“…Thus, uncorrected (by experts) machine-generated annotations are likely to lead to incorrect predictions being reinforced during network optimization, which in turn leads to worse task performance at test time. To address this problem, a semi-supervised active learning (SSAL) strategy is sometimes used, which generally uses a pipeline of (i) query function for selecting “informative” samples from the annotation-free data pools, (ii) forwarding those to oracle annotators for generating ground truth annotation, and subsequently (iii) adding those new annotated data to the training data pool ( Zhao et al, 2021 , Gao et al, 2020b , Calma et al, 2018 , Lv et al, 2022 , Bull et al, 2018 ). However, such oracle annotation systems share limitations similar to those of expert supervision in medical imaging applications, namely, the time and labor requirements placed upon expert radiologists who are rarely available or interested in such manual dense annotation tasks, as well as the poor intra- and inter-annotator reproducibility.…”