Sero-Epidemiological Studies of Malaria in Indian Tribes and Monkeys of the Amazon Basin of Brazil

Arruda, Maria Augusta; Nardin, Elizabeth; Nussenzweig, R S; Cochrane, Alan H.

doi:10.4269/ajtmh.1989.41.379

Cited by 60 publications

(45 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Brazil, there is evidence that asymptomatic or oligosymptomatic malaria cases may also occur in certain endemic areas (Prata et al 1988, Silva et al 1993, Malafronte et al 1994. Arruda et al (1989) in a seroepidemiological study of malaria in several Indian tribes in Brazil, found a high prevalence of anti-plasmodial antibodies, while parasites were only rarely found in their blood. A high prevalence of anti-P. malariae /P.…”

Section: Discussionmentioning

confidence: 99%

Antibodies anti Bloodstream and Circumsporozoite Antigens (Plasmodium vivax and Plasmodium malariae/P. brasilianum) in Areas of Very Low Malaria Endemicity in Brazil

Curado

Duarte

Lal

et al. 1997

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Antibodies anti Bloodstream and Circumsporozoite Antigens (Plasmodium vivax and Plasmodium malariae/P. brasilianum) in Areas of Very Low Malaria Endemicity in Brazil

Curado

Duarte

Lal

et al. 1997

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

show abstract

“…The probable role of neotropical primates as reservoirs and their role in the epidemiological chain of human malaria have been discussed, but the natural transmission cycles from primate vectors to humans have not yet been fully established (ARRUDA et al, 1989;DUARTE et al, 2008;YAMASAKI et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Natural Plasmodium infection in neotropical primates in the island of São Luís, state of Maranhão, Brazil

Figueiredo

Santi²,

Figueiredo

et al. 2015

Rev. Bras. Parasitol. Vet.

View full text Add to dashboard Cite

The states that make up the Legal Amazon Region, which include the state of Maranhão, account for 99% of registered cases of human malaria in Brazil. It is also believed that transmission of malaria from nonhuman primates (NHP) to humans occurs in this region, because of current reports of seroepidemiological results from samples from humans and NHP coexisting in the same areas. This study aimed to make morphological, serological and molecular diagnoses of Plasmodium spp. in neotropical primates on the island of São Luís, state of Maranhão, Brazil. The diagnostic techniques used were optical microscopy, the polymerase chain reaction (PCR) and the indirect immunofluorescence assay (IFA). From June 2009 to April 2010, 70 NHP were sampled: 50 at the Wild Animal Screening Center (CETAS), located in the municipality of São Luís and 20 free-living individuals that were caught in a private reserve located in the municipality of São Jose de Ribamar, state of Maranhão. Under an optical microscope, 140 slides (two from each animal) were evaluated and five animals (7.1%) were found to be positive. IFA did not detect anti-Plasmodium spp. From PCR on the 70 animals sampled, amplified Plasmodium spp. products were observed in 13 samples, of which eight (61.5%) were from free-living animals and five (38.5%) were from animals at CETAS.

show abstract

“…In a study in Asembo Bay, Kenya, 59% of persons had antibodies to the peptide; all positivity rates increased with age (43). In a seroepidemiologic study conducted on Indian tribes in the Amazon Basin of northern Brazil, Arruda et al (41) found that almost all Metuktire and almost 90% of the Asurini adults had antisporozoite antibodies against P. brasilianum/P. malariae.…”

Section: Serologic Studiesmentioning

confidence: 99%

Plasmodium malariae : Parasite and Disease

2007

View full text Add to dashboard Cite

SUMMARY A review of the life history of Plasmodium malariae, the quartan malaria parasite of humans, is presented. Much of the information is based on data obtained from induced infections in humans who were given malaria therapy for the treatment of neurosyphilis between 1940 and 1963. Prepatent periods (i.e., the time until the first day of parasite detection) fever episodes, and maximum parasitemias as a result of infection with P. malariae were obtained and are presented. Experimental and known vectors of the parasite are also discussed. Splenectomized chimpanzees and New World monkeys are readily infected and serve as sources of parasites and antigens for diagnostic and molecular studies. South American monkeys are naturally infected with a parasite known as Plasmodium brasilianum. This parasite appears to be P. malariae that has adapted from humans to grow in monkeys, probably within the last 500 years. Infection with P. malariae is associated with the production of immune complexes in the kidneys and the associated nephrotic syndrome. The essential lesions are a thickening of the glomerular basement membrane and endocapillary cell proliferation. Studies of monkeys infected with P. malariae indicate the same pathology as that demonstrated in humans.

show abstract

Sero-Epidemiological Studies of Malaria in Indian Tribes and Monkeys of the Amazon Basin of Brazil

Cited by 60 publications

References 0 publications

Antibodies anti Bloodstream and Circumsporozoite Antigens (Plasmodium vivax and Plasmodium malariae/P. brasilianum) in Areas of Very Low Malaria Endemicity in Brazil

Antibodies anti Bloodstream and Circumsporozoite Antigens (Plasmodium vivax and Plasmodium malariae/P. brasilianum) in Areas of Very Low Malaria Endemicity in Brazil

Natural Plasmodium infection in neotropical primates in the island of São Luís, state of Maranhão, Brazil

Plasmodium malariae : Parasite and Disease

Contact Info

Product

Resources

About