Background: Blood donation is a very important life saving intervention in health care services. It is also known that some diseases are transmitted from the seemly healthy blood donors like HIV, Hepatitis B, Hepatitis C and Syphilis and WHO has recommended that these diseases should be screened to get safe blood. Since screening of blood donors is done in this health facility, it is therefore necessary to know the prevalence of HIV, HBV, HCV and syphilis in these blood donors. This study aimed at determining the seroprevalence of HIV, HBV, HCV and Syphilis in prospective blood donors in our health institution. Methodology: This was a retrospective study. The records of the blood donors were reviewed and Biodata and positivity of the diseases were collected. Data was analyzed with Excel and Epi-info. Results: The total of 2626 blood donors were recruited in 2012 out of which 2292 (87.3%) were males, 271 (10.3%) females, .7397] and 63, undocumented gender (2.4%). Majority of the donors were within the age group 29-39 (43.3%, N=1143). The seroprevalance of HIV, HBV, HCV and Syphilis were 0.3% (N=8), 0.3% (N=8), 0.2% (N=5), 0.1% (N=3) respectively. All the cases were males.
Conclusion:The study revealed a low prevalence of transfusion transmissible infectious agents among our prospective blood donors. It could be that people who know their status do not come for blood donation or as a result of other challenges confronting safe blood practices in sub-Saharan Africa.