Sentinel node biopsy and standard of care for melanoma: A re-evaluation of the evidence

Kanzler, Matthew H.

doi:10.1016/j.jaad.2009.08.063

Cited by 12 publications

(4 citation statements)

References 18 publications

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“…1 99m-Tc-nanocoll scintigram; site of injection, popliteal fossa, and SLN detection at the inguinal region Fig. 2 The histology report was positive for malignant melanoma without malignant infiltration of the SLN, nor in H&E staining neither in HMB-45 marker SLN biopsy does not improve survival but it is a common practice in the staging procedure [6]. The identification of SLN through lymphoscintigraphy and lymphatic mapping and the subsequent positivity for melanoma, are indicative of the indispensable completion lymphadenectomy which might improve survival [5].…”

Section: Discussionmentioning

confidence: 99%

Calcaneal Melanoma; Our Rare Case and Review of the Literature

2010

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Section: Discussionmentioning

confidence: 99%

Calcaneal Melanoma; Our Rare Case and Review of the Literature

2010

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“…However, the performance of sentinel node biopsies in malignant melanomas is still very uncommon and we get such biopsies for reporting very rarely. This is in spite of the fact that studies have shown that sentinel node biopsy is very accurate as a staging procedure and a powerful predictor of prognosis (Balch et al, 2009;Kanzler, 2010). We use the American Joint Committee on Cancer (AJCC) staging system for malignant melanomas (Balch et al, 2001).…”

Section: Dermatopathologymentioning

confidence: 99%

How Our Practice of Histopathology, Especially Tumour Pathology has Changed in the Last Two Decades: Reflections from a Major Referral Center in Pakistan

Ahmad

Idrees²,

Fatima³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Continued advances in the field of histo pathology (and cyto pathology) over the past two decades have resulted in dramatic changes in the manner in which these disciplines are now practiced. This is especially true in the setting of a large university hospital where the role of pathologists as clinicians (diagnosticians), undergraduate and postgraduate educators, and researchers has evolved considerably. The world around us has changed significantly during this period bringing about a considerable change in our lifestyles and the way we live. This is the world of the internet and the world-wide web, the world of Google and Wikipedia, of Youtube and Facebook where anyone can obtain any information one desires at the push of a button. The practice of histo (and cyto) pathology has also evolved in line with these changes. For those practicing this discipline in a poor, developing country these changes have been breathtaking. This is an attempt to document these changes as experienced by histo (and cyto) pathologists practicing in the biggest center for Histopathology in Pakistan, a developing country in South Asia with a large (180 million) and ever growing population. The Section of Histopathology, Department of Pathology and Microbiology at the Aga Khan University Hospital (AKUH) in Karachi, Pakistan's largest city has since its inception in the mid-1980s transformed the way histopathology is practiced in Pakistan by incorporating modern methods and rescuing histopathology in Pakistan from the primitive and outdated groove in which it was stuck for decades. It set histopathology in Pakistan firmly on the path of modernity and change which are essential for better patient management and care through accurate and complete diagnosis and more recently prognostic and predictive information as well.

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“…1 Dr Kanzler does an excellent job of summarizing the rationale for and the limitations of this procedure. We agree that at best sentinel lymph node biopsy (SNB) is a melanoma staging procedure, not a therapeutic procedure, and that SNB loses prognostic power with thin and thick melanomas and in older patients.…”

Section: Sentinel Node Biopsy Not Standard Of Care For Melanomamentioning

confidence: 99%