2004
DOI: 10.1016/j.ijporl.2004.05.009
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Sensorineural hearing loss in Nigerian children with sickle cell disease

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Cited by 46 publications
(68 citation statements)
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“…Several studies have suggested that HbS has an effect of protection against Plasmodium falciparum, the etiologic agent of malaria [6], showing that heterozygous people carrying the sickle-cell trait (HbAS) are protected against severe malaria (prevalence of HbAS, in some populations, is above 90%) [6,8].…”
Section: Introductionmentioning
confidence: 99%
“…Several studies have suggested that HbS has an effect of protection against Plasmodium falciparum, the etiologic agent of malaria [6], showing that heterozygous people carrying the sickle-cell trait (HbAS) are protected against severe malaria (prevalence of HbAS, in some populations, is above 90%) [6,8].…”
Section: Introductionmentioning
confidence: 99%
“…Of these 89 patients with SCD identified, 17 patients (14 males, 3 females; age, 10 -48 years) presented with inner ear symptoms and were evaluated by imaging of the brain or head and neck region or both. Presenting symptoms included SNHL (6 patients), dizziness, 6 vertigo, 5 and tinnitus, 3 or combination of multiple symptoms.…”
Section: Resultsmentioning
confidence: 99%
“…[1][2][3] The most accepted pathogenesis of inner ear involvement is recurrent vaso-occlusion of the labyrinthine blood vessels, which can result in LH and LO. [3][4][5][6][7][8][9] LH is thought to result from altered capillary hemodynamics or reperfusion injury. 9 The association between LH and LO has not been fully demonstrated, but it is theorized that LH incites a reparative response that cascades from fibrosis to sclerosis and ultimately ossification of the inner ear structures.…”
Section: Original Researchmentioning
confidence: 99%
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