Serial intraocular lens opacifications of different designs from the same manufacturer: Clinical and light microscopic results of 71 explant cases

Gurabardhi, Maceda; Häberle, H; Aurich, H; Werner, Liliana; Pham, Duy-Thoai

doi:10.1016/j.jcrs.2018.07.026

Cited by 43 publications

(71 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Visually significant calcification has been reported with some IOLs made of the same copolymer material as the high-add implant [12,13]. Although we did not encounter any such reactions, our series is small and longer follow-up is needed because the opacity may develop after 4 years [12,13].…”

Section: Discussionmentioning

confidence: 60%

Four Years of Observation to Evaluate Autonomy and Quality of Life after Implantation of a High-Add Intraocular Lens in Age-Related Macular Degeneration Patients

Borkenstein

2020

Case Rep Ophthalmol

View full text Add to dashboard Cite

Visual impairment resulting from advanced dry age-related macular degeneration (AMD) limits the ability to perform activities required for independent living and adversely affects quality of life. We aimed to determine changes in these parameters in patients with AMD-related geographic atrophy who underwent magnifying cataract surgery (MAGS) using a foldable, bifocal high-add intraocular lens (IOL). The high-add IOL (LENTIS ® MAX LS-313 MF 80, Oculentis) was implanted in the better seeing or dominant eye of eligible patients with clinically significant cataract, best corrected distance visual acuity 1.3-0.5 logMAR (20/400-20/63), best corrected near visual acuity >0.8 logMAR (20/125), and stable advanced dry AMD. Self-reported feasibility of performing routine activities and change in quality of life were the main outcome

show abstract

Section: Discussionmentioning

confidence: 60%

Four Years of Observation to Evaluate Autonomy and Quality of Life after Implantation of a High-Add Intraocular Lens in Age-Related Macular Degeneration Patients

Borkenstein

2020

Case Rep Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Another factor that may increase the risk of IOL surface opacification is the type of material. Most of the included studies employed hydrophilic acrylic lenses, and, in their conclusions, they discouraged the use of this type of lens when carrying out the aforementioned interventions . In this review, we evaluated whether the different characteristics of the lenses used could be a factor that could influence lens opacification.…”

Section: Discussionmentioning

confidence: 99%

“…Of the 45 articles, five did not fulfil the inclusion criteria and were excluded from further analysis. The remaining included articles numbered 40 and were analysed using the Pierson tool …”

Section: Methodsmentioning

confidence: 99%

Systematic review of potential causes of intraocular lens opacification

Fernández

Sánchez‐García

Rodríguez‐Vallejo³

et al. 2019

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

Intraocular lens (IOL) opacification is an infrequent complication of cataract sur-gery. Surface analysis has demonstrated that the opacification of IOLs is related to calcium or phosphate precipitation on or within the lenses, but the associated mechanisms are unknown, and the scientific literature is heterogeneous and limited to case series and retrospective studies. The purpose of this systematic review was to analyse the most frequent conditions associated with opacification of IOLs reported by studies. A search was carried out using the PubMed MEDLINE, Web of Science and Scopus databases. The quality of the studies selected was evaluated using the Pierson tool. The search provided a total of 811 articles, of which 39 were selected following the inclusion and exclusion criteria. The most common opacified lenses were hydrophilic IOLs according to our analysis. The mean time of appearance of lens opacification was 14.93 ± 17.82 months. The most frequent conditions associated with opacification of the IOLs were Descemet Stripping with Automated Endothelial Keratoplasty (DSAEK/DSEK) and diabetes mellitus (DM), followed by pars plana vitrectomy (PPV), blood hypertension (HT), and glaucoma.Concerning the quality analysis, the mean score was 7.00 ± 1.43 (scoring range from 0 to 10), indicating an acceptable quality of the case reports and retrospective studies. In conclusion, DSAEK/DSEK, DM, PPV, glaucoma and hypertension are conditions with potential risk of IOL opacification after cataract surgery, especially when implanting hydrophilic acrylic IOLs. K E Y W O R D Sacrylic IOL, cataract surgery, intraocular lens, IOL explantation, IOL opacification

show abstract

“…While hydrophilic acrylic IOLs are not very popular in the United States, they are still widely used in many European countries, including Poland and Germany [15]. Therefore, the complication may still potentially arise in a certain group of pseudophakic patients who have already received hydrophilic acrylic IOL models and who will need DSAEK or Descemet's membrane endothelial keratoplasty (DMEK) in the future owing to acquired endothelial dysfunction.…”

Section: Medical Backgroundmentioning

confidence: 99%

“…Although the incidence of opacification of hydrophilic acrylic IOLs after DSAEK reaches 5-9% [9,10], it is worth noting that IOL replacement is much less frequently performed in eyes after DSAEK than in eyes with a healthy cornea, where it is a treatment of choice, with good visual results [15]. In patients with less advanced opacity, the management is often limited to observation only.…”

Section: Potential Impact On Current Medical Practicementioning

confidence: 99%

Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

et al. 2020

View full text Add to dashboard Cite

An intraocular lens (IOL) is a synthetic, artificial lens placed inside the eye that replaces a natural lens that is surgically removed, usually as part of cataract surgery. The opacification of the artificial lens can be related to the formation of the sediments on its surface and could seriously impair vision. The physicochemical analysis was performed on an explanted hydrophilic IOL and compared to the unused one, considered as a reference IOL. The studies were carried out using surface sensitive techniques, which can contribute to a better understanding of the sedimentation process on hydrophilic IOLs’ surfaces. The microscopic studies allowed us to determine the morphology of sediments observed on explanted IOL. The photoelectron spectroscopy measurements revealed the presence of organic and inorganic compounds at the lens surface. Mass spectroscopy measurements confirmed the chemical composition of deposits and allowed for chemical imaging of the IOL surface. Applied techniques allowed to obtain a new set of information approximating the origin of the sediments’ formation on the surface of the hydrophilic IOLs after Descemet’s stripping endothelial keratoplasty.

show abstract

Serial intraocular lens opacifications of different designs from the same manufacturer: Clinical and light microscopic results of 71 explant cases

Cited by 43 publications

References 32 publications

Four Years of Observation to Evaluate Autonomy and Quality of Life after Implantation of a High-Add Intraocular Lens in Age-Related Macular Degeneration Patients

Four Years of Observation to Evaluate Autonomy and Quality of Life after Implantation of a High-Add Intraocular Lens in Age-Related Macular Degeneration Patients

Systematic review of potential causes of intraocular lens opacification

Physicochemical Analysis of Sediments Formed on the Surface of Hydrophilic Intraocular Lens after Descemet’s Stripping Endothelial Keratoplasty

Contact Info

Product

Resources

About