Sensitization to fragrances in Spain: A 5‐year multicentre study (2011‐2015)

Abstract

Background: Fragrance chemicals constitute the second most frequent cause of contact allergy in Spain. There are no data available concerning the individual fragrances that are most frequently involved.Objectives: To describe the diagnostic contribution provided by specific fragrance series to the results obtained with baseline series fragrance markers by correlating the results of both series. Materials and methods:We performed a 5-year retrospective study of fragrance markerpositive patients tested with specific fragrance series in 23 Spanish centres. We collected the demographic and clinical characteristics, and compared the results of patch tests obtained from different suppliers.Abbreviations: CI, confidence interval; FM, fragrance mix; HICC, hydroxyisohexyl 3-cyclohexene carboxaldehyde; MP, Myroxylon pereirae.*P < 0.05 in χ 2 tests for group differences.

European photopatch test baseline series: A 3‐year experience

“…It has to be emphasized that the patch test baseline series should also be tested when suspected "sun-exposed dermatitis" is investigated, because (photoaggravated) allergic contact dermatitis, for example, to isothiazolinones can mimic photoallergic contact dermatitis, as shown in our patients and as previously described in the literature. [21][22][23][24][25][26][27][28] In conclusion, our results are in accordance with those published for the consensus photopatch test series. They confirm the usefulness of the European photopatch test baseline series.…”

Changing trends of contact allergens in Thailand: A 12‐year retrospective study

“…Regarding cosmetic allergens, the reduced prevalences of fragrance mix I allergy and fragrance mix II allergy have most probably resulted from the replacement of those fragrances with the numerous alternatives that are now available for use in cosmetics that do not have to be labelled. 20,21 Thus, fragrance mixes I and II might no longer be sufficient for screening for fragrance contact allergy in patients, and new substances may need to be added to baseline series. Conversely, the prevalence of Myroxylon pereirae resin allergy did not significantly change in the current study period.…”

Myroxylon pereirae resin (balsam of Peru) – A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets

“…5,46,47 In Spain, positivity rates were 2.4%, 6.4%, and 5.8%. 31,48,49 In Sweden, 4.8% to 6.5% of routine patients reacted to MP. 27,30,50 Other European countries have also presented their patch test results with MP: The Netherlands, 2.8% (the low frequency probably resulting from the use of TRUE Test); Finland, 6.2%; Belgium, 6.1%; Switzerland, 7.8%; and the Czech Republic, 7.3%.…”

“…29,30 In almost all studies, MP allergy occurred significantly more often in the older (>40 years) age groups. 26,27,[29][30][31] In a large Information Network of Departments of Dermatology (IVDK) study, risk quantified by the prevalence ratio rose with increasing age vs reference (age T A B L E 1 Ingredients identified in Myroxylon pereirae resin (MP), extracts, and essential oils (adapted from Ref. 5 1-36 years) from 1.87 (age 37-50 years) and 2.79 (age 51-64 years) to 3.32 (age 65-99 years).…”