Serological and Biochemical Study of Hepatitis B patients, a Report From the Southeast of Iran

Shahramian, Iraj; Rostami, Daryoush; Sharafi, Elham; Sargazi-Aval, Omolbanin; Delaramnasab, Mojtaba; Bazi, Ali

doi:10.2217/fvl-2017-0102

Cited by 3 publications

(2 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The identification of bacteria in a microbiology laboratory mainly relies on traditional biochemical identification, molecular biology, and morphology methods. [5,6] At present, Gram staining, [7,8] biochemical and serological methods [9][10][11] are mainly used for the detection of drug-resistant strains. However, the identification of biochemical characteristics based on a single colony is time-consuming and vulnerable to external conditions, [12] which cannot meet the clinical requirements like timeliness of detecting.…”

Section: Introductionmentioning

confidence: 99%

Rapid Identification of Polypeptide from Carbapenem‐Resistant and SusceptibleEscherichia colivia Orbitrap‐MS and Pattern Recognition Analyses

Sun

Wang

et al. 2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

A rapid and accurate analytical method was established to identify CREC and CSEC. Orbitrap-MS was used to detect the polypeptide of CREC and CSEC strains, and MS data were analyzed by pattern recognition analyses such as hierarchical cluster analysis (HCA), principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA), and orthogonal partial least squares discriminant analysis (OPLS-DA). HCA based on the farthest distance method could well distinguish the two types of E. coli, and the cophenetic correlation coefficient of the farthest distance method was 0.901. Comparing the results of PCA, PLS-DA, and OPLS-DA, OPLS-DA exhibited the highest accuracy in predicting the CREC and CSEC strains. A total of 26 compounds were identified, and six of the compounds were the highly significant difference between the two types of strains. MS combined with pattern recognition can achieve a more comprehensive and efficient statistical analysis of complex biological samples.

show abstract

Section: Introductionmentioning

confidence: 99%

Rapid Identification of Polypeptide from Carbapenem‐Resistant and SusceptibleEscherichia colivia Orbitrap‐MS and Pattern Recognition Analyses

Sun

Wang

et al. 2022

Chemistry & Biodiversity

View full text Add to dashboard Cite

show abstract

“…Nevertheless, these patients may present with non-specific digestive symptoms and pain in upper quadrat of stomach. Unlike hepatitis B (HBV) or hepatitis C (HCV) infections, affecting of other body systems besides liver is not common in HAV infection (2). However, tissues such as lymph nodes, muscles, skin, as well as kidneys have scarcely been among target organs in HAV infection (3).…”

Section: Introductionmentioning

confidence: 99%

Hepatitis A Infection Presented with Pancytopenia, a Case Series in Children

et al. 2019

Self Cite

View full text Add to dashboard Cite

Introduction: Extrahepatic presentation in hepatitis is a relatively uncommon clinical condition. In particular, pancytopenia related to hepatitis is a rare phenomenon encountered in these patients. Pancytopenia can be associated with a variety of hepatitis viruses; however, its association with hepatitis A virus (HAV) is unusual. Case Presentation: In current case series, we reported 11 children who presented with three suppressed blood lineages, including white blood cells, platelets, reticulocytes, and hemoglobin with mean values of 2.4 × 103/µL, 54.5 × 103/µL, 1%, and 9.4 g/dL. Of these 11 children, 5 were boys. The mean age was 6.5 years old. The patients presented with abdominal pain, hepatitis, and pallor. Biochemical analysis showed liver function enzymes were increased in all patients. Serologic studies for antibodies against viral components, including hepatitis B (HBV), hepatitis C (HCV), and HAV, as well as cytomegalovirus (CMV) showed positive results for anti-HAV IgM. Coombs tests were negative in all the patients. Conclusions: Clinicians should consider extrahepatic presentations of hepatitis infections, especially HAV infection that may present with non-specific clinical features. This can help health care providers to timely and correct diagnosis and treatment of this infection.

show abstract

A Review on Clinical, Pathophysiological, and Diagnostic Hematological Features in Children With Liver Cirrhosis

Shahramian

Tabrizian

Delaramnasab

et al. 2019

Int J Basic Sci Med

Self Cite

View full text Add to dashboard Cite

Appropriate diagnostic and therapeutic measures for liver cirrhosis is critical, particularly in children. In the present review, a comprehensive approach was provided toward hematological parameters in pediatric liver cirrhosis. The literature search included MeSH terms "liver cirrhosis" and "hepatic cirrhosis" and databases such as PubMed, Web of Science, Scopus, and Google Scholar were searched up until December 2017. Hematologic changes in the liver cirrhosis mainly encompassed anemia and coagulopathies. In addition, bleeding diathesis was considered as the most clinical complication in these patients. In addition to reduced coagulation factors, hyperfibrinolysis is a common feature in childhood cirrhosis and may be an important contributor to the risk of bleeding. Based on the results, children with liver cirrhosis also demonstrated a procoagulant state at laboratory and clinical levels. This may be partly due to a reduction in coagulation inhibitors such as anti-thrombin, C1 inhibitor, and α1-antitrypsin in children with cirrhosis. The portal vein thrombosis and portal hypertension are considered as the most clinical presentations of the hypercoagulable state. Further, children with liver cirrhosis complicated with portal hypertension usually show leukopenia, anemia, and thrombocytopenia due to hypersplenism. Although the etiology of childhood and adult cirrhosis may be different, their hematological compilations and clinicopathological features are somehow similar.

show abstract

Serological and Biochemical Study of Hepatitis B patients, a Report From the Southeast of Iran

Cited by 3 publications

References 17 publications

Rapid Identification of Polypeptide from Carbapenem‐Resistant and SusceptibleEscherichia colivia Orbitrap‐MS and Pattern Recognition Analyses

Rapid Identification of Polypeptide from Carbapenem‐Resistant and SusceptibleEscherichia colivia Orbitrap‐MS and Pattern Recognition Analyses

Hepatitis A Infection Presented with Pancytopenia, a Case Series in Children

A Review on Clinical, Pathophysiological, and Diagnostic Hematological Features in Children With Liver Cirrhosis

Contact Info

Product

Resources

About