Seqüestro pulmonar extralobar: análise anatomopatológica de dois casos em natimortos e revisão da literatura

Sequestro pulmonar e tratamento endovascular: um relato de caso

“…1 Of these, pulmonary sequestration accounts for 0.15 to 6.45% of pulmonary malformation cases. [1][2][3] Pulmonary sequestration is thus a rare congenital anomaly. It consists of a non-functional mass of pulmonary parenchyma that does not communicate with the normal tracheobronchial tree and which receives its blood supply from an anomalous systemic artery, generally from the descending aorta, although other sources of arterial supply are possible.…”

“…Drainage may be via systemic veins or pulmonary veins. [1][2][3] The tissue is embryonic cystic tissue and non-aerated and disorganized alveoli, in addition to other respiratory tract components. 1 The malformation can be classified as one of two distinct forms, intralobar or extralobar, on the basis of whether it has its own pleural envelope.…”

“…1 The malformation can be classified as one of two distinct forms, intralobar or extralobar, on the basis of whether it has its own pleural envelope. [1][2][3] Intralobar pulmonary sequestration is present when the sequestrated area is surrounded by the visceral pleura of a normal pulmonary lobe. [1][2][3] This form accounts for approximately 75% of sequestration cases, and most commonly involves the inferior left lobe, with equal distribution by sex.…”

“…[1][2][3] Intralobar pulmonary sequestration is present when the sequestrated area is surrounded by the visceral pleura of a normal pulmonary lobe. [1][2][3] This form accounts for approximately 75% of sequestration cases, and most commonly involves the inferior left lobe, with equal distribution by sex. Intralobar cases tend to have later clinical manifestation, during the second decade of life, generally with recurrent respiratory infections, hemoptysis, and dyspnea.…”

“…1,3 In extralobar pulmonary sequestration, the sequestrated region is surrounded by its own pleural envelope, accounting for the remaining 25% of cases of this type of pulmonary malformation. [1][2][3] This form also predominantly involves the left lower lobe, but, in contrast with intralobar sequestration, prevalence is higher in males (4:1). 2,3 Clinical presentation tends to occur in the first few months of life and it is often associated with other congenital malformations, the most common being diaphragmatic hernia.…”