Separation of stereoisomers of aminoglutethimide using three capillary electrophoretic techniques

Selector-selectand interactions in chiral capillary electrophoresis

“…Therefore, it is sometimes useful to examine the results obtained by one of these techniques by using the other one. For example, the previous studies showed that the enantioseparation of aminoglutethimide (AG) is possible when a-and g-CDs are used as chiral selectors [24] but not when b-CD is used [24,25]. In fact, the studies performed using 1 H-and 13 C-NMR spectroscopy indicated that all three native CDs recognized the enantiomers of AG stereoselectively (Chankvetadze et al, in preparation).…”

Enantioseparation of phenothiazines in CD‐modified CZE using single isomer sulfated CD as a chiral selector

“…The electrophoretic migration of chiral compounds can be modified through the complexation of the enantiomers of analytes with various CDs, thus resulting in differences in the electrophoretic mobility of the enantiomeric complexes. For charged chiral compounds, enantioseparation can be achieved with neutral or charged CDs [8][9][10][11][12][13][14][15][16] or with dual CD systems consisting of a charged CD and a neutral CD [15][16][17][18][19][20][21][22][23][24][25] or two charged CDs [26]. Among many charged CDs studied to date, sulfated CDs have demonstrated the widest application range [8][9][10][11].…”

Strategies for enantioseparations of catecholamines and structurally related compounds by capillary zone electrophoresis using sulfated β-cyclodextrins as chiral selectors

“…Enantioseparation of charged compounds has often been achieved with the use of neutral or charged CDs [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20], or with dual CD systems consisting of a charged CD and a neutral CD [21][22][23][24][25][26][27][28][29], or two oppositely charged CDs [30]. Among many charged CDs studied to date, sulfated CDs have demonstrated the widest application range [6][7][8].…”