral infections among pigs in southern China

Yuan, Zhaoxia; Zhu, Wanjun; Chen, Ye; Zhou, Pei; Cao, Zanxia; Xie, Jiexiong; Zhang, Changhui; Ke, Changwen; Qi, Wenbao; Su, Shuo; Zhang, Guihong

doi:10.1016/j.micpath.2013.08.001

Cited by 11 publications

(11 citation statements)

References 18 publications

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“…Three studies showed 0% prevalence for H5N1 (n = 2) and H5 and H9 (n = 1) in farms in China and South Korea. In one of the studies testing for H5N1, H9 was also tested and showed a pig-level seroprevalence of 4.6% (181/3960), however the herd-level seroprevalence was not given for this subtype [45]. Two studies carried out in China and Egypt showed a herd-level seroprevalence of 36.4% (4/11).…”

Section: Resultsmentioning

confidence: 99%

Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis

et al. 2017

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BackgroundThe emergence of the 2009 influenza pandemic virus with a swine origin stressed the importance of improving influenza surveillance in swine populations. The objectives of this systematic review and meta-analysis were to describe epidemiological features of swine influenza (SI) across the world and identify factors impacting swine influenza virus surveillance.MethodsThe systematic review followed the PRISMA guidelines. Articles published after 1990 containing data on SI on pig and herd-level seroprevalence, isolation and detection rates, and risk factors were included. Meta-regression analyses using seroprevalence and virological rates were performed.ResultsA total of 217 articles were included. Low avian influenza (AI) seroprevalence (means pig = 4.1%; herd = 15%) was found, showing that AIV do not readily establish themselves in swine while SIV seroprevalence was usually high across continents (influenza A means pig = 32.6–87.8%; herd = 29.3–100%). Higher pig density and number of pigs per farm were shown by the meta-regression analyses and/or the risk factor articles to be associated with higher SI seroprevalence. Lower seroprevalence levels were observed for countries with low-to-medium GDP. These results suggest that larger industrial farms could be more at risk of SIV circulation. Sampling swine with influenza-like illness (ILI) was positively associated with higher isolation rates; most studies in Europe, Latin and North America were targeting swine with ILI.ConclusionsTo improve understanding of SI epidemiology, standardization of the design and reporting of SI epidemiological studies is desirable. Performance of SI surveillance systems in low-to-medium GDP countries should be evaluated to rule out technical issues linked to lower observed SIV prevalence. Targeting certain swine age groups, farming systems and swine with ILI may improve the surveillance cost-effectiveness. However, focusing on pigs with ILI may bias virus detection against strains less virulent for swine but which may be important as pandemic threats.

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Section: Resultsmentioning

confidence: 99%

Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis

et al. 2017

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“…Outbreaks of HPAI have led to human infections, some of which resulted in deaths (Chan 2002;Yuan et al 2013). Influenza A viruses can be subdivided into several subtypes based on the antigenic nature of the surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA) (Hinshaw et al 1982).…”

Section: Introductionmentioning

confidence: 99%

Multiplexed detection of influenza A virus subtype H5 and H9 via quantum dot-based immunoassay

Yuan

Zhou

et al. 2016

Biosensors and Bioelectronics

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A quantum dot-based lateral flow immunoassay system (QD-LFIAS) was developed to simultaneously detect both influenza A virus subtypes H5 and H9. Water-soluble carboxyl-functionalized quantum dots (QDs) were used as fluorescent tags. The QDs were conjugated to specific influenza A virus subtype H5 and H9 antibodies via an amide bond. When influenza A virus subtype H5 or H9 was added to the QD-LFIAS, the QD-labeled antibodies specifically bound to the H5 or H9 subtype viruses and were then captured by the coating antibodies at test line 1 or 2 to form a sandwich complex. This complex produced a bright fluorescent band in response to 365 nm ultraviolet excitation. The intensity of fluorescence can be detected using an inexpensive, low-maintenance instrument, and the virus concentration directly correlates with the fluorescence intensity. The detection limit of the QD-LFIAS for influenza A virus subtype H5 was 0.016 HAU, and the detection limit of the QD-LFIAS for influenza A virus subtype H9 was 0.25 HAU. The specificity and reproducibility were good. The simple analysis step and objective results that can be obtained within 15 min indicate that this QD-LFIAS is a highly efficient test that can be used to monitor and prevent both Influenza A virus subtypes H5 and H9.

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“…[5,37,43,45,46,61,74,88,137,157,171,176,188,191,199,207,215,[219][220][221]241,243,248,250,263,289,290,301,306,307,326,334] IAV, IDV, H1N1, H1N2, H3N2, A(H1N1)pdm09 [45,192,227,282,285,287,302,322] 8. Blood/ serum IDEXX Ab test, ELISA, HI assay, NI assay, VN assay, MN assay, western blot, virus isolation (MDCK cells) H1N1, H1N2, H3N2, A(H1N1)pdm09, H5N1, H5N2, H5N3, H9N2, H7N9, H3N1, H4N8, H6N6, H6N2, H7N2, IBV, ICV, IDV [37,38,46,52,59,70,79,96,…”

Section: Discussionmentioning

confidence: 99%

“…The third report of avian-origin H9N2 virus in Chinese swine appeared when 144 apparently healthy swine across four provinces viz., Yunnan, Guangdong, Fujian and Zhejiang were found H9N2 positive over a four-year period during March 2008-March 2012. The frequent interactions of birds to the swine at the study sites was reported which was suspected to be the most likely source of infection [79]. Further, a novel strain of avian-origin H4N1 virus was isolated from a Chinese swine in 2009 [80].…”

Section: Chinamentioning

confidence: 97%

A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide

Chauhan

Gordon

2020

Pathogens

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The global anxiety and a significant threat to public health due to the current COVID-19 pandemic reiterate the need for active surveillance for the zoonotic virus diseases of pandemic potential. Influenza virus due to its wide host range and zoonotic potential poses such a significant threat to public health. Swine serve as a "mixing vessel" for influenza virus reassortment and evolution which as a result may facilitate the emergence of new strains or subtypes of zoonotic potential. In this context, the currently available scientific data hold a high significance to unravel influenza virus epidemiology and evolution. With this objective, the current systematic review summarizes the original research articles and case reports of all the four types of influenza viruses reported in swine populations worldwide. A total of 281 articles were found eligible through screening of PubMed and Google Scholar databases and hence were included in this systematic review. The highest number of research articles (n = 107) were reported from Asia, followed by Americas (n = 97), Europe (n = 55), Africa (n = 18),

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Serological surveillance of H5 and H9 avian influenza A viral infections among pigs in southern China

Cited by 11 publications

References 18 publications

Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis

Epidemiological features of influenza circulation in swine populations: A systematic review and meta-analysis

Multiplexed detection of influenza A virus subtype H5 and H9 via quantum dot-based immunoassay

A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide

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