Seroepidemiology of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in wild mice captured in Northern Turkey

Abstract

An expedition across the Asian part of the Black Sea coast and national parks of Northern Turkey was organized in the summer of 2001 to investigate the presence of Borrelia burgdorferi sensu lato (s.l.), Lyme borreliosis agent, and Anaplasma phagocytophilum, human granulocytic ehrlichiosis, agent, in wild mice. A total of 65 Apodemus flavicollis, Apodemus sylvaticus, Microtus epiroticus, Crocidura suaveolens and Mus macedonicus, were captured. Two out of 22 Apodemus sylvaticus specimens were seropositive for B. afzelii by enzyme-linked immunosorbent assay as confirmed by Western blotting, however cultures of skin and bladder samples from all small mammals in Barbour-Stoenner-Kelly's medium-II remained negative for B. burgdorferi s.l. All sera tested were negative for Anaplasma phagocytophilum by indirect immunofluorescent assay. The prevalence of B. burgdorferi s.l. and Anaplasma phagocytophilum is low in wild mice of the Asian part of Northern Turkey.

Anaplasma phagocytophilum—a widespread multi-host pathogen with highly adaptive strategies

“…In Korea, prevalence rates in the black-striped field mouse was also up to 23.6% (Kim et al, 2006) and therefore, A. agrarius has been discussed as one of the major reservoir host in Asian countries. In the Asian part of Turkey, however, all captured rodents were serologically negative for A. phagocytophilum (Güner et al, 2005). …”

Lyme Disease

“…[5] tarafından 2010 yılında bildirilmiştir. Türkiye'den bazı seroepidemiyolojik çalışmalar Tablo 1'de sunulmuştur [6,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] . Ülkemizde hastalık bildirimi zorunlu hastalıklar kategorisine alınarak "Klinik Bakteriyoloji Tanı Standartları Çalışma Grubu" tarafından referans laboratuvar özellikleri standardize edilmiş ve Türkiye Halk Sağlığı Kurumu tarafından düzenlenmiştir [31] .…”

“…Tablo 1. Türkiye'de insan, kene, fare ve atlarda yapılan bazı seroepidemiyolojik çalışmalar [6,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] Yazar/referans Çalışma türü Coğrafi bölge…”

Türkiye’de Atlarda anti-Anaplasma phagocytophilum Antikorlarının İlk Tespiti

“…Many available studies conducted on A. phagocytophilum infection on horses were present [20][21][22][23][24][25] . In Turkey, although studies conducted on A. phagocytophilum including a wide variety of animal species such as cattle, sheep, dog, mice, besides human [26][27][28][29][30][31][32] were exist, but there is no report about equine anaplasmosis. The aim of this study was to detect anti-A.…”