Sero-prevalance of HIV antibodies in pregnant women in Port Harcourt

Akani, Chris; Ojule, AC; Opurum, H C; John, CT

doi:10.4314/njm.v15i1.37114

Cited by 26 publications

(27 citation statements)

References 1 publication

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“…This is similar to 7.3% recorded at Port Harcourt but far higher than 0.4% recorded in an India hospital [8,17]. One major reason for this might be that these women have promiscuous husbands.…”

Section: Discussionsupporting

confidence: 62%

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Seroprevalence of HIV among blood donors, antenatal women and other patients in a tertiary hospital in Nigeria

Olajubu¹,

Osinupebi²,

Deji-Agboola³

et al. 2009

Braz J Infect Dis

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HIV/AIDS continues to remain a nightmare in the developing nations of the world especially in Nigeria, where about 2.9 million people are living with this problem. This study aimed at determining the sero-prevalence of HIV among both patients and blood donors at the Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. Samples were collected between January 1st, 2005 and December, 31st 2006 and were screened using two rapid test kits, with two different principles (enzymatic and agglutination). Samples positive to the two methods were taken as truly sero-positive. The seropositive rate among blood donors, antenatal women, in-and out patients were, 3.2%, 6.9% and 17.5% respectively. There were five cases of positivity to both HIV I and II. Antenatal women between the ages of 26-35 were found responsible for 5.3% of the total positivity among antenatal women. Though, there is high prevalence rate among in-and out-patients, many of these were screened based on manifestation of clinical symptoms. However, more is to be done in the area of prevention of this disease, since no cure is yet found.

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Section: Discussionsupporting

confidence: 62%

“…Heterosexual act is responsible for 80% of HIV infections in Nigeria. This is in contrast to what prevail in developed countries where the spread is mainly through homosexuality and injectables [8,17]. The zero positivity recorded among ages 15-20 agrees with some other works [8].…”

Section: Discussioncontrasting

confidence: 47%

Seroprevalence of HIV among blood donors, antenatal women and other patients in a tertiary hospital in Nigeria

Olajubu¹,

Osinupebi²,

Deji-Agboola³

et al. 2009

Braz J Infect Dis

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“…Although this classification gives a fair picture of the global HBV endemicity, it fails to take into account the variability of the disease within various professional groups 1,6,13 . Also, most of information of HBV prevalence in Nigeria is available from blood donors 5,15 .…”

Section: Discussionmentioning

confidence: 99%

High prevalence of hepatitis B virus among female sex workers in Nigeria

Forbi¹,

Onyemauwa²,

Gyar³

et al. 2008

Rev. Inst. Med. trop. S. Paulo

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SUMMARYHepatitis B virus (HBV) infection is endemic in Nigeria and constitutes a public health menace. The prevalence of HBV infection in many professional groups has been described in Nigeria. However, literature on HBV infection among female sex workers (FSW) in Nigeria is scanty. FSW in Nigeria are not subjected to a preventive control of HBV infection. This study assesses the extent of spread of HBV among FSW in Nigeria. Seven hundred and twenty (n = 720) FSW (mean age = 26.7 years) were tested for hepatitis B surface antigen (HBsAg) by a double antibody sandwich ELISA method. The overall HBV prevalence among the FSW was 17.1%. FSWs between the ages of 31-35 year (20.5%) and those with 'age-at-first-sex' below 10 years of age (28%) were most affected. This high prevalence of a vaccine preventable disease is unacceptable, therefore, vaccination of this high risk HBV reservoir group should be considered worthwhile.

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“…Prevalence varies greatly in different parts of the world, but is higher in tropical regions causing both acute and chronic liver disease [2] . In Nigeria, 11.6% prevalence rate has been reported from Maiduguri [3] , 13.8% from Lagos [4] , 4.3% from Port Harcourt [5] , 5.7% from Ilorin [6] , 8.3% from Zaria [7] , 17.1% from female sex workers, 14.9% [8] from healthy blood donors [9] and 25.7% among surgeons [10] . Although HBV prevalence varies widely across the African continent, hepatitis B surface antigen (HBsAg) positivity is estimated at 8-20% [11] .…”

Section: Introductionmentioning

confidence: 99%

Experience with Hepatitis B viral load testing in Nigeria

Okwuraiwe¹,

Salu²,

Onwuamah³

et al. 2011

Af J Clin Exp Micro

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Background: Quantification of the viral burden is an important laboratory tool in the management of hepatitis B virus (HBV)-infected patients. However, widespread use of assays is still hampered by the high cost. Treatment reduces viral load to undetectable levels. HBV infected patients tend to have high HBV DNA levels, and severe liver disease. Objectives: This study was carried out to determine the pattern of HBV viral load levels of patients assessing management in Nigeria. Method: Variables included sociodemographics like age, sex, religion, income, educational background and residence. The COBAS Amplicor automated Analyzer (PCR based) was used to assay the virus quantitatively.Results: 594 patients were tested from 2008 to 2009. Statistical analysis was done using Epi info version 2002 and test of significance by Kruskal-Wallis. Mean age of the patients was 36.8 (ranging from 9 to 69) years. HBV viral titre ranged between 4,145 and 68,011,800 DNA copies/ml. Conclusion: There was a high occurrence of viral titre in the population studied. High viral load is a risk factor for hepatocellular carcinoma. A policy earmarked to combat this virus in Nigeria is hereby solicited.

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Sero-prevalance of HIV antibodies in pregnant women in Port Harcourt

Cited by 26 publications

References 1 publication

Seroprevalence of HIV among blood donors, antenatal women and other patients in a tertiary hospital in Nigeria

Seroprevalence of HIV among blood donors, antenatal women and other patients in a tertiary hospital in Nigeria

High prevalence of hepatitis B virus among female sex workers in Nigeria

Experience with Hepatitis B viral load testing in Nigeria

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