Semiautomatic method for the ultra-trace arsenic speciation in environmental and biological samples via magnetic solid phase extraction prior to HPLC-ICP-MS determination

Atomic Spectrometry Update: review of advances in elemental speciation

“…Good recoveries of 89 to 96% and 90 to 102% were achieved for As III and As V , with RSDs of 3.2 to 8.0% and 2.5 to 7.6%, respectively. In the second study, a magnetic functionalised material based on graphene oxide and magnetic NPs (previously reported by the authors) was used to develop a magnetic SPE method to pre-concentrate inorganic and organic As species via a FI system prior to their indirect determination by HPLC-ICP-MS. 36 During a 180 s sample loading period, at a flow rate of 4 mL min −1 , As species were retained on the functionalised magnetic nanomaterial and then eluted into a chromatographic vial for subsequent introduction to the HPLC-ICP-MS. The method was evaluated for use with environmental waters and biological samples and under optimised conditions gave LOD values of 3.8 ng L −1 for AB, 0.5 ng L −1 for cacodylate, 1.1 ng L −1 for As III and 0.2 ng L −1 for As V with RSDs of <5%.…”

Magnetic graphene oxide as a valuable material for the speciation of trace elements

“…Montoro-Leal et al developed a MSPE method to enrich both, inorganic and organic arsenic species (AsBet, cacodylate, As III and As V ) in biological samples and environmental waters [88]. A novel MGO functionalized with [1,5-bis (2-pyridyl) 3-sulfophenylmethylene] thiocarbonohydrazide (MGO-PSTH) was used as solid phase adsorbent.…”

“…Under the optimized conditions, the LODs and EF for the arsenic species were 3.8 ng L À1 AsBet, 0.5 ng L À1 cacodylate, 1.1 ng L À1 As III and 0.2 ng L À1 As V with RSDs <5%. Urine, well-water, and seawater samples were analysed, showing promise for routine monitoring of arsenic species in biological fluids and environmental samples [88].…”

Rapid automated total arsenic and arsenic speciation by inductively coupled plasma mass spectrometry

“…The most common methodology for measuring total arsenic is performed using an inductively coupled plasma-mass spectrometer (ICP-MS), whereas determining the arsenic species is typically done by chromatographic separation prior to introduction to the ICP-MS. A large amount of work has been dedicated to this topic in recent decades, however the resulting methods are generally lengthy, offer only a sub-set of the arsenic species, and/or have high operational costs. 2,11,[14][15][16][17][18][19][20][21][22][23][24][25][26] Wegwerth et al presented the fastest method (2 minutes) for arsenic speciation to date but it did not include TMAO. 25 Ciardullo et al presented a method for seven arsenic species (AsB, AsC, DMA, MMA, TMAO, As(III), and As(V)), however 25 minutes were needed to complete the separation.…”