Seroepidemiology of Helicobacter pylori in primary school students in Krotek, Cibeber Village, Serang District, Banten, Indonesia

Abstract

Background Helicobacter pylori infection is a common infection.Risk of infection in rural areas is six times higher than in urbanareas.Objectives To study the prevalence of H. pylori infection in primary school students in rural area and its contributing factors.Methods A cross-sectional study was performed in a rural primaryschool in Serang district, Banten, West Java. Serology of H. pyloriwas tested using Bio M pylori kit (Mataram, Indonesia).Results Forty two of 125 subjects (33.6%) had positive H. pyloriserologies. Bivariate analysis found that the the family habit ofeating together from one container increased the infection risk5.93 times (95% Cl 3.07 to 11.43). Source of drinking waterfrom common river increased the risk 9.88 times (95% CI 3.03to 32.24). Bed and bedroom sharing increased the risk 1.55 times (95% CI 1.23 to 1.95) and 2.22 times (95% CI 1.65 to 2.99), respectively. Multivariate logistic regression analysis including all variables with P <0.25 showed that the most significant factor contributing to H. pylori infection is common river as family drinking water source (OR 24.97, 95% CI 3.9 to 159.76), followed by family habit of eating together from one container (OR 10.23, 95% CI 3.05 to 34.27), and bed or bedroom sharing (OR 9.48, 95% CI 2.4 7 to 36.38).Conclusion Prevalence of H. pylori infection in rural schoolstudents is 33.6%. There are significant associations betweenH. pylori infection and family habit of eating together from onecontainer, bed sharing with other family members, and familydrinking water source from common river.

Prevalensi Infeksi Helicobacter pylori pada Anak dengan Gejala Gastrointestinal di Rumah Sakit Umum Pusat Dr. Sardjito Yogyakarta

“…Penelitian lain menunjukkan prevalensi infeksi H. pylori sebesar 33,6% dari 125 anak sekolah dasar di Serang, Banten, berusia 6-12 tahun dengan metode pemeriksaan antibodi serum. 12 Penelitian Dewita dkk 11 dilakukan di Jakarta pada anak usia 12-15 tahun dari 5 sekolah dengan keluhan nyeri perut berulang, dari 60 anak didapatkan 8% dengan pemeriksaan UBT dan 52% dengan pemeriksaan serologis. Penelitian Hegar 20 Penelitian Zabala dkk 10 menunjukkan bahwa prevalensi infeksi H. pylori pada anak yang bergejala secara histologis dengan endoskopi sangat bervariasi antara penelitian satu dengan yang lain, berkisar antar 3-76%, dengan rata-rata sekitar 39%.…”

“…Hasil penelitian-penelitian tersebut bervariasi, di antaranya penelitian di Manado menunjukkan prevalensi infeksi H. pylori pada anak sebesar 3,8%, sementara di Jawa Barat sebesar 52%. 11,12 Inflamasi pada lambung anak yang terinfeksi H. pylori memiliki karakteristik lebih sedikit infiltrasi sel polimorfonuklear dan mononuklear, insidensi ulserasi gaster dan duodenum lebih rendah dan epitel yang lebih intak daripada dewasa. Konsekuensinya adalah bentuk ulserasi pada lambung anak sangat jarang didapatkan.…”