Sensitivity to meat protein intake and hyperoxaluria in idiopathic calcium stone formers

Nguyen, Q; Kälin, Agnes; Drouve, Uschi; Casez, Jean-Paul; Jaeger, Philippe

doi:10.1046/j.1523-1755.2001.00744.x

Cited by 78 publications

(33 citation statements)

References 33 publications

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“…A high animal protein diet increases urinary calcium, uric acid, oxalate, and phosphorus and decreases urinary citrate and pH, as an effect of a higher intake of purine and phosphorus and urinary acidification [7-9]. Similar lithogenic changes have been reported with high carbohydrate and fat intake [10-12].…”

Section: Introductionmentioning

confidence: 88%

Dietary habits in women with recurrent idiopathic calcium nephrolithiasis

et al. 2012

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BackgroundNutrition has been widely recognized to influence the risk of kidney stone formation. Therefore the aim of our study was to assess: a) whether usual diet of women with idiopathic calcium nephrolithiasis (ICN) living in Parma (Northern-Italy) is different compared to healthy controls, b) how their diet differs from Italian National guidelines and c) whether it is related to nephrolithiasis clinical course.Methods143 women with recurrent ICN (mean age 43 ± 13 ys) and 170 healthy women (mean age 42 ± 11 ys) were enrolled. All women completed a food frequency questionnaire for the last 60-days and a 3-day dietary diary analysed with a dedicated software.ResultsStone formers showed a higher consumption of sausages, ham, meat and sweets than healthy controls (43.1% vs 11.1%, 29.4% vs 13.9%, 21.6% vs 4.2%, 66.7% vs 18.1%, p < 0.001). The 3-day diary analysis showed an intake of calories, carbohydrates, lipids and non-discretionary sodium about 10% higher than healthy controls (p < 0.001). Finally, after dividing the population into 3 age groups (≤30, 31-40, > 40 years), the differences described above were amplified in the class ≤30 years, where nephrolithiasis presented a more serious course (shorter recurrence interval, greater stone-rate). In this age group the intake of fruit and vegetables was notably lower than guideline recommendations.ConclusionsWe conclude that the usual diet of women with recurrent ICN is different from controls and characterized by low intake of fruits and vegetables and higher consumption of simple sugars and foods with high protein and salt content. This dietary imbalance could play a role in the ICN pathogenesis, especially in younger women.This work was financed by grants from Italian Ministry of University and Research as part of a larger project about the prevention of kidney stones (PRIN 2005063822) and by Fondazione per la Ricerca Scientifica Termale (FoRST). No potential conflict of interest relevant to this paper was reported.

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Section: Introductionmentioning

confidence: 88%

Dietary habits in women with recurrent idiopathic calcium nephrolithiasis

et al. 2012

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“…For comparable animal protein loads, these urinary effects are more marked in stone formers, suggesting that these subjects may have a genetic hypersensitivity to such foods. 27 The increase in uricosuria and phosphaturia is directly related to the high purine and phosphorus content of animal proteins. The increase in calciuria and decrease in citraturia and urine pH are mainly attributed to the acidifying effect of their high content in sulfurated amino acids (methionine and cysteine).…”

Section: Proteinsmentioning

confidence: 99%

Dietary Therapy in Idiopathic Nephrolithiasis

Borghi¹,

Meschi²,

Maggiore³

et al. 2006

Nut. Rev.

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Like other diseases striking predominantly the affluent societies, idiopathic nephrolithiasis is increasing in rich countries and appears to be closely related to dietary habits. In this review we summarize the latest evidence about the efficacy of dietary treatment for idiopathic calcium and uric acid stones, dealing especially with its effect on the urinary stone risk factors, stone recurrences, and clinical limitations. After a short introduction on epidemiology and pathogenesis, we review the role of the most important foods and nutrients in stone formation and protection: water and other fluids, proteins, carbohydrates, fats, salt, milk and dairy products, fruits and vegetables, and vitamins. The final part of the paper will provide practical guidelines for pursuing an anti-lithogenic diet in idiopathic calcium and uric acid stones.

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“…In a study it was shown overconsumption of animal protein create observable increased rate of urinary calcium (23%) and oxalate (24%) [80]. High fructose consumption from soft drinks is associated with an increased risk of hypercalciuria, hyperoxaluria and hyperuricosuria [39,81]. In an experiment higher urinary calcium excretion occurred in rats fed high-fructose diets compared to rats fed high-starch diets [82,83].…”

Section: Calcium Stonementioning

confidence: 99%

Demographic Diversity of Food Intake and Prevalence of Kidney Stone Diseases in Indian Continent

Guha¹,

Banerjee²,

Mitra³

et al. 2018

Preprint

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Food intake plays a pivotal role of human growth, which necessarily contributes 45% of global economy and wellbeing in general. Consumption of balanced food is elementary for overall good health while a shift of equilibrium can lead to malnutrition, prenatal death, obesity, osteoporosis and bone fractures, coronary heart diseases (CHD), idiopathic hypercalciuria, diabetes and many more. Though CHD, osteoporosis, malnutrition, obesity are being classified thoroughly in the literature, there are fragmented findings in the regime of kidney stone diseases (KSD) and the correlation with food intake therein. KSD associated with hematuria and renal failure poses an increasing threat to the healthcare and global economy while its emergence of Indian populations is being affected with multi-factorial urological disorder resulting from several factors. In this realm, epidemiological, biochemical, macroeconomic situations been portrayed when food intake is also a paramount importance which rarely been forecasted. Hence, in this article we will be reviewing the corollary connotation with diverse food consumption and the efficacy it plays in KSD extrapolating in Indian context.

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Sensitivity to meat protein intake and hyperoxaluria in idiopathic calcium stone formers

Abstract: Approximately one third of ICSFs with or without so-called MMH are sensitive to meat protein in terms of oxalate excretion, as opposed to healthy subjects. Mechanisms underlying this sensitivity to meat protein remain to be elucidated and do not seem to involve vitamin B(6) deficiency.

Cited by 78 publications

References 33 publications

Dietary habits in women with recurrent idiopathic calcium nephrolithiasis

Dietary habits in women with recurrent idiopathic calcium nephrolithiasis

Dietary Therapy in Idiopathic Nephrolithiasis

Demographic Diversity of Food Intake and Prevalence of Kidney Stone Diseases in Indian Continent

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