Seminal vesicles ultrasound features in a cohort of infertility patients

Lotti, Francesco; Corona, Giovanni; Colpi, Giovanni M.; Filimberti, E.; Innocenti, S. Degli; Mancini, Mario; Baldi, Elisabetta; Noci, Ivo; Forti, Gianni; Maggi, Mario

doi:10.1093/humrep/des032

Cited by 54 publications

(116 citation statements)

References 20 publications

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“…Transrectal ultrasound is the gold standard for SV and internal genitalia assessment in cases of obstructive azoospermia. 5 Pelvic MRI is required when ultrasound is insufficient or when it shows a major ductal dilatation. 6 SV and vas deferens normally appear hyperintense on T2 due to the seminal fluid they contain in their light.…”

Section: Discussionmentioning

confidence: 99%

Seminal vesicle agenesis: An uncommon cause of azoospermia

Bouzouita

Kerkeni

Abouda³

et al. 2014

CUAJ

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Seminal vesicle malformations are a rare cause of obstructive azoospermia, often associated with other internal genitalia and upper urinary tract birth defects. We report 5 new cases of seminal vesicle agenesis in men presenting with hypospermia and azoospermia. Imaging showed seminal vesicle unilateral agenesis in all patients. The remaining seminal vesicle was hypoplastic in 3 cases, dilated in 1 case and with abnormally thick content in another case. Vas deferens agenesis was observed unilaterally in 2 patients and bilaterally in 2 other patients. No renal malformations were detected. Genetic study showed in all cases a 46 XY karyotype without any microdeletions. A single heterozygous cystic fibrosis transmembrane regulator gene mutation was diagnosed in 1 man, but not found in his partner. Intracytoplasmic sperm injection using sperm from a testicular biopsy was performed in 3 couples, without success.

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Section: Discussionmentioning

confidence: 99%

Seminal vesicle agenesis: An uncommon cause of azoospermia

Bouzouita

Kerkeni

Abouda³

et al. 2014

CUAJ

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“…© 2012 American Society of Andrology and European Academy of Andrology A last aspect concerns the use of an ultrasound parameter, the so-called 'ejection fraction of the seminal vesicles' (Lotti et al, 2012) that appears to increase significantly after prolonged treatment with tadalafil at low daily doses in patients with DM and DN. To our knowledge, there are no other data in the literature regarding the application of this parameter in unconventional categories of infertile patients.…”

Section: Discussionmentioning

confidence: 99%

“…For the first time, we also evaluated another ultrasound parameter, the so-called 'SV ejection fraction', calculated as [(SV volume before ejaculation À SV volume after ejaculation)/SV volume before ejaculation] 9 100 (Lotti et al, 2012). This article describes also how to calculate the initial SV volume (Lotti et al, 2012).…”

Section: Ultrasound Evaluationmentioning

confidence: 99%

Seminal vesicles and diabetic neuropathy: ultrasound evaluation after prolonged treatment with a selective phosphodiesterase‐5 inhibitor

et al. 2012

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SUMMARYWe have previously reported that infertile patients with diabetes mellitus (DM) have a particular ultrasound features of the seminal vesicles (SV) characterized by higher fundus-to-body ratio and lower pre-and post-ejaculatory difference in body antero-posterior diameter (APD). Based on these premises the aim of the present study was to investigate possible ultrasound SV changes in infertile patients with DM and diabetic neuropathy (DN), after prolonged administration of tadalafil (TAD) (a specific phosphodiesterase-5 inhibitor). To accomplish this, 20 infertile patients with symptomatic DN and erectile dysfunction were selected and arbitrarily divided into two groups which were assigned to: daily administration of 5 mg TAD for 3 months (Group A) (n = 10) and administration of placebo (Group B) (n = 10). All patients underwent to scrotal and prostate-vesicular transrectal ultrasound evaluation and semen analysis (Laboratory Manual for the Examination and Processing of Human Semen, WHO, 2010) before and after treatment. The following SV US parameters were recorded: (i) body APD; (ii) fundus APD; (iii) parietal thickness of the right and left SVs; and (iv) number of polycyclic areas within both SVs. We then calculated the following parameters: (i) fundus/body (F/B) ratio; (ii) difference of the parietal thickness between the right and the left SV and (iii) pre-and post-ejaculatory APD difference. In addition, we also evaluated the SV ejection fraction. Group A patients showed a significant reduction in F/B ratio and higher pre-and post-ejaculatory body SV APD difference compared with baseline or Group B after 3 months. These patients showed also a significant increase in SV ejection fraction and a significant improvement of the total sperm count, progressive motility, seminal levels of fructose, leucocytes and ejaculate volume. In conclusion, these results suggest that infertile DM patients with DN and erectile dysfunction had an improvement of ultrasound features suggestive of diabetic neuropathy after daily treatment with low doses of TAD.

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“…1). 15 All measurements were performed twice, and the mean lengths were taken into consideration for calculation. Final seminal vesicle volume was determined by the arithmetic average of both seminal vesicle volumes.…”

Section: Methodsmentioning

confidence: 99%