Separation and determination of Vitamins E and A in multivitamin syrup using micellar liquid chromatography and simplex optimization

Flow-Injection Determination of Retinol and Tocopherol in Pharmaceuticals with Acidic Potassium Permanganate Chemiluminescence

“…These include colorimetry/spectrophotometry, 7,8 spectrofluorometry, 9 voltammetry, 10 HPLC coupled with ultraviolet, fluorescence, photodiode array and electrochemical, [11][12][13][14][15][16] and chemiluminescence 17 methods that are reflected in a number of reviews. 5,6 Chemiluminescence (CL) as a technique can be used for determining trace and ultra-trace concentrations of inorganic and organic species (like drugs or pesticides) in a variety of industrial, clinical and environmental matrices.…”

HPLC method for simultaneous determination of retinol, α-tocopherol and coenzyme Q10 in human plasma

“…The same technique was used for assaying Vitamins A and E in milk powder samples after supercritical fluid extraction [16]. The chromatographic behaviour of tocopherols [17] and Vitamin A [18] in micellar medium was the base of their separation and quantification with UV detector in serum [17] and syrup [18] samples. Normal phase liquid chromatography (NP-HPLC) with the use a silica column was applied for determination of carotene, tocopherols and tocotrienols in palm's oil [19].…”

Application of simplex optimization in the development of an automated online preconcentration system for manganese determination

“…10,11,12 Simplex design methodology has been applied to optimize some analytical methods, such as solid-phase microextraction coupled to CG-MS for polycyclic aromatic hydrocarbons determination in water samples, 13 determination of amphetamine, amphetamine analogues, cocaine, and heroin in illicit tablets using capillary zone electrophoresis, 14 amoxicillin and clavulanic acid determination using sequential injection analysis with a diode-array spectrophotometer, 15 separation and determination of vitamins A and E using micellar liquid chromatography, 16 kinetic determination of nabumetone, a non-steroidal anti-inflammatory drug, by means of micellarstabilized room temperature phosphorescence, 17 flow injection analysis system for tartaric acid determination in wines 18 and ion-pair reversed phase high performance liquid chromatographic analysis of 4-(2-pyridylazo) resorcinol chelates of Co(II), Ni(II) and Cr(III). 19 Our research group has developed automated preconcentration system for metals determination using, as examples, cloud-point extraction where metal ions are complexed in a mixture of the reagent 2-[2′-(6-methylbenzothiazolylazo)]-4-bromophenol (Me-BTABr) and Triton X-114.…”