Sero-prevalence of respiratory syncytial virus infection in children (0-5 years) attending institute of child health Banzazzau Zaria Kaduna State

Abstract

Serological survey was carried out among children attending Institute of Child Health (ICH) Banzazzau Zaria Kaduna, State, to determine the prevalence of Respiratory Syncytial Virus IgM antibodies. Ninety-one blood samples of children aged 0 clinic of Ahmadu Bello University Teaching Hospital Zaria (ICH Banzazzau). Respiratory s virus IgM antibody level was measured using commercial ELISA kit obtained from DIAGNOSTIC AUTOMATION, INC. Of the ninety seropositive for Respiratory Syncytial Virus. There was male predominan positive compared in females 20 (22.0%) although, the difference was not statistically significant (P value >0.05).The seroprevalence was highest (15.4%) among infants 0 (5.5%) among 3 years old children..The asso symptoms was not statistically significant. Every child who showed seropositivity with the Respiratory Syncytial Virus had fever and no child without a fever was diagnosed positive with the virus. This study has revealed that children aged 0 Zaria, and therefore, highlighting the need for the younger age group to be targeted for prevention programme against RSV infection.

Seroprevalence and molecular characterization of human respiratory syncytial virus and human adenovirus among children in Ado‐Ekiti, Nigeria

“…The statistical association between RSV IgM and gender, age, or any of the symptoms considered was not significant ( p > 0.05). Similar reports by previous researchers had shown that gender was not significantly associated with susceptibility to HRSV infection 30,31 . Also similar to this study, no statistical association between age, respiratory infection symptoms, and RSV infection was reported by Sulaiman et al 31 …”

“…A low seroprevalence was recorded for RSV IgM with 15/200 (7.5%) among the studied children. In contrast, a similar study reported a higher seroprevalence of RSV IgM (47.3%) among children in Zaria, Nigeria 31 . The statistical association between RSV IgM and gender, age, or any of the symptoms considered was not significant ( p > 0.05).…”

Respiratory Syncytial Virus Infection among Children in Lagos, Nigeria

“…This is in tandem with studies from Nigeria and other part of the world where fever and cough were reported as the commonest symptoms seen in ALRTIs caused by RSV [22]. In Ibadan, fever was seen in 78% while cough was seen in 82% of ALRTIS caused by RSV [20]. Similarly, a study conducted in Zaria found that fever and cough were seen in 82% and 79% of children with RSV infection respectively [25].…”

“…This prevalence obtained is close to 23.5% reported in a sero-epidemiological study of respiratory syncytial virus among children in Ibadan, South West, Nigeria [19]. However, this finding is lower than 34.6% reported in another study in Ibadan among children attending secondary health facility for ALRTIs [20]. In Abeokuta a prevalence of 5.4% was reported among children under the age of five years attending paediatric outpatient for ALRTI [21].…”

“…In studies conducted in Ghana and Kenya among hospitalized children, the highest prevalence was reported in children aged 0-6 months [17]. A slight deviation from this is a study conducted [13,20,22,23]. The reasons attributable to varied prevalence among different age groups may be due to disparity in number of children that were recruited in the various studies.…”