Sequelae After Involution of Superficial Infantile Hemangioma: Early Intervention with 595-nm Pulsed Laser Combined with 755-nm Long-Pulsed Alexandrite Laser versus Wait-and-See

Jiang, Ji‐Cong; Xu, Qin; Fang, Shiji; Gao, Yu; Jin, Wanwan

doi:10.2147/ccid.s279140

Cited by 9 publications

(3 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This also suggests that early active intervention for IH can lead to better therapeutic outcomes. In line with this, Jiang et al 21 also verified that early intervention with 595-nm PDL combined with 755-nm long-pulse alexandrite laser can reduce the incidence of IH sequelae. The incidence of adverse reactions during the treatment was low, with only 28 cases (24.14%) showing hyperpigmentation, hypopigmentation, scarring, and blistering, in addition to the lack of systemic adverse effects.…”

Section: Discussionmentioning

confidence: 68%

The Application of Color Doppler Ultrasound in the Evaluation of the Efficacy of 595-nm Pulsed Dye Laser Combined with 755-nm Long-Pulse Alexandrite Laser in the Treatment of Hybrid Infantile Hemangiomas

Zhou

Gao

et al. 2022

CCID

Self Cite

View full text Add to dashboard Cite

Purpose We used color Doppler ultrasound to conduct an objective evaluation of the 595-nm Pulsed Dye Laser (PDL) combined with 755-nm long-pulse alexandrite sequential laser treatment for hybrid IH. Patients and Methods A total of 116 cases of hybrid IH were selected for this study. The interval between laser treatments was around 4 weeks, and 6 laser treatments or complete removal of the tumor was the end point. All children underwent color Doppler ultrasonography at the 0th, 1st, 6th months of treatment. Children were grouped by gender, age (<6 months, ≥6 months), thickness (<8 mm, ≥8 mm), and location (face and neck, trunk, and extremities). Calculate the volume of IHs according to color Doppler ultrasound. The volume ratio before and after treatment was defined as the A-value. Treatment outcomes were defined as effective when the A-value <75%. Results In total, 74 cases (63.79%) had effective outcomes. Overall, the samples showed a statistically significant difference in the reduction of IH volume after 6 months of laser treatment (P < 0.001). The treatment of <6 months group had better efficacy than the ≥6 months group (P < 0.001), the treatment of thickness <8 mm group had better efficacy than the thickness ≥8 mm group (P < 0.001) and there was no significant difference in efficacy between the three different location groups (P > 0.05). Greater reduction in blood flow in the group with the effective outcome than in the group with the ineffective outcome (P < 0.001). Conclusion Color Doppler ultrasound can be applied to the diagnosis of hybrid IH and to the evaluation of treatment time and outcomes, and it can help clinicians recognize hybrid IH with greater accuracy. The earlier intervention for hybrid IH we perform, the better outcomes will be.

show abstract

Section: Discussionmentioning

confidence: 68%

The Application of Color Doppler Ultrasound in the Evaluation of the Efficacy of 595-nm Pulsed Dye Laser Combined with 755-nm Long-Pulse Alexandrite Laser in the Treatment of Hybrid Infantile Hemangiomas

Zhou

Gao

et al. 2022

CCID

Self Cite

View full text Add to dashboard Cite

show abstract

“…It also had the best results for thick IH with a thickness of 2-5 mm. 16,17 Currently, the more popular and efficient option for laser therapy of superficial IH is the pulsed dye laser (PDL). 25 However, thanks to the deeper penetration depth and greater fluence, the long-pulse alexandrite laser is more effective in treating hypertrophic IH, while paired with a skin cooling system to further minimize side effects.…”

Section: Long-pulse Alexandrite Laser In Vascular Lesionsmentioning

confidence: 99%

Applications of Long-Pulse Alexandrite Laser in Cosmetic Dermatology: A Review

Chen,

2023

CCID

View full text Add to dashboard Cite

The long-pulse alexandrite laser uses Cr 3+ :BeAl 2 O 4 crystals as the activation medium and has a 755nm wavelength and millisecond pulse duration. The long-pulse alexandrite laser has been utilized for hair removal, vascular lesions, pigmented lesions, and other conditions because melanin and hemoglobin in the skin, subcutaneous tissues, and skin appendages can specifically absorb this type of laser. To serve as a guide and source of inspiration for the clinical use of this type of laser, we review the present research status and advancement of the long-pulse alexandrite laser in the treatment of the aforementioned categories of disorders.

show abstract

“…The type of skin changes was classified as anetoderma, telangiectasia and erythema, hyperpigmentation, hypopigmentation, redundant skin, fibrofatty tissue, or scarring (Figure 1A-D). As described previously, 3,8 anetoderma was defined as wrinkled and rough-textured skin change. The kappa coefficient value in evaluating residual skin changes between 2 evaluators was as follows: 0.90 for anetoderma, 0.89 for telangiectasia and erythema, 0.84 for hyperpigmentation, 0.88 for hypopigmentation, 1.00 for redundant skin, and 1.00 for fibrofatty tissue.…”

Section: Assessment Of Residual Skin Changesmentioning

confidence: 99%

Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser

et al. 2022

View full text Add to dashboard Cite

BACKGROUNDInfantile hemangioma (IH) often causes cosmetic disfigurement. Early intervention with propranolol for large, high-risk lesions is recommended in the American Academy of Pediatrics' Clinical Practice Guideline. Conversely, strategies for the management of small, low-risk lesions have not been established; however, pulsed dye laser (PDL) is often used to treat these lesions.OBJECTIVETo investigate clinical outcomes of PDL in small IH lesions.PATIENTS AND METHODSFifty-three cases with 58 small IHs which did not meet the criteria for high-risk lesions in the guideline and were treated only with PDL were retrospectively reviewed. The characteristics of IHs and residual skin changes after treatment were evaluated.RESULTSForty-seven lesions (81.0%) were superficial hemangiomas, whereas 11 (19.0%) were combined-type. The median maximum diameter was 10.0 mm. Forty-five lesions (77.6%) exhibited various residual skin changes after PDL treatment, including anetoderma (53.5%), telangiectasia and erythema (43.1%), hyperpigmentation (34.5%), redundant skin (3.4%), and fibrofatty tissue (3.4%). Of these, the incidence of anetoderma and fibrofatty tissue were significantly higher in the combined group than in the superficial group (p = .036 and .033, respectively).CONCLUSIONEven small lesions, especially combined-type, often result in cosmetic problems after PDL treatment.

show abstract

Sequelae After Involution of Superficial Infantile Hemangioma: Early Intervention with 595-nm Pulsed Laser Combined with 755-nm Long-Pulsed Alexandrite Laser versus Wait-and-See

Cited by 9 publications

References 34 publications

The Application of Color Doppler Ultrasound in the Evaluation of the Efficacy of 595-nm Pulsed Dye Laser Combined with 755-nm Long-Pulse Alexandrite Laser in the Treatment of Hybrid Infantile Hemangiomas

The Application of Color Doppler Ultrasound in the Evaluation of the Efficacy of 595-nm Pulsed Dye Laser Combined with 755-nm Long-Pulse Alexandrite Laser in the Treatment of Hybrid Infantile Hemangiomas

Applications of Long-Pulse Alexandrite Laser in Cosmetic Dermatology: A Review

Clinical Outcomes of Small Infantile Hemangiomas Treated With Pulsed Dye Laser

Contact Info

Product

Resources

About