Sepse por Staphylococus aureus resistente à meticilina adquirida na comunidade no sul do Brasil

Abstract

O Staphylococcus aureus faz parte da microbiota natural, principalmente da pele, podendo tornar-se patogênico em condições como a quebra da barreira cutânea ou diminuição da imunidade. Os traumas que comprometem a integridade da barreira cutânea constituem-se na principal causa de mudança de comportamento deste microrganismo, para o agente etiológico mais comum de infecções cutâneas 1 2 6 .As infecções mais comuns envolvem a pele (celulite, impetigo) e feridas em sítios diversos. Algumas infecções por Staphylococcus aureus são agudas, piogênicas e podem disseminar para diferentes tecidos e provocar focos metastáticos. Episódios mais graves, como bacteremia, pneumonia, osteomielite, endocardite, ABSTRACTMethicillin-resistant Staphylococcus aureus was initially described as a typical microorganism acquired in nosocomial infections. However, over recent years, community-acquired methicillin-resistant Staphylococcus aureus has been a cause of skin and soft-tissue infections. Serious infections such as pneumonia and sepsis can also occur. This report describes a case of sepsis in a child that was complicated by pneumonia secondary to soft tissue lesions that were due to community-acquired methicillin-resistant Staphylococcus aureus in southern Brazil. The patient was attended at the Emergency Unit with a history of injury caused by lower-limb trauma that evolved to cellulitis, pneumonia and sepsis. Tradicionalmente, as infecções causadas por este patógeno estavam limitadas aos hospitais, porém, a partir da década passada, infecções foram descritas em todo o mundo, de forma

Antimicrobial resistance profile of Staphylococcus aureus isolates obtained from skin and soft tissue infections of outpatients from a university hospital in Recife -PE, Brazil

“…In 2009, for example, two cases of skin and soft tissue infection caused by CA-MRSA were reported in the city of Porto Alegre. 19,20 In the same year, Rozenbaum et al reported the case of 10-year-old non-immunocompromised girl, who had been admitted to a hospital in the city of Rio de Janeiro in 2007, presenting clinical manifestations of septic shock, and from whom MRSA was isolated. Seven days before admission, the patient had developed furunculosis involving the buttocks and cellulite in the left thigh; and she had no history of previous hospitalization or healthcare-associated procedures in the last year.…”

PESQUISA DE Staphylococcus aureus NAS MAÇANETAS DAS PORTAS DOS QUARTOS DE UM HOSPITAL DA REGIÃO NOROESTE DO ESTADO DO RIO GRANDE DO SUL

“…10 Fatores como internação em unidades de terapia intensiva (UTIs), hospitalização prolongada, procedimentos invasivos e exposição repetida a antibióticos propiciam o contato com o agente. 11,12,13 A presença de determinados microorganismos em fômites hospitalares pode indicar condições higiênicosanitárias insatisfatórias, representando, também, uma importante fonte de transmissão de enfermidades. 14 Frente a isso, o presente trabalho tem o propósito de analisar a presença de S. aureus nas maçanetas das portas dos quartos hospitalares, por ser um fômite que proporciona, de forma facilitada, a transmissão de tal agente infeccioso.…”

CA-MRSA: Epidemiology of a Pathogen of a Great Concern

“…Several countries reported their presence as an emerging pathogen, including the United States, Australia, New Zealand, Samoa, several EU countries (Ribeiro et al, 2005) and South America (Brazil, Uruguay and Colombia) (Alvarez et al, 2006). In Brazil there are several case reports confirming the presence of this pathogen in the community involving cases of furunculosis (Razera et al, 2009), metastatic infections with major complications (Strong et al, 2008) and pneumonia (d 'Azevedo et al 2009;Gelatti et al, 2009). …”

“…The treatment was maintained with www.intechopen.com teicoplamin for 36 days, and from day 7 with meropenem for 14 days, showing progressive improvement and was discharged after 72 days from the hospital. No family member was colonized by CA-MRSA (d 'Azevedo et al, 2009). …”

“…The clonal profile analyzed by PFGE found that the strain was similar to clone OSPC. The patient remained hospitalized for 50 days and was discharged after treatment with clindamycin and gentamicin (Gelatti et al, 2009). Reinert et al (2008), analyzed a culture collection grown between 1995 and 1999 and characterized them by PFGE (electrophoresis in pulsed-field gel).…”