Serial quantitative skin surface fluorescence: A new method for postoperative monitoring of vascular perfusion in revascularized digits

Graham, Braun H.; Gordon, Lewis R.; Alpert, Bernard S.; Walton, Robert; Buncke, Harry J.; Leitner, David W.

doi:10.1016/s0363-5023(85)80109-x

Cited by 32 publications

(12 citation statements)

References 7 publications

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“…Free tissue transfer/replant monitoring Postoperative monitoring of revascularized or replanted digits has been previously reported using serial quantitative skin fluorescein measurements [7]. However, we were the first to report on the use of laser induced fluorescence for peri-and postoperative monitoring of free flaps [15].…”

Section: Determination Of Burn Depthmentioning

confidence: 88%

Laser-induced fluorescence of indocyanine green: plastic surgical applications

et al. 2003

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The objective assessment of tissue perfusion is of utmost importance to plastic surgeons. Nevertheless, clinical observation remains the accepted gold standard for assessment of microcirculation. Dynamic laser fluorescence videography is a new technique for objective assessment of blood flow. We describe our clinical experience using this technique in plastic surgical patients. Possible implementations include evaluation of pedicle (random and axial pattern) flaps, monitoring of free tissue transfer and replants, and the objective determination of burn depth. Compared with standard clinical assessment techniques indocyanine green imaging provides significant additional information which allows a rational and evidence-based planning of surgery.

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Section: Determination Of Burn Depthmentioning

confidence: 88%

Laser-induced fluorescence of indocyanine green: plastic surgical applications

et al. 2003

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“…Drawbacks include the requirement for fluorescein mixing and injection, the labor-intensiveness of 3 measurements per hour, and the small risk of side effects. 9,10 Currently there are no commercially available fluoroscopes for clinical use in replantation.…”

Section: Discussionmentioning

confidence: 99%

“…9 Briefly, sodium fluorescein was administered intravenously every 2 hours after surgery. Quantitative fluorescence readings of the injured and control digits were assessed 0, 10, and 60 minutes after fluorescein injection.…”

Section: Quantitative Skin Fluorescencementioning

confidence: 99%

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Detection of Perfusion Disturbances in Digit Replantation Using Near-Infrared Spectroscopy and Serial Quantitative Fluoroscopy

Colwell

Buntic

Brooks

et al. 2006

The Journal of Hand Surgery

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“…Light propagation in tissue is governed by the diffusion equation (a partial differential equation) and can be analytically solved in some special cases 8 Physiological properties of tissue, such as StO2 and Hgb, can be determined by analyzing measurement data of the exiting NIR light . 3.1 Description of the study The clinical study was conducted in the California Pacific Medical Center (CPMC) from March 4, 2003 to September 4, 2004. Total of forty-eight (48) patients were enrolled in the study with demographics given in Table I .…”

Section: The Test Devicementioning

confidence: 99%

Application of near-infrared spectroscopy in monitoring blood perfusion in digital replantation

Mao

Wright

Elmandjra

2005

Advanced Biomedical and Clinical Diagnostic Systems III

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Using a near-infrared optical device developed by ViOptix, Inc., a clinical study on post-operative non-invasive monitoring of fmger blood perfusion has been conducted for 48 patients undergoing digital replantation at the California Pacific Medical Center. The study showed that non-survival digits have their tissue oxygen saturation (St02) values significantly lower than those for the controls in general, but survival digits did not. Further, the St02 values can be used to defme a survival index, in terms of which a digit survival criterion was tentatively suggested. Applying the criterion to the 64 digits (with 3 of them non-survival) involved in the clinical study, the sensitivity and the specificity were high. Therefore the device may have potential to be used in post-operative monitoring for digit replantation.

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Serial quantitative skin surface fluorescence: A new method for postoperative monitoring of vascular perfusion in revascularized digits

Cited by 32 publications

References 7 publications

Laser-induced fluorescence of indocyanine green: plastic surgical applications

Laser-induced fluorescence of indocyanine green: plastic surgical applications

Detection of Perfusion Disturbances in Digit Replantation Using Near-Infrared Spectroscopy and Serial Quantitative Fluoroscopy

Application of near-infrared spectroscopy in monitoring blood perfusion in digital replantation

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