Sensitivity of Tru‐cut and fine‐needle aspiration biopsies of liver and kidney for diagnosis of feline infectious peritonitis

Abstract

Biopsy of liver and kidney can correctly identify FIP lesions. However, false-negative results or inadequate samples occur with moderate frequency, especially for immunochemical analysis. Diagnostic sensitivity may be increased when both TCB and FNAB specimens from the same organ are examined.

Performances of different diagnostic tests for feline infectious peritonitis in challenging clinical cases

“…Histopathology is considered the only method for a conclusive diagnosis (Sparkes and others 1991, 1994, Pedersen 2009). However, the low yield of histopathological lesions in tru‐cut sections limits the potential application of this approach for ante‐mortem diagnosis of FIP (Giordano and others 2005).…”

Urinary Tract

“…Samples obtained by FNA can also be submitted for fungal culture or other diagnostic techniques (e.g., polymerase chain reaction). Finally, feline infectious peritonitis is uncommonly diagnosed using cytology (Giordano et al, 2005). Aspirates have a mixed pyogranulomatous inflammation with a basophilic, proteinaceous background.…”

Fine needle aspiration of abdominal organs: a review of current recommendations for achieving a diagnostic sample

“…Interestingly, in one study, liver FNA specimens had high diagnostic sensitivity (82%) for feline infectious peritonitis (FIP) in cats, which was more impressive than the use of core biopsy (64% Se) (Giordano et al 2005 ). Nevertheless, the cytological findings of pyogranulomatous inflammation are not specific for FIP and can be seen in many other disease processes.…”

“…When assessing 22 cats with FIP for the diagnostic sensitivity of detecting FIP in renal lesions, Giordano et al ( 2005 ) found that sensitivity using core biopsy (39%) was similar to FNA specimens (42%).…”