Sensitive and selective determination of fluvoxamine maleate using a sensitive chemiluminescence system based on the alkaline permanganate–Rhodamine B–gold nanoparticles reaction

Abstract

A high-yield chemiluminescence (CL) system based on the alkaline permanganate-Rhodamine B reaction was developed for the sensitive determination of fluvoxamine maleate (Flu). Rhodamine B is oxidized by alkaline KMnO4 and a weak CL emission is produced. It was demonstrated that gold nanoparticles greatly enhance this CL emission due to their interaction with Rhodamine B molecules. It is also observed that sodium dodecyl sulfate, an anionic surfactant, can strongly increase this enhancement. In addition, it was demonstrated that a notable decrease in the CL intensity is observed in the presence of Flu. This may be related to Flu oxidation with KMnO4 . There is a linear relationship between the decrease in CL intensity and the Flu concentration over a range of 2-300 µg/L. A new simple, rapid and sensitive CL method was developed for the determination of Flu with a detection limit (3s) of 1.35 µg/L. The proposed method was used for the determination of Flu in pharmaceutical and urine samples.

Inhibition of rhodamine B–ferricyanide chemiluminescence by Au nanoparticles toward the sensitive determination of mercury (II) ions

“…These NPs based CL systems have been applied to sensitive monitoring of important analytes in various media [29]. For example, cyanide and fluvoxamine determination based on Au NPs-alkaline permanganate-RB CL reaction have been reported [30,31]. To the best of our knowledge, the reported CL-NPs systems are almost based on the enhancement effect of NPs in CL intensity, and there is no report for the analytical application with the inhibiting effect of NPs on CL systems.…”

Inhibition of Rhodamine B-Ferricyanide Chemiluminescence by Gold Nanoparticles and Sensitive Determination of Hazardous Cyanide

“…This decrease was connected to electrostatic and π interaction of RohB molecules with negative citrate moieties of AuNPs, and was previously exploited to analytical aims in fluorescence 34,35 and CL fields. [8][9][10] On the other hand, absorption of AuNPs declined due to the addition of Fe(CN) 6 3- (Fig. S2b, Supporting Information), which indicates the oxidation reaction between them.…”

“…The acceptor role of RohB molecules has been regularly reported in CL reactions. [8][9][10] Quenching effect of AuNPs on the produced CL emission can be explained in two ways. (1) Resonance energy transfer between RohB as donor and AuNPs as acceptor 34,35 and (2) consumption of Fe(CN)6 3-by AuNPs.…”

“…[3][4][5] Ag and AuNPs can act mainly as catalysts in CL reactions. There are many reports in the literature describing the analytical use of gold [3][4][5][6][7][8][9][10] and silver [3][4][5]11,12 NPs-catalyzed CL reactions. Practically all of these reported CL-NPs systems are based on the enhancement effect of NPs on CL intensity.…”

“…For instance, our group reported several NPs-enhanced CL systems applied to sensitive monitoring of important analytes in various media. [8][9][10] According to our best knowledge, the inhibiting effect of NPs on CL systems has not been applied for analytical aims. [3][4][5] Cyanide (CN -) is a most rapidly acting and powerful poison that can bind to the active site of cytochrome c oxidase, interfering with electron transport and resulting in suppressed cellular respiration.…”