Serological, clinical, and epidemiological profile of human brucellosis in rural India

Mangalgi, Smita S; Sajjan, Annapurna G; Mohite, Shivajirao T; Kakade, Satish V.

doi:10.4103/0970-0218.158847

Cited by 24 publications

(15 citation statements)

References 17 publications

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“…14,16 While in contrast, no significant sex difference was observed in other studies. 13,24 Furthermore, a female predominance was reported in a small study from Saudi Arabia. 17 These variations are most likely related to the differences in occupation, practice, and habits of individuals among the various study populations.…”

Section: Discussionmentioning

confidence: 97%

Epidemiological characteristics of human brucellosis in Al-Qassim region, Saudi Arabia, between 2010 and 2014

Alsoghair

2016

Int J Community Med Public Health

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Background: Brucellosis, a zoonotic infection having an important public health issue in endemic countries; Saudi Arabia is one of these countries. The incidence of brucellosis in AlQassim region is much higher than the national one. Evaluation of the epidemiological situation of brucellosis is the first step in prevention and control. The objective was to describe the epidemiological characteristics of brucellosis in Al-Qassim region during the period between 2010 and 2014. Methods: All epidemiological surveillance forms from 2010 to 2014 were analyzed for epidemiological characteristics. Results: There were 4283 notified cases of human brucellosis in AL-Qassim region between 2010 and 2014, the annual incidence decreased from 84.5 to 48.7 per 100,000 populations. The highest number of cases was reported from Uyoon Al-Jawa followed by Buraidah. The number of cases was highest from March to June. and lowest was in November; the male to female ratio was 3:1. Saudis represents 51.1% of cases. The mean age of the cases was 34±15 years; the most common age group was middle age. Shepherds and farmers represent 46.5% of cases. The most common presenting symptoms were fever (79.7%), joint pain (72.7%), and muscle pain (70.9%). The most common antibiotics used as treatment were doxycycline (80.9%) and streptomycin (63.2%). A history of animal contact was the most common risk factor (80.7%), followed by consumption of raw milk (55.6%). Conclusions:There was a marked decrease in the incidence of brucellosis from 2010 to 2014 in the Al-Qassim region. However, continued efforts are needed to eliminate the disease.

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Section: Discussionmentioning

confidence: 97%

Epidemiological characteristics of human brucellosis in Al-Qassim region, Saudi Arabia, between 2010 and 2014

Alsoghair

2016

Int J Community Med Public Health

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“…Goel et al, Mangalgi et al and Yohannes et al noted similar findings. [3][4][5] In the present study, 6 out of 111 patients showed serological evidence of Brucella. 4 out of 6 were males and 2 were females.…”

Section: Discussionmentioning

confidence: 66%

Untitled

2020

MIJMIC

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Background: Brucellosis is one of the most common zoonotic infections globally. The laboratory confirmation of human Brucellosis is based on microbiological, serological or molecular methods, each having its own advantages and disadvantages. Aim: To study Brucellosis among patients with pyrexia of unknown origin. Materials and Methods: Blood samples from 111 patients with PUO were taken and blood from 50 healthy controls were also collected. All the samples were tested by IgG and IgM ELISA and Standard Agglutination Test (SAT). IgG ELISA results were compared with SAT for Brucellosis. Results: Anti Brucella IgM antibodies were found in 2 (1.80%) and IgG in 4 (3.60%). 3 patients (2.7%) out of 111 patients were positive by SAT.Sensitivity and specificity of IgG and SAT were 100% and 99.07% respectively. PPV (positive predictive value) and NPV (negative predictive value) were 95% and 100% respectively and diagnostic accuracy was 99.09%.Conclusion:Standard Agglutination Test being cumbersome, time consuming and showing false negativity due to blocking antibodies, IgG ELISA and IgM ELISA can be used for diagnosis of Brucellosis.

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“…[21][22] In South and North Karnataka, 2.14%, 0.92% seropositivity was observed respectively among patients with or without fever and those presenting other symptoms for brucellosis 17 . Mangalgi et al 27 conducted a seroepidemiological survey in three districts of Karnataka viz., Bijapur, Bagalkot, and Gulbarga. They divided into two groups namely, directly exposed and indirectly exposed to animal contacts.…”

Section: Seroprevalence Of Brucellosis Among Febrile Patients (Puo)mentioning

confidence: 99%

Seroprevalence of Human Brucellosis in and Around Puducherry: Application of an Immunocapture Agglutination Technique (Brucellacapt)

Spellman¹,

Pradeep²,

Sangeetha³

et al. 2019

J Pure Appl Microbiol

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The objective of the present study was the serological diagnosis of human brucellosis in and around Puducherry by application of Immunocapture-agglutination technique (Brucella Capt), which has been validated and found to be quite satisfactory. The study has included febrile patients, patients with chronic back pain/arthritis, healthy pregnant women, personnel exposed to domestic livestock and voluntary blood donors. Prevalence of brucellosis in these different categories was studied. Overall seroprevalence of brucellosis among different categories of individuals from Puducherry is very low, viz., 3.27%. Among febrile patients, the prevalence is almost the same with 3.33% positivity. Among 100 healthy pregnant women, only one had antibodies to Brucella abortus (1.00%). The category of animal handlers as expected had higher seroprevalence rate of 8.00%. All the 45 voluntary blood donors were seronegative for brucellosis.

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Serological, clinical, and epidemiological profile of human brucellosis in rural India

Cited by 24 publications

References 17 publications

Epidemiological characteristics of human brucellosis in Al-Qassim region, Saudi Arabia, between 2010 and 2014

Epidemiological characteristics of human brucellosis in Al-Qassim region, Saudi Arabia, between 2010 and 2014

Untitled

Seroprevalence of Human Brucellosis in and Around Puducherry: Application of an Immunocapture Agglutination Technique (Brucellacapt)

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