Sentinel serosurveillance of backyard hens proved West Nile virus circulation in the western provinces of Turkey

Albayrak, Harun; Sahindokuyucu, Ismail; Müftüoğlu, Bahadır; Tamer, Cüneyt; Kadı, Hamza; Özan, Emre; Yılmaz, Özge; Kılıç, Hamza; Kuruçay, Hanne Nur; Çöven, Fethiye; Gümüşova, Semra; Yazıcı, Zafer; Elhag, Ahmed Eısa

doi:10.1002/vms3.589

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…The presence of the West Nile virus in various mosquito species, especially of the genus Culex , and bird species has been documented in field studies conducted in various regions of Turkey. 6 – 11 , 20 In this study, in line with the density and distribution of the Culex genus documented in previous studies, WNV seropositivity was tested in healthy individuals in the Alanya region.…”

Section: Discussionmentioning

confidence: 81%

West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey

Bektore,

Dogan,

Ozkul

et al. 2024

Ann Saudi Med

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BACKGROUND: West Nile virus (WNV)-related illness is a global health problem. Understanding the seropositivity rates and identifying the risk factors related to WNV in various animal species including humans is crucial for the implementation of effective prevention strategies. OBJECTIVES: Assess the rate of seropositivity and the risk factors associated with WNV seropositivity. DESIGN: Descriptive, cross-sectional SETTING: Microbiology and virology departments in a veterinary college PATIENTS AND METHODS: In a sample of healthy human participants in Alanya, located close to regions where WNV activity has been detected, anti-WNV IgG antibody detection was performed using enzyme-linked immunosorbent assays. The positive results were confirmed by virus neutralization tests (VNTs). The sample was compared with a second group of age- and gender-matched healthy subjects selected from a previous cross-sectional study. MAIN OUTCOME MEASURES: Determination of the seropositivity and risk factors that were associated with WNV in healthy humans. SAMPLE SIZE: 87 in current study; 356 in previous study. RESULTS: The first group of 87, which had a high risk of encountering vector mosquitoes, had a positivity rate of 8% (7/87), whereas positivity in the second group was 4.5% (16/356; P =.181). In the entire sample, the anti-WNV IgG antibody was positive in 23 out of 443 (5.2%) samples by the ELISA test. Among these 23 samples, ten were confirmed as positive using VNTs. Therefore, the WNV IgG seropositivity was 2.3% (10/442). Confirmed IgG seropositivity rates were higher among male (3.8%) than female participants (0.9%; P =.054) and among adults aged ≥45 years (4%) than those aged 18-44 years (0.8%; P =.048). CONCLUSION: This study highlights the presence of WNV infection in the research region. More comprehensive and multidisciplinary studies are required to increase our knowledge about this zoonotic infection including risk factors in line with the One Health approach. LIMITATIONS: Small sample size.

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Section: Discussionmentioning

confidence: 81%

West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey

Bektore,

Dogan,

Ozkul

et al. 2024

Ann Saudi Med

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Sentinel serosurveillance of backyard hens proved West Nile virus circulation in the western provinces of Turkey

Albayrak

Sahindokuyucu

Müftüoğlu

et al. 2021

Veterinary Medicine & Sci

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West Nile virus (WNV) is a mosquito-borne virus of a re-emergence importance with a wide range of vertebrate hosts. Granted, it causes asymptomatic infection, but fatal cases and neurologic disorders were also recorded, especially in humans, horses and some exposed birds. The virus is globally spread and birds are considered an amplifying and reservoir host of WNV, helping to spread the disease due to their close contact with main hosts. In this study, we aimed to detect the presence of antibodies against WNV in backyard hens that were reared in the western Anatolian part of Turkey. A total of 480 chicken sera were randomly collected from six provinces in the west of Turkey (Mugla, Izmir, Aydin, Afyonkarahisar, Kutahya and Manisa) with 80 samples from each province (40 in spring and 40 in fall seasons). They were tested by using a competitive ELISA method to identify the specific avian antibodies of IgG that produced against the WNV envelope proteins (pr-E). Twelve of 480 (2.5%) sera were found seropositive, three of these positive sera were detected from the Izmir province (3.75%) collected in the spring session and the other nine positive sera were detected from the Mugla province (11.25%) collected in the fall session. Both of these provinces are located seaside and have suitable climate conditions for vectors of infection. The results indicated that WNV infection is in circulation in these provinces, and that may put the other susceptible vertebrates under risk of infection.

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Sentinel serosurveillance of backyard hens proved West Nile virus circulation in the western provinces of Turkey

Cited by 2 publications

References 31 publications

West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey

West Nile virus seropositivity in Alanya, a coastal city in the Mediterranean region of Turkey

Sentinel serosurveillance of backyard hens proved West Nile virus circulation in the western provinces of Turkey

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